| 不同透析膜对血透患者外周血细胞因子的影响 |
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| 引用本文： | 蒋红利,冯学亮,陈葳,马岚,杜娟.不同透析膜对血透患者外周血细胞因子的影响[J].西安交通大学学报(医学版),1998(4). |
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| 作者姓名： | 蒋红利 冯学亮 陈葳 马岚 杜娟 |
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| 作者单位： | 第一附属医院透析中心!西安，710061，第一附属医院透析中心!西安，710061，第一附属医院透析中心!西安，710061，第一附属医院透析中心!西安，710061 |
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| 摘 要： | 将24例长期血透（HD）患者随机分为3组，每组8例，分别采用钢仿膜、血体膜、聚砜膜透析器，以白细胞介素1β（IL－1β）、肿瘤坏死因子α（TNFα）作为膜生物相容性指标。用酶联免疫法测定3组患者血迹前、透析器首次使用及第4次使用后IL－1β、TNFα的水平。发现IL－1β、TNFα的水平依次为聚识膜＜血信膜＜铜仿膜，复用透析恐后IL-1β、TNFα水平与各组进前比无显著性差异（P＞0．05）。认为合成膜的生物相容性优于纤维素膜，复用透析器可改善膜的生物相容性。
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| 关 键 词： | 血液透析 生物相容性 细胞因子 透析器 |
EFFECT OF DIFFERENT MEMBRANES ON INTERLEUKIN-1β ANDTUMOR NECROSIS FACTOR α IN CHRONIC HEMODIALYSIS |
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| Jiang Hongli, Feng Xueliang, Chen Wei et al.EFFECT OF DIFFERENT MEMBRANES ON INTERLEUKIN-1β ANDTUMOR NECROSIS FACTOR α IN CHRONIC HEMODIALYSIS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1998(4). |
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| Authors: | Jiang Hongli Feng Xueliang Chen Wei |
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| Abstract: | in order to offer theoretie evidencefor clinic to select dialyzers reasonably, 24 chronichemodialysis patients were dialyzed with cuprophone (CU) hemophone (Hemo) and polysulphone(PS) dialyzer respectively. The interleukin-1β (IL1β) and tumor necrosis factor Q (TNFα) as markersof membrane biocompatibility were observed by enzyme immunoassay after using different dialysismembranes. IL-1β and TNFα were measured preand post hemodialysis when different dialyzers werefirst and fourthly used. The results demonstratedthat the levies of IL-1β and TNFα were PS
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| Keywords: | hemodialysis biocompatibility cytokine dialyzer |
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