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大鼠角膜移植排斥反应中体液免疫作用的研究
引用本文:张林,张德秀,SusanM.Nicholls. 大鼠角膜移植排斥反应中体液免疫作用的研究[J]. 西安交通大学学报(医学版), 1998, 0(2)
作者姓名:张林  张德秀  SusanM.Nicholls
作者单位:西安第一临床医学院眼科学教研室!西安,710061,西安第一临床医学院眼科学教研室!西安,710061,西安第一临床医学院眼科学教研室!西安,710061
摘    要:测定30例PVG-PVG和40例LEW-PWG角膜移植术前、术后血清、房水和泪液Ig和C3含量。结果表明,泪液和房水IgG含量异常升高与角膜移植排斥反应显著相关。初步建立了大鼠角膜移植术后无排斥反应发生时泪液IgG含量变化的定量关系,提出预测角膜移植术后排斥反应发生的一种辅助方法。

关 键 词:大鼠  角膜移植  排斥反应  泪液  抗体

A STUDY ON THE EFFECT OF HUMOAL IMMUNE IN RAT'S CORNEAL GRAFT REJECTION
Zhang Lin, Zhang Dexiu,Susan M. Nicholls. A STUDY ON THE EFFECT OF HUMOAL IMMUNE IN RAT'S CORNEAL GRAFT REJECTION[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1998, 0(2)
Authors:Zhang Lin   Zhang Dexiu  Susan M. Nicholls
Abstract:In the present study, two-group experiments were made to determine the concentration of Ig and C3 in serum,tear and aqueous humor from preoperated and postoperated eyes of PVG-PVG syngraft and PVG-LEW allograft. A abnormally significant increase of IgG level in tear and aqueous humor before and during comeal gratf rejection was observed. Statistically qualified variation of IgG concentration in tear from postoperated eyes of the syngraft rat was established and a new method to predict comeal rejection in postgraft eyes is proposed.
Keywords:rat  corneal graft  rejection  tear  IgG
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