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OKT10在淋巴瘤及多发性骨髓瘤淋巴细胞的表达
引用本文:郑成云,陈开浚,邵文斌.OKT10在淋巴瘤及多发性骨髓瘤淋巴细胞的表达[J].西安交通大学学报(医学版),1992(2).
作者姓名:郑成云  陈开浚  邵文斌
作者单位:西安医科大学第一附属医院内科学教研室,西安医科大学第一附属医院内科学教研室,西安医科大学第一附属医院内科学教研室 西安 710061,西安 710061,西安 710061
摘    要:本文利用OKT10检测了18例多发性骨髓瘤及35例恶性淋巴瘤患者外周血淋巴细胞,发现多发性骨髓瘤和非何杰金淋巴瘤患者OKT10阳性细胞均显著高于对照组,其改变与血清β_2微球蛋白水平无关。

关 键 词:外周血淋巴细胞  单克隆抗体  恶性淋巴瘤  多发性骨髓瘤

THE EXPRESSION OF OKT10 IN PHERIPHERAL BLOOD OF MALIGNANT LYMPHOMA AND MULTIPLE MYELOMA
Zheng Chengyun,Chen Kaijun,Shao Wenbin.THE EXPRESSION OF OKT10 IN PHERIPHERAL BLOOD OF MALIGNANT LYMPHOMA AND MULTIPLE MYELOMA[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1992(2).
Authors:Zheng Chengyun  Chen Kaijun  Shao Wenbin
Abstract:35 patients with malignant lymphoma and 18 patients with multiple mycloma were investigated for expression of OKT10in pherpheral blood. A significant incresing of OKT 10 positive cells was found in most of patients (26/30, 16/18 cases respectively) with Non-Hodgekin's Lymphoma(NIIL) and Multiple myeloma(MM). The inereasing of OKT10 positive cells is related to the degrce of malignaency of patients with NIIL from low-grade to high-wade. No relationship between serum beta-2-microglobulin and OKT10 positive cells in patients with NIIL and MM was also found.
Keywords:phedpheral blood lymphocyte  monoclonal antibody  malignant lymphoma  multiple mycloma
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