| 褪黑素与免疫调节细胞的关系 |
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| 引用本文： | 周爱民,范桂香,王军阳,任会勋,孟兆俊,袁育康.褪黑素与免疫调节细胞的关系[J].西安交通大学学报(医学版),2002,23(1):8-9. |
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| 作者姓名： | 周爱民 范桂香 王军阳 任会勋 孟兆俊 袁育康 |
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| 作者单位： | 西安交通大学医学院免疫学教研室,西安,710061 |
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| 摘 要： | 目的 探讨褪黑素与免疫调节细胞之间的关系。方法 采用流式细胞计数测定外周血T淋巴细胞亚群CD4+和CD8+T细胞的百分含量、比值。结果 褪黑素可提高外周血中CD4+和CD8+T细胞的百分含量 ,调整CD4+/CD8+比值。结论 褪黑素可通过调整免疫调节细胞TH/TS 的比例发挥免疫调节作用。
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| 关 键 词： | 褪黑素 CD4+T细胞 CD8+T细胞 免疫调节细胞(TH、TS) |
| 文章编号： | 0258-0659(2002)01-0008-02 |
| 修稿时间： | 2000年11月2日 |
Relationship between Melatonin and immunoregulatory cells |
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| Abstract: | Objective To investigate the relationship between melatonin and immunoregulatory cells. Methods We tested the percentage of CD4 + and CD8 +T lymphocytes and CD4 +/CD8 + by flow cytometer. Results Melatonin could increase the percentage of CD4 + and CD8 + T cells in the normal and the aged mouse, but did not change CD4 +/CD8 +. The difference was significant.In the group injected with cyclophosphamide, melatonin also could promote the percentage of CD4 + and CD8 + T cells, consequently changing CD4 +/CD8 +.Conclusion One of the regulatory mechanisms of melatonin is that melatonin can be functional in organism by mediating T H/T S. |
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| Keywords: | melatonin CD4 + T lymphocytes CD8 + T lymphocytes immunoregulatory cells (T H T S) |
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