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急性心肌梗塞患者血浆纤维蛋白原浓度及聚集功能的变化
引用本文:王燕妮,祝家庆,符明桂,马西.急性心肌梗塞患者血浆纤维蛋白原浓度及聚集功能的变化[J].西安交通大学学报(医学版),1996(3).
作者姓名:王燕妮  祝家庆  符明桂  马西
作者单位:西安第一临床医学院内科学教研室,西安医科大学实验血液研究室
摘    要:对10例急性心肌梗塞(AMI)患者及60例健康对照血浆纤维蛋白原(Fg)浓度及聚集功能测定表明:AMI患者血浆Fg浓度明显升高,Fg聚集功能明显增强,与对照组比较有明显差异(P<0.001);但Fg浓度升高并在病程中有动态变化,Fg聚集功能则无动态变化;AMI并发症组比无并发症组患者,上述2项指标均有明显升高(P<0.001)。提示Fg浓度升高及聚集功能增强与AMI的发病有一定关系,对其预后有一定参考价值。

关 键 词:急性心肌梗塞  纤维蛋白原浓度  纤维蛋白原聚集功能

CHANGES OF THE PLASMA FIBRINOGEN CONCENTRATION AND THE AGGREGATION FUNCTION OF THE FIBRINOGEN IN AMI
Wang Yanni,Zhu Jiaqing,Fu Minggui,et al.CHANGES OF THE PLASMA FIBRINOGEN CONCENTRATION AND THE AGGREGATION FUNCTION OF THE FIBRINOGEN IN AMI[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1996(3).
Authors:Wang Yanni  Zhu Jiaqing  Fu Minggui  
Abstract:The plasma fibrinogen concentration and its aggregation function were determined in ten patients with AMI and sixty healthy persons. The results showed that the plasma fibrinogen concentration and its aggregation function were significantly increased in AMI cases compared with those in the controls; the increase of the fibrinogen concentration showed a dynamic contribution during the course of AMI, but the enhancement of the aggregation function had no dynamic changes. the plasma fibrinogen concentration and its aggregation function were also significantly increased in AMI cases with complications compared with those without complications.This study indicated that the increase of the plasma fibrinogen concentration and its aggregation function were associated with AMI, and might be predictive indexes for the prognosis in AMI patients.
Keywords:AMI  fibrinogen concentration  aggregation function of fibrinogen
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