A PULSATION-TYPE PORTAL PUMP IN THE TREATMENT OF THE PORTAL HYPERTENTION

Ｌｉｖｅｒｃｉｒｒｈｏｓｉｓ ,ａｗｏｒｌｄｗｉｄｅｈｅａｌｔｈ ｐｒｏｂｌｅｍ ,ｄｅｃｒｅａｓｅｓｔｈｅｂｌｏｏｄｆｌｏｗｔｈｒｏｕｇｈｔｈｅｌｉｖｅｒ .Ｔｈｉｓｉｎｔｕｒｎｌｅａｄｓｔｏｄａｎｇｅｒｏｕｓ ｐｏｒｔａｌｈｙｐｅｒｔｅｎｓｉｏｎａｎｄｄｅｃｒｅａｓｅｄｍｅｔａｂｏｌｉｃｆｕｎｃｔｉｏｎｗｉｔｈｉｎｔｈｅｌｉｖｅｒ .Ｔｈｅｓｕｒｇｉｃａｌｔｈｅｒａｐｅｕｔｉｃｔｒｅａｔｍｅｎｔｓｎｏｗａｄａｙｓｃａｎ’ｔｓｏｌｖｅｔｈｅｐｒｏｂｌｅｍｓｕｃｃｅｓｓｆｕｌｌｙ .Ｔｈｅｄａｎｇｅｒｏｆｂ…

A PULSATION-TYPE PORTAL PUMP IN THE TREATMENT OF THE PORTAL HYPERTENTION

Objective In order to solve the problem of the de creased portal inflow, decreased metabolic function and dangerous varicosity in portal hypertension, a pulsation-type portal pump was prepared and used in the treatment experiment of canine model for portal hypertension, which was made by thread embolization in the portal vein. Methods Tow threads which were injected into the two branches of the portal vein would lead to portal hypertension after 2 weeks. A pulsation -type portal pump was made of a silica rubber balloon and a T-shaped silica ru bber tube. At the 2 tips of the T-shaped tube, two valves allowed the blood to flow in one direction. Two plates on both side of the balloon made the balloon p ulsate constantly. One plate made of stainless steel was fixed on one side of th e balloon while the other made of a piece of strong magnetic steel were fixed on the other side. The power was supplied by a low frequency alternating magnetic field that was placed outside the abdomen. The T-shaped tip of the pump was the n placed into the portal vein at the point above the major collateral branches. The blood pressure and flow of the portal system and the liver metabolic functio ns were measured. Results After pump working, the portal blood pressure above th e pump increased from (2.969±0.412)kPa to (4.802±0.696)kPa, whereas the po rtal pressure below the pump decreased from (3.077±0.301)kPa to (1.76 4±0.421)kPa,and the blood inflow of the liver increased from (0.270± 0.028)L*min-1 to (0.396±0.025) L*min-1. The pressure of the s plenic vein decreased from (3.548±0.392)kPa to (2.009±0.333)kP a and the pressure of the gastric fundal vein decreased from (3.459±0.323 )kPa to (1.891±0.461)kPa. The ICGK increased from (0.092±0.009 ) to (0.151±0.013) while the ICGR15 decreased from 19.03 ±8.50 to 9.04±2.50.Conclusion The pulsation-type portal pump significantly incre ased the blood inflow and the metabolic function of the liver, and decreased the blood pressure of the portal system. The design of the pump structure and the p ower supply were reasonable and skillful. More research work is needed to make t he pump to be placed safer and longer.