| CLONING AND EXPRESSION OF A GENE MEDIATING γ-RADIATION-INDUCED APOPTOSIS IN HL-60 CELLS |
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| 引用本文： | 李小明,宋天保,童新,孙志贤.CLONING AND EXPRESSION OF A GENE MEDIATING γ-RADIATION-INDUCED APOPTOSIS IN HL-60 CELLS[J].西安交通大学学报(英文版),2000,12(1). |
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| 作者姓名： | 李小明 宋天保 童新 孙志贤 |
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| 作者单位： | Department of Histology and Embryology,Xi'an Medical University,Xi'an 710061Molbiology Lab.,Beijing Institute of Radiation Medicine,Beijing 100850 |
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| 摘 要： | Apoptosis,orprogrammedcelldeath(PCD),isanintricatelyregulatedprocess">.Geneticstud-iesofapoptosisinCaenorhabditiseleganshavei-dentifiedced-3andced-4asproapoptoticgenesandced-9asanantiapoptoticgene"=-Severalmam-malianhomologuesofced-3,ced-4andced-9havebeenidentified.Recentstudiesindicatethatthefundamentalapoptosismachinery,whichconsistsofdistincteffectors,inhibitorsandinitiators,hasbeenconservedthroughoutevolution.Thekeyapoptosiseffectorsinmammalsareafamilyofcys-teine-containing,aspartate-spe…
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| 关 键 词： | γ-radiation apoptosis caspasa-3/CPP-32/Yama molecular cloning |
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