| THE STUDY OF POPULATION GENETIC RELATION AMONG TEN ETHNIC GROUPS IN NORTHWEST CHINA |
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| 作者姓名： | 康龙丽 金天博 陈腾 李生斌 |
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| 作者单位： | [1]StateKeyLaboratory,ForensicScienceDepartment,MedicalSchoolofXi＇anJiaotongUniversity,Xi＇an710061,China [2]StateKeyLaboratory,ForensicScienceDepartment,MedicalSchoolofXi＇anJiaotongUniversity,Xi＇an710061,China |
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| 基金项目： | ThisworkwassupportedbytheNationalNaturalScienceFoundationofChina(No.39970401). |
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| 摘 要： | Objective To investigate the genetic relation among ten ethnic groups in northwest China. Methods Allele frequencies of six STR(short tandem repeat) loci in D13S1358, VWA, FGA, D5S818, D13S317, and D7S820 were collected from Lasa Tibetan, Changdu Tibetan, Xi‘an Han, Gansu Dongxlang, Gansu Yugu, Xinjiang Uygur,Ozbak, Kirgiz, Sibe, Ningxla Hui by the results of State Key laboratory, Forensic Science Department, school of medical, Xi‘an Jiaotong University and internet biological information data bank, and compared with that of the Mongolian, Zhuang in China, and White and Negro in USA. The polymorphism index (H, DP, PPE, PIC) and genetic distance, then the phylogenetic tree of all population were reported. Results The resulting tree topology exhibited strong geographic and racial partitioning consistent with that obtained with HLA and classical genetic polymorphisms.Conclusion The results suggest that forensic STR loci may be particularly powerful tools and provide the necessary fine resolution for the reconstruction of recent human evolutionary history.
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| 关 键 词： | S820 HLA DP PIC STR VWA FGA |
THE STUDY OF POPULATION GENETIC RELATION AMONG TEN ETHNIC GROUPS IN NORTHWEST CHINA |
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| Kang Longli,Jin Tianbo,Chen Teng,Li Shengbin State Key Laboratory,Forensic Science.THE STUDY OF POPULATION GENETIC RELATION AMONG TEN ETHNIC GROUPS IN NORTHWEST CHINA[J].Academic Journal of Xi’an Jiaotong University,2004,16(2):171-173. |
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| Authors: | Kang Longli Jin Tianbo Chen Teng Li Shengbin State Key Laboratory Forensic Science |
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| Institution: | State Key Laboratory, Forensic Science Department, Medical School of Xi'an Jiaotong University, Xi'an 710061, China. |
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| Abstract: | Objective To investigate the genetic relation am on g ten ethnic groups in northwest China. Methods Allele frequ encies of six STR(short tandem repeat ) loci in D13S1358, VWA, FGA, D5S818, D13S 317, and D7S820 were collected from Lasa Tibetan, Changdu Tibetan, Xi'an Han, G ansu Dongxiang, Gansu Yugu, Xinjiang Uygur, Ozbak, Kirgiz, Sibe, Ningxia Hui by the results of State Key laboratory, Forensic Science Department, school of medi cal, Xi'an Jiaotong University and internet biological information data bank, a nd compared with that of the Mongolian, Zhuang in China, and White and Negro in USA. The polymorphism index (H, DP, PPE, PIC) and genetic distance, then the phy logenetic tree of all population were reported. Results The res ulting tree topology exhibited strong geographic and racial partitioning consist ent with that obtained with HLA and classical genetic polymorphisms. Conclusion The results suggest that forensic STR loci may be particular ly powerful tools and provide the necessary fine resolution for the reconstructi on of recent human evolutionary history. |
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| Keywords: | short tandem repeat (STR) ethnic groups genetic distance phylogenetic tree |
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