| THE PROTECTIVE EFFECTS OF THE TOTAL SAPONIN OF DIPSACUSASPEROIDES ON THE APOPTOSIS OF HIPPOCAMPAL NEURONSINDUCED BY β-AMYLOID PROTEIN |
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| 引用本文： | 钱亦华,杨杰,胡海涛,刘勇,杨广德,曹云新,任惠民.THE PROTECTIVE EFFECTS OF THE TOTAL SAPONIN OF DIPSACUSASPEROIDES ON THE APOPTOSIS OF HIPPOCAMPAL NEURONSINDUCED BY β-AMYLOID PROTEIN[J].西安交通大学学报(英文版),2004,16(1):30-34. |
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| 作者姓名： | 钱亦华 杨杰 胡海涛 刘勇 杨广德 曹云新 任惠民 |
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| 作者单位： | Department of Anatomy，Department of Anatomy，Department of Anatomy，Department of Anatomy，College of Pharmacy，The Laboratory of Flow Cytometer，Department of Anatomy Medical School of Xi'an Jiaotong University，Xi'an 710061，China，Medical School of Xi'an Jiaotong University，Xi'an 710061，China，Medical School of Xi'an Jiaotong University，Xi'an 710061，China，Medical School of Xi'an Jiaotong University，Xi'an 710061，China，XianJiaotong University，the Fourth Military MedicalUniversity，Medical School of Xi'an Jiaotong University，Xi'an 710061，China |
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| 摘 要： | Alzheimer sdisease(AD)isaneurodegenerativedisease ,whosehallmarksof pathologyaresenileplaques,βamyloidprotein (Aβ)depositionwith inbrain ,neurofibrillarytanglesformationandalotofneuronalloss .Thefactorsthatleadtoneuronallossareofcomplexityandmultiplicity ,includingthetoxicityofAβ,intracellularfreecalciumcon centrationhomeostasisimbalance ,damageofoxidefreeradicals ,andinitiationofmechanismofapop tosis,etal.1- 3] .Thedetailedmechanismhasnotreachedadefiniteconclusion .Thepreventionandtreat…
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| 关 键 词： | β-淀粉状蛋白 细胞培养 阿尔茨海默病 细胞凋亡 发病机制 |
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