INVESTIGATION ON RELATIONSHIP BETWEEN PREOPERATIONALSENSITIZATION AND CROSSMATCH |
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Authors: | Wang Bin FENG YiGuo XUE Wujun TIAN Puxun |
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Abstract: | Objective To explore the relationship between HLA sensitization and crossmatch and to assess its clinical value. Methods The subjects were divided into 3 groups :high sensitization group (PRA≥40%),low sensitization group (40%>PRA≥10%) and non-sensitization group (PRA<10%) according to the HLA antibody level detected by ELISA. The results of crossmatch were compared among the 3 groups. Results There was significant difference among the ratio of positive crossmatch in high sensitization group (39.4%),low sensitization group (10.5%)and non-sensitization group (2. 6%). Conclusion The sensitization level is positively correlated with the result of crossmatch. The improvement of matching precision can be made by using both of techniques mentioned above. |
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Keywords: | sensitization crossmatch renal transplantation |
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