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| RESORBABLE HIGH-STRENGTH ROD FOR FRACTURE INTERNAL FIXATION | |
| 作者姓名： | 杨团民 刘淼 杨爱玲 石宗利 邱希江 李毅 同志超 韩月 |
| 作者单位： | [1]DepartmentofOrthopaedics,FirstHospitalofXi＇anJiaotongUniversity,Xi＇an710061.China [2]People＇sHospitalofXunyiCounty,Xunyi711300,China [3]InstituteofMaterialandEngineering,LanzhouJiaotongUniversity,Lanzhou730070,China |
| 基金项目： | TheprojectwassupportedbytheNationalScienceFoundationofChina(No.39830100) |
| 摘 要： | Objective To find an ideal biomaterial for internal fixation. Methods Forty rabbits with fracture of the femur diaphysis (superioreondyle) were treated by intramedullary nailing of femur with composites rod of resorbable DL-polylactic acid (PDLLA)-ealcium metaphosphate (CMP), while steinmann‘s pin as control. The fracture healing, the material degradation and its mechanical properties were studied by X-ray films, macroscopic, microscopic and electron microscopic observations. Results No significant inflammatory reaction was found, and all the osteotomies were healed, while material was resorbed. Conclusion The PDLLA-CMP has excellent biocompatibility and mechanical properties, and it can be a promising implant material in orthopaedics surgery. |
| 关 键 词： | 偏磷酸钙 生物适合性 骨折愈合 DL-聚乳酸 PDLLA／CMP纤维合成 |
RESORBABLE HIGH-STRENGTH ROD FOR FRACTURE INTERNAL FIXATION |
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| Yang Tuanmin,Liu Miao,Yang Ailing,Shi Zongli ,Qiu Xijiang,Li Yi,Tong Zhichao,Han Yue.RESORBABLE HIGH-STRENGTH ROD FOR FRACTURE INTERNAL FIXATION[J].Academic Journal of Xi’an Jiaotong University,2004,16(1):58-61. | |
| Authors: | Yang Tuanmin Liu Miao Yang Ailing Shi Zongli Qiu Xijiang Li Yi Tong Zhichao Han Yue |
| Institution: | 1. Department of Orthopaedics, First Hospital of Xi'an Jiaotong University, Xi'an 710061,China 2. People's Hospital of Xunyi County, Xunyi 711300, China 3. Institute of Material and Engineering , Lanzhou Jiaotong University, Lanzhou 730070, China |
| Abstract: | Objective To find an ideal biomaterial for internal fixation. Methods Forty rabbits with fracture of the femur diaphysis (superiorcondyle) were treated by intramedullary nailing of femur with composites rod of resorbable DL-polylactic acid (PDLLA)-calcium metaphosphate (CMP), while steinmann's pin as control. The fracture healing, the material degradation and its mechanical properties were studied by X-ray films, macroscopic, microscopic and electron microscopic observations. Results No significant inflammatory reaction was found, and all the osteotomies were healed, while material was resorbed. Conclusion The PDLLA-CMP has excellent biocompatibility and mechanical properties, and it can be a promising implant material in orthopaedics surgery. |
| Keywords: | DL-polylactic acid(PLA) calcium metaphosphate(CMP) PDLLA/CMP fiber composites resorbable medical material fracture healing biocompatibility |
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