| A COMPREHENSIVE EVALUATION OF THE ROLE OF INHERITANCE AND ENVIRONMENTAL FACTORS IN PRIMARY LIVER CANCER |
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| 引用本文： | 王学良,徐慧文,程兵,门伯媛,刘蓬勃.A COMPREHENSIVE EVALUATION OF THE ROLE OF INHERITANCE AND ENVIRONMENTAL FACTORS IN PRIMARY LIVER CANCER[J].西安交通大学学报(英文版),1994(1). |
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| 作者姓名： | 王学良 徐慧文 程兵 门伯媛 刘蓬勃 |
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| 作者单位： | Department of Epidemiology，Xi'an Medical University，Xi'an 710061 |
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| 摘 要： | ＡＣＯＭＰＲＥＨＥＮＳＩＶＥＥＶＡＬＵＡＴＩＯＮＯＦＴＨＥＲＯＬＥＯＦＩＮＨＥＲＩＴＡＮＣＥＡＮＤＥＮＶＩＲＯＮＭＥＮＴＡＬＦＡＣＴＯＲＳＩＮＰＲＩＭＡＲＹＬＩＶＥＲＣＡＮＣＥＲＷａｎｇＸｕｅｌｉａｎｇ；ＸｕＨｕｉｗｅｎ；ＣｈｅｎｇＢｉｎｇ；ＭｅｎＢ...
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A COMPREHENSIVE EVALUATION OF THE ROLE OF INHERITANCE AND ENVIRONMENTAL FACTORS IN PRIMARY LIVER CANCER |
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| Wang Xueliang, Xu Huiwen, Cheng Bing, Men Boyuan,Liu Pengbo.A COMPREHENSIVE EVALUATION OF THE ROLE OF INHERITANCE AND ENVIRONMENTAL FACTORS IN PRIMARY LIVER CANCER[J].Academic Journal of Xi’an Jiaotong University,1994(1). |
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| Authors: | Wang Xueliang Xu Huiwen Cheng Bing Men Boyuan Liu Pengbo |
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| Abstract: | In 152 primary liver cancer (PLC)cases and 1: 1 matched controls, risk factors for PLC as well as relevent pedigree data were investigated. The results showed that in relatives of cases,PLC accumulative mortality was much higher than that in those of controls (0. 46% vs. 0. 07%, P< 0. 001 ). Of the cases, the rate in consanguineous relatives was 0. 55 %, but in non-consanguineous relatives it was 0. 08 % (P< 0. 01 ); and with alienating of consanguinity a regularly downward gradient of the rate could be observed ; in addition, an independent effect of inheritance remained significant when environmental factors were controlled by Logistic regression and stratification skill. And with an inheritance background, the role of some environmental factors as HBV infection, psychic trauma was reinforced significantly. These results provided further evidence for understanding the association between inheritance and PLC. |
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| Keywords: | primary liver cancer: inheritance background aetiology environmental factor casecontrol study |
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