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A NEW MODEL AND IMPROVED CABLE FUNCTION FOR REPRESENTING THE ACTIVATING PERIPHERAL NERVES BY A TRANSVERSE ELECTRIC FIELD DURING MAGNETIC STIMULATION
引用本文:于辉,郑崇勋,王海燕,王毅.A NEW MODEL AND IMPROVED CABLE FUNCTION FOR REPRESENTING THE ACTIVATING PERIPHERAL NERVES BY A TRANSVERSE ELECTRIC FIELD DURING MAGNETIC STIMULATION[J].西安交通大学学报(英文版),2005,17(1):6-9.
作者姓名:于辉  郑崇勋  王海燕  王毅
作者单位:Institute of Biomedical Engineering,Xi'an Jiaotong University,Institute of Biomedical Engineering,Xi'an Jiaotong University,Institute of Biomedical Engineering,Xi'an Jiaotong University,Institute of Biomedical Engineering,Xi'an Jiaotong University Xi'an 710049,China,Xi'an 710049,China,Xi'an 710049,China,Xi'an 710049,China
基金项目:ThisworkwassupportedbytheNationalNaturalScienceFoundationofChina(No.30170257).
摘    要:Theclassiccableequationhasbeenusedtore presenttheexcitationoflongandstraightperipheral nervesinanelectricfield.Itpredictsthatexcitation occursnearthemaximumofthenegativefirstspa tialgradient-E'‖=- Ex/ xinthedirectionofan x axialfiber1],whichisinagreem…

关 键 词:横向场  末梢神经  电缆方程  转移薄膜电位

A NEW MODEL AND IMPROVED CABLE FUNCTION FOR REPRESENTING THE ACTIVATING PERIPHERAL NERVES BY A TRANSVERSE ELECTRIC FIELD DURING MAGNETIC STIMULATION
Yu Hui,Zheng Chongxun,Wang Haiyan,Wang Yi.A NEW MODEL AND IMPROVED CABLE FUNCTION FOR REPRESENTING THE ACTIVATING PERIPHERAL NERVES BY A TRANSVERSE ELECTRIC FIELD DURING MAGNETIC STIMULATION[J].Academic Journal of Xi’an Jiaotong University,2005,17(1):6-9.
Authors:Yu Hui  Zheng Chongxun  Wang Haiyan  Wang Yi
Institution:Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an 710049, China
Abstract:Objective Previous studies of peripheral nerves activation during magnetic stimulation have focused almost exclusively on the cause of high external parallel electric field along the nerves, whereas the effect of the transverse component has been ignored. In the present paper, the classical cable function is modified to represent the excitation of peripheral nerves stimulated by a transverse electric field during magnetic stimulation. Methods Responses of the Ranvier nodes to a transverse-field are thoroughly investigated by mathematic simulation. Results The simulation demonstrates that the excitation results from the net inward current driven by an external field. Based on a two-stage process, a novel model is introduced to describe peripheral nerves stimulated by a transverse-field. Based on the new model, the classical cable function is modified. Conclusion Using this modified cable equation, the excitation threshold of peripheral nerves in a transverse field during MS is obtained. The modified cable equation can be used to represent the response of peripheral nerves by an arbitrary electric field.
Keywords:Transverse field  peripheral nerves  cable equation  trans-membrane potential
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