血清nCa2+含量在肾综合征出血热中的动态变化

目的 研究血清离子钙(nCa２＋)在肾综合征出血热(HFRS)中的变化规律及在发病中的作用。方法 用离子选择电极法检测了46例HFRS患者不同病期血清nCa２＋含量，并将nCa２＋与血清尿素氮(BUN)、肌酐(Cr)做相关分析。结果 HFRS患者在低血压休克期和多尿期时血清nCa2＋含量降低(P＜0..05)，以少尿期最为显著(P＜0..01)。而且随病情加重，结果依次降低，危重型患者整个多尿期也明显降低。血清nCa２＋含量与BUN、Cr呈负相关(P＜0.01)。结论 血清nCa２＋参与发病过程，与病情轻重和肾功状态密切相关。

The dynamic changes of serum ionized calcium in hemorrhagic fever with renal syn drome

Objective To study the regularity of the changes and the role of serum ionized Calci um in the pathogenesis of hemorrhagic fever with renal syndrome(HFRS). Methods Serum was detected at different stages of HFRS by selective electrode, and analized the relationship between serum with blood urea Nitrogen and creatinine. Results Serum was much lower (P＜0.05) during hypotension shock stage and diuretic stage, and significantly lower(P＜0.01) during oliguria stage. The decrease of serum level was correlated to the state of illness aggravated. There is a negative relativity between serum and blood urea Nitrogen and creatinine (P＜0.01) in the patients. Conclusion Serum levels in patients may be related to the severity of the disease and renal function.