陕西省黄陵县克山病病情15年调查报告

目的分析陕西省黄陵县1990-2004年克山病病情及相关因素的变化。方法以黄陵县克山病重病村观察点的全体居民作为调查对象,对全县范围内的慢型克山病(慢克)进行调查,并对观察点的发硒、粮硒水平进行动态观察。结果①观察点15年共检出潜在型克山病(潜克)447例次,检出率6.14%;新发潜克25例,新发生率34.34/万。②15年全县慢克确诊72例,先后死亡31例,病死率43.1%,其中20例死于慢性充血性心力衰竭,11例死于猝死。③观察点发硒与非病区比较无显著性差异,粮硒含量仍低于非病区。结论陕西省黄陵县观察点克山病的检出率呈缓慢上升趋势;潜克仍有新发;慢克病死率仍很高。

Fifteen consecutive years' investigation on Keshan disease in Huangling county of Shaanxi province

Objective To observe changes in conditions and the related factors of Keshan disease.Methods Surveillance site of Keshan disease conditions was set up in some villages in Huangling county where the disease occurred seriously and all the local residents were monitored for the past 15 years from 1990 to 2004.And chronic Keshan disease was observed all over the county.At the same time Selenium(Se) levels were measured in hair and cereal samples from local residents.Results ① Latent Keshan disease was diagnosed for 447cases.The diagnosed rate was 6.14%.New cases of latent Keshan disease ware diagnosed for 25 cases.The new incidence of latent Keshan disease was 3.434‰;② The diagnosed cases with chronic disease were 72 in 15 years,and 31 patients died.Motaility was 43.1%;③ The hair selenium contents in the endemic area of Keshan disease were not significantly different from those in non-endemic area.Conclusion The diagnosed rate of the disease is going up slowly.Latent Keshan disease has still occurred in this place.Motaility of chronic Keshan disease is still very high.