| 快速酶联免疫吸附试验诊断囊虫病的进一步研究——276例血清和脑脊液检测分析 |
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| 引用本文： | 张永浩,李小其,王健.快速酶联免疫吸附试验诊断囊虫病的进一步研究——276例血清和脑脊液检测分析[J].西安交通大学学报(医学版),1990(1). |
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| 作者姓名： | 张永浩 李小其 王健 |
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| 作者单位： | 西安医科大学寄生虫学教研室
(张永浩，李小其)，西安医科大学寄生虫学教研室(王健) |
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| 摘 要： | 用快速酶联免疫吸附试验检测276例脑囊虫病人血清或脑脊液、阳性率90%。囊液抗原与3例其他寄生虫病(牛带绦虫病、包虫病、肺吸虫病)的血清出现交叉反应,其光吸收值是0.28、0.31和0.33,抗体滴度在1:256以下;而囊虫病人血清光吸收值73.9%分布于0.5～1.5间,抗体滴度1:256～1:8192。囊虫病人脑脊液抗体滴度最高达1:16。12例囊虫病人经吡喹酮治疗后,1～2年內血清抗体转阴者仅1例(1/11),有1例治后4年未转阴。
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FOLLOW-UP STUDY OF DIAGNOSIS OF CYSTICERCOSIS BY RAPID ELISA——DETERMINATION AND ANALYSIS OF 276 CASES IN SERA AND CSF |
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| Zhang Yonghao,et al.FOLLOW-UP STUDY OF DIAGNOSIS OF CYSTICERCOSIS BY RAPID ELISA——DETERMINATION AND ANALYSIS OF 276 CASES IN SERA AND CSF[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(1). |
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| Authors: | Zhang Yonghao |
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| Institution: | Department of parasitology |
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| Abstract: | A total of 276 cases of neurocysticercosis were detected by rapid enzyme-Linked immunosorbent assay (Rapid ELISA), the positive rate was 90%, but there were 3 cases in other parasitic infective showed cross-reaction to cysticercus antigen(Taeniasis boris, Hydatidosis, Paragonimiasis), their absorbance were 0.28; 0.31; 0.33. The titer of antibody was below 1:256 in sera. But the distribution of the absorbance of cysticercosis in most patients was 0.5～1.5, the titers of antibody were 1:256～1:8192 in sera, but 1:8 was the highest in CSF. Therefore, the determination of CSF shoud be undiluted or 1:2 diluted. of 12 cases of cysticercosis after praziquantel treatment, the antibody levels in sera became nagative only in Ⅰ case during 1-2 years; One case remained positive after 4 years of treatment. |
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| Keywords: | Neurocysticercosis Rapid ELISA Antibody level in serum and CAF |
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