心肌梗塞时植物神经系统的作用及其临床意义

本文系统介绍关于心肌梗塞时植物神经系统作用方面的研究进展。心肌梗塞时交感一儿茶酚胺活性增高,副交感神经兴奋性也同时提高。前者可使梗塞范围扩大,心室功能下降加剧及心律失常发生率增加,而后者对心肌梗塞具有保护作用。文中详细叙述上述作用的病理生理机制,并联系说明临床使用β阻滞剂及阿托品的原理及其原则。此外,心室壁感受器反射是心肌梗塞发生时机体的一种保护性机制。

The Role of Autonomic Nervous System in Myocardial Infarcfion and It's Clinic Significance

The developement of recent researches about the role of autonomic nervous system in myocardial infarction (MI) was summed up Systematically. In case of MI there is a raise of cardiac Sympathetic-catecholamine activity and the parasympathetic exitibility also goes up. The former may extend the MI size,aggravate the cardiac function and increase the rate of arrythmia, while the later plays a protective role in MI.Their mechanisms were synthesized in detail and the clinic application of β-adrenergic receptor blocked and atropine in MI was mentioned. In addition, the enhancement of reflex elicited from ventricular receptors may be a protective mechanism in MI.