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腹腔外科感染的抗生素疗法
引用本文:潘承恩,于良,姚德茂,刘绍诰,赵中媛,高淑平.腹腔外科感染的抗生素疗法[J].西安交通大学学报(医学版),1991(4).
作者姓名:潘承恩  于良  姚德茂  刘绍诰  赵中媛  高淑平
作者单位:西安医科大学第一附属医院普通外科 (潘承恩,于良,姚德茂,刘绍诰),西安医科大学第一附属医院细菌室 (赵中媛),西安医科大学第一附属医院细菌室(高淑平)
摘    要:腹腔外科感染病人,抗生素疗法占有重要地位。252例腹腔脓液普通培养,24.2%无菌生长。培养出的菌丛中,绝大多数为革兰氏阴性细菌,大肠艾希氏菌占32.5%。选用抗生素应考虑:①菌丛及其联合存在的多样性;②药物进入胆汁的量与速度;③血与组织中的浓度;④药物的抗菌谱,毒性和价格。

关 键 词:外科感染  细菌  抗生素

ANTIBIOTIC THERAPY IN INTRA-ABDOMINAL SURGICAL INFECTION
Pan Chengen,Yu Liang,Yao Demao,et al Division of General Surgery.ANTIBIOTIC THERAPY IN INTRA-ABDOMINAL SURGICAL INFECTION[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1991(4).
Authors:Pan Chengen  Yu Liang  Yao Demao  Division of General Surgery
Institution:Pan Chengen,Yu Liang,Yao Demao,et al Division of General Surgery,Department of Surgery,First Affiliated Hospital
Abstract:For the majority of patients presenting withintra-adbominal surgical infection, antibiotic therapywill be the mainstary of treatment, The incidence ofnegative cultures on peritoneal suppurative fluid in 252patients with surgical infection is 24.2 per centGram-negative bacteria predominate in aerobes cul-tured on peritoneal pus. E, coli is 32.5 per cent in thesecases. In choosing an antibiotic or antibiotics for treat-ment of surgical infection of the abdomen. several fac-tors must be considered (1) the diversity of the organ-isms and their coexistence; (2) amount and velocit ofantibiotic excretion into bile and the effect of increasedbiliary pressures; (3) serum and tissue levels; (4)antibacterial spectrum, toxicity and cost.
Keywords:surgical infection bacteria  antibioties  
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