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新生儿脐血染色体观察(63例脐血染色体核型分析)
引用本文:吴霭如,卞双喜,林田.新生儿脐血染色体观察(63例脐血染色体核型分析)[J].西安交通大学学报(医学版),1981(3).
作者姓名:吴霭如  卞双喜  林田
作者单位:西医一院妇产科教研室 (吴霭如,卞双喜),西安医学院组织胚胎学研室(林田)
摘    要:1.对我院1980年4、5两月连续出生的63例新生儿脐血染色体核型初步进行了分析及讨论。共检出染色体数目异常及畸变6个,占所观察核型的0.635%与文献报导之发生率相近似。2.我们所作的新生儿脐血染色体核型分析仅为初期阶段,例数还不够多。报导的目的是希望能为西安地区染色体研究工作提出一个可供参考的常数资料。


Chromosom An lysis in 63 Newidorns
Abstract:A series of 63 cases of neonatal umbilical blood chromosome karyotype were analyzed during the period of April and May, 1980. The aim of this work is to find the spontaneous chromosome aberration occurring in the populatinn. It has been known that the condition of neonatalt chromosome would be the most uninfluenced comparing with the others. 63 newborns' umbilical blood were cultured with routine method and 1260 karyotypes were observed and analysed, in which 6 chromosome anomalies were fonud. The frequency of the overall aberration is 0.635%. Hyperploid is about 0.158%. Tetraploid is about 0.08%, chromatid break is about 0.08%. Chromosome gap is also 0.08%.The mothers of these 63 newborns were free from virus infections medicinal effects, radiative exposure or any other detrimental faclors during their pregnancy. Therefore, we considered that the result of this analysis may be used as basic values for the estimate of chromosomal research.
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