| 硒对克山病病区居民红细胞免疫功能的影响 |
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| 引用本文： | 张培毅,徐光禄,薛文岚,梁文升,张春明,葛克亮.硒对克山病病区居民红细胞免疫功能的影响[J].西安交通大学学报(医学版),1993(3). |
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| 作者姓名： | 张培毅 徐光禄 薛文岚 梁文升 张春明 葛克亮 |
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| 作者单位： | 克山病研究室微量元素与地方病研究实验室 西安 710061，克山病研究室微量元素与地方病研究实验室 西安 710061，克山病研究室，克山病研究室，克山病研究室，克山病研究室 微量元素与地方病研究实验室 西安 710061，微量元素与地方病研究实验室 西安 710061，微量元素与地方病研究实验室 西安 710061，微量元素与地方病研究实验室 西安 710061 |
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| 摘 要： | 给克山病病区14岁～16岁居民每日口服200μg亚硒酸钠硒或硒酵母硒12周后,测定血浆和红细胞硒含量以及红细胞C_(3b)受体花环率和免疫复合物花环率,以探讨补硒对病区居民红细胞免疫功能的影响。结果说明,补硒可使低硒人体血硒和红细胞免疫粘附功能增高;病区居民红细胞免疫功能低下与低硒有关;硒酵母硒提高血硒和红细胞免疫功能的作用比亚硒酸钠硒明显。
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| 关 键 词： | 克山病 红细胞免疫 补硒 |
EFFECTS OF SELENIUM ON ERYTHROCYTE IMMUNITY OF RESIDENTS IN A KESHAN DISEASE AREA |
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| Zhang Peiyi,Xu Guanglu,Xue Wenlan,et al Research Laboratory of Keshan Disease,Trace Elements and Endemic Diseases Research Laboratory.EFFECTS OF SELENIUM ON ERYTHROCYTE IMMUNITY OF RESIDENTS IN A KESHAN DISEASE AREA[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1993(3). |
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| Authors: | Zhang Peiyi Xu Guanglu Xue Wenlan Research Laboratory of Keshan Disease Trace Elements and Endemic Diseases Research Laboratory |
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| Abstract: | To investigate the effects of selenium (Se)supplements on the erythrocyte immunity of resi-dents in a Keshan disease area, residents aged 14～16 years were given orally 200 μg Se daily assodium selenite or Se-yeast for 12 weeks, andtheir plasma and erythrocyte Se contents and therosette formation rates of erythrocyte C_(3b) R andimmune complex were determined. The resultsshow that blood Se levels and the immunologic ad-herent function of residents with low-Se status areincreased after Se supplements, demonstratingthat the decreased erythrocyte immunologic func-tion is related to the low-Se status of the residentsin the affected area. When supplemented Se-yeast, the effect of Se is greater than selenite inenhancing blood Se levels and erythrocyte immuni-ty. |
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| Keywords: | Keshan disease erythrocyte immunity Selenium supplementation |
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