| 国产吡喹酮对家犬体内斯氏狸殖吸虫作用的组织化学与细胞化学观察 |
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| 引用本文： | 郑时春,张敏如.国产吡喹酮对家犬体内斯氏狸殖吸虫作用的组织化学与细胞化学观察[J].西安交通大学学报(医学版),1987(3). |
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| 作者姓名： | 郑时春 张敏如 |
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| 作者单位： | 西安医科大学寄生虫学教研室，西安医科大学寄生虫学教研室 |
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| 摘 要： | 本文报告吡喹酮对家犬感染的斯氏狸殖吸虫作用的组织化学与细胞化学观察结果。用药后24小时,虫体肌组织和实质组织内的糖原显著减少,肌肉RNA肠支内AKP也减少,卵黄腺内RNA、AKP均明显减少,而体壁内碱性蛋白质,卵黄腺内的酸性粘多糖和碱性蛋白质,表皮和肠支内ACP活动则明显增强。细胞化学观察证明用药后虫体表皮内的AKP消失。最后讨论了上述组织化学与细胞化学改变对吡喹酮杀虫作用的意义。
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HISTOCHEMICAL AND CYTOCHEMICAL OBSERVATION ON THE EFFECT OF PRAZIQUANTEL ON PAGUMOGONIMUS STRHABINI WORM IN DOGS |
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| Zheng Shichun Zhang Minru.HISTOCHEMICAL AND CYTOCHEMICAL OBSERVATION ON THE EFFECT OF PRAZIQUANTEL ON PAGUMOGONIMUS STRHABINI WORM IN DOGS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1987(3). |
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| Authors: | Zheng Shichun Zhang Minru |
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| Institution: | Department of Parasitology |
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| Abstract: | Histochemical and cytochemical changes of pagumogoniums skrjabini worms in dogs treated with praziquantel were observed relatively systernatically. Within 24 hours after treatment, the glycogen within the musculature and the parenchyma, RNA in the musculature and the vitellarium and AKP in the digestive tract and the vitellarium markedly decreased. Acid mucosubstances of the vitellarium,alkaline protient in the body wall and the vit- ellarium and ACP in the tegument and the ceca obviously increased. Transmission electron microscipe observations showed that AKP in the tegument disappeared. The effect of the histochemical aed cytochemical changes on the helminthicide is discussed. |
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| Keywords: | pagumogoniums skrjabini praziquantel histochemistry cytochemistry chemotherapy |
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