| 原发性肾病综合征患儿T细胞亚群及其抑制性细胞活性 |
| |
| 引用本文： | 牛余宗,王吉安,张京田.原发性肾病综合征患儿T细胞亚群及其抑制性细胞活性[J].西安交通大学学报(医学版),1990(4). |
| |
| 作者姓名： | 牛余宗 王吉安 张京田 |
| |
| 作者单位： | 西安医科大学第一附属医院儿科学教研室
(牛余宗，王吉安)，西安医科大学卫生系微生物学及免疫学教研室(张京田) |
| |
| 摘 要： | 本文检测了37例原发性肾病综合征患儿的外周血T淋巴细胞亚群和刀豆素A诱导的抑制细胞活性水平。结果显示,肾病患儿初发时就存在抑制性T细胞数量及功能的减低,并随着激素治疗及病情的好转而恢复正常,提示本病的免疫调节失衡可能是一原发性改变,在肾病发病机理中起一定的作用。
|
| 关 键 词： | 原发性肾病综合征 T淋巴细胞亚群 刀豆素A诱导的抑制细胞活性 |
THE STUDY OF T LYMPHOCYTE SUBSETS AND SUPPRESSOR CELL ACTIVITY IN CHILDREN WITH PRIMARY NEPHRITIC SYNDROME |
| |
| Niu Yuzong Wang Ji''''an,Zhang Jingtian.THE STUDY OF T LYMPHOCYTE SUBSETS AND SUPPRESSOR CELL ACTIVITY IN CHILDREN WITH PRIMARY NEPHRITIC SYNDROME[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(4). |
| |
| Authors: | Niu Yuzong Wang Ji'an Zhang Jingtian |
| |
| Abstract: | The peripheral blood T lymphocyte subsets and ConA-induced suppressor cell activity (ConA-SCA) were determined in 37 patients with primary nephritic syndrome(PNS). The results showed that the patients in initial onset had the abnormal number and function of T lymphocytes, which returned to a normal level with treatment with steroid and improvement of patients'condition. The indings suggest that the immunoregulatory imbalance of this disease may be a primary change and play an important role in pathogenesis of PNS. |
| |
| Keywords: | primary nephritic syndrome T lymphocyte subsets ConA-induced suppressor cell activity |
| 本文献已被 CNKI 等数据库收录！ |
