| 青藤碱对实验性心律失常的作用 |
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| 引用本文： | 孙芳云,郭惠玲,李西宽,赵东科,赵更生.青藤碱对实验性心律失常的作用[J].西安交通大学学报(医学版),1990(4). |
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| 作者姓名： | 孙芳云 郭惠玲 李西宽 赵东科 赵更生 |
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| 作者单位： | 陕西省咸阳民族学院药理学教研室，陕西中医学院药理学教研室，西安医科大学药理学教研室，西安医科大学药理学教研室，西安医科大学药理学教研室 进修生，进修生 |
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| 摘 要： | 本实验研究了青藤碱对实验性心律失常的作用。实验结果表明,青藤碱可缩短印防己毒素诱发家兔心律失常的持续时间;具有对抗BaCl_2诱发大鼠和CaCl_2-Ach诱发小鼠心律失常的作用;能使印防己毒素、BaCl_2、CaCl_2-Ach所致心律失常复转为窦性心律。并对缺血性心律失常有明显的对抗作用。
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| 关 键 词： | 青藤碱 心律失常 印防己毒素 |
THE EFFECT OF SINOMENINE ON EXPERIMENTAL ARRHYTHMIA |
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| Sun Fangyun,Guo Huiling Li Xinkuan,et al.THE EFFECT OF SINOMENINE ON EXPERIMENTAL ARRHYTHMIA[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(4). |
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| Authors: | Sun Fangyun Guo Huiling Li Xinkuan |
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| Institution: | Department of Pharmacology |
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| Abstract: | The effects of Sinomenine on experimental arrhythmia were studied. The result showed that Sinomenine could shorten the arrhythmetic period induced by picrotoxin in rabbit and protect rat against arrhythmia induced by BaCl_2. Sinomenine was found to recover the arrhythmia induced by BaCl_2-Ach into sinus rhythm in mice, Beside these Sinomenine also showed significant antagonising to ischemic arrhythmia. |
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| Keywords: | Sinomenine arrhythmia picrotoxin |
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