| 低硒大骨节病病区粮对大鼠软骨中组织蛋白酶D与碱性磷酸酶活性的影响 |
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| 引用本文： | 袁素芬,薛文岚.低硒大骨节病病区粮对大鼠软骨中组织蛋白酶D与碱性磷酸酶活性的影响[J].西安交通大学学报(医学版),1990(1). |
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| 作者姓名： | 袁素芬 薛文岚 |
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| 作者单位： | 西安医科大学生物化学教研室
(袁素芬)，西安医科大学克山病研究室(薛文岚) |
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| 摘 要： | 本文测定了低硒大骨节病病区粮对大鼠软骨溶酶体组织蛋白酶D与碱性磷酸酶活性的影响。结果表明,大鼠软骨溶酶体游离组织蛋白酶D及酶的总活性病区组均显著高于加硒组和西安组。大鼠软骨碱性磷酸酶活性病区组显著低于加硒组和西安组。
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| 关 键 词： | 组织蛋白酶D 碱性磷酸酶 溶酶体 软骨 大骨节病 |
EFFECTS OF THE LOW SELENIUM DIET IN THE KASHIN-BECK DISEASE AREA ON ACTIVITY OF CATHEPSIN D AND ALKALINE PHOSPHATASE OF CARTILAGE IN RATS |
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| Yuan Sufen.EFFECTS OF THE LOW SELENIUM DIET IN THE KASHIN-BECK DISEASE AREA ON ACTIVITY OF CATHEPSIN D AND ALKALINE PHOSPHATASE OF CARTILAGE IN RATS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(1). |
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| Authors: | Yuan Sufen |
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| Institution: | Yuan Sufen (Department of Biochemistry) Xue Wenlan (Research laboratory of Keshan Disease) |
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| Abstract: | Effects of the low selenium diet in the Kashin-beck disease area on activity of lysosomal cathepsin D and alkaline phosphatase of cartilage in rats were studied. The results of the experiments showed that the free type and total activities of lysosomal cathepsin D of cartilage in rats fed with low-selenium diet were higher than Selenium-supplemented group and Xi'an group. The acuvity of alkaline phosphatase in low-selenium group was lower than selenium-supplemented group and Xi'an group. |
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| Keywords: | Carthepsin D Alkaline phesphatase Lyscsome Cartilage Kashin-Beek disease |
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