| 特发性膜性肾病患者尿中足细胞与蛋白尿的相关性分析 |
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| 引用本文： | 尚瑜,尹爱萍.特发性膜性肾病患者尿中足细胞与蛋白尿的相关性分析[J].西安交通大学学报(医学版),2011,32(3):328-331. |
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| 作者姓名： | 尚瑜 尹爱萍 |
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| 作者单位： | 1. 西安医学院临床医学院内科学教研室,陕西西安,710021
2. 西安交通大学医学院第一附属医院肾病中心,陕西西安,710061 |
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| 基金项目： | 陕西省卫生厅科学研究基金资助项目 |
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| 摘 要： | 目的探讨特发性膜性肾病患者尿足细胞与尿蛋白之间的关系。方法选取40例特发性膜性肾病患者及30例健康人,采用独立样本t检验法比较试验组与健康对照组尿中足细胞的数、收缩压、舒张压、血清白蛋白、24 h尿蛋白量,并将试验组各项指标与尿足细胞作相关性分析,寻找与尿足细胞相关的因素。结果实验组患者尿足细胞数、尿蛋白水平明显高于健康对照组。Pearson相关分析显示试验组患者尿足细胞数与24 h尿蛋白量呈负相关,而与血压、血清白蛋白等指标无相关性。直线回归分析显示尿足细胞数和24 h尿蛋白量呈直线关系。结论特发性膜性肾病患者尿足细胞数较正常人升高,尿足细胞与24h尿蛋白量有一定的关系,尿足细胞数随着尿蛋白量的增加而减少。
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| 关 键 词： | 特发性膜性肾病 足细胞 蛋白尿 |
Correlation between urinary podocytes and urinary protein in patients with idiopathic membranous nephropathy |
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| SHANG Yu,YIN Ai-ping.Correlation between urinary podocytes and urinary protein in patients with idiopathic membranous nephropathy[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2011,32(3):328-331. |
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| Authors: | SHANG Yu YIN Ai-ping |
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| Institution: | SHANG Yu1,YIN Ai-ping2 (1.Section of Internal Medicine Teaching and Research,School of Clinical Medicine,Xi'an Medical College,Xi'an 710021,2.Department of Nephrology,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University,Xi'an 710061,China) |
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| Abstract: | Objective To explore the correlation between urinary podocytes and urinary protein in patients with idiopathic membranous nephropathy(IMN).Methods Totally 40 patients with IMN and another 30 healthy people were recruited.Independent sample t testing method was adopted to compare the test and control groups in terms of the number of urinary podocytes,diastolic blood pressure,systolic blood pressure,serum albumin and 24 h urine protein amount.The correlation of all the indicators from the test group with urin... |
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| Keywords: | idiopathic membranous nephropathy urinary podocyte proteinuria |
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