| 小儿急性肺炎血浆内皮素和尿表皮生长因子水平动态变化及临床意义 |
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| 引用本文： | 马珍奇,陈玺,郑纯礼.小儿急性肺炎血浆内皮素和尿表皮生长因子水平动态变化及临床意义[J].西安交通大学学报(医学版),1998(1). |
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| 作者姓名： | 马珍奇 陈玺 郑纯礼 |
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| 作者单位： | 西安第二临床医学院儿科!西安，710004，西安第二临床医学院儿科!西安，710004，西安第二临床医学院儿科!西安，710004 |
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| 摘 要： | 用放免分析法对37例急性肺炎病儿血浆内皮素（ET）及25例尿表皮生长因子（EGF）水平作了动态测定，结果肺炎急性期血浆ET及尿EGF含量明显高于对照组，差异显著（P＜0．01）。5例重症肺炎病儿血浆ET及尿EGF水平的急性期与恢复期自身对比观察，示其急性期血浆ET及尿EGF含量均明显高于恢复期，差异非常显著（P＜0．01）。两项指标在肺炎病程中呈正相关关系（P＜0．05）。提示：血浆ET及尿EGF含量在肺炎急性期的明显增高，对小儿肺炎的发生发展可能有一定促进作用。
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| 关 键 词： | 小儿急性肺炎 内皮素 表皮生长因子 |
CHANGES OF PLASMA ENDOTHELIN AND URINE EPIDERMAL GROWTH FACTOR IN CHILDREN WITH ACUTE PNEUMONIA AND THEIR CLINICAL SIGNIFICANCE |
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| Ma Zhenqi, Chen Xi, Zheng Chunli.CHANGES OF PLASMA ENDOTHELIN AND URINE EPIDERMAL GROWTH FACTOR IN CHILDREN WITH ACUTE PNEUMONIA AND THEIR CLINICAL SIGNIFICANCE[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1998(1). |
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| Authors: | Ma Zhenqi Chen Xi Zheng Chunli |
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| Abstract: | The concentrations of plasma endothelin (ET ) in 37 cases and urine epidermal growth factor(EGF) in 25 cases of acute pneumonia were dynamically observed by radioimmunoassay.Results: amounts of ET and EGF for pnenmonia at acute phase were statistically higher than those of controls(P＜0. 01) ; ET and EGF levels of 5 severe pneumonic children in acute and restorative stages were respectively investiguted, and those values above were significantly higher in acute stage than in restorative stage(P＜0. 01). We also found the positive correlation between ET and EGF in the same stage of these cases(P＜0. 05). Conclusion:ET and EGF amounts in acute stage of pneumonic children were siedficantly elevated, which perhaps accelerates the genesis and development of pneumonia. So these indexes may help us to juge the prognosis. |
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| Keywords: | acute pneumonia endothelin epidermal growth factor |
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