| 大鼠海马血管代谢的组织化学研究 |
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| 引用本文： | 姬西团,周敬德,赵根然,马兆龙,刘勇.大鼠海马血管代谢的组织化学研究[J].西安交通大学学报(医学版),1990(3). |
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| 作者姓名： | 姬西团 周敬德 赵根然 马兆龙 刘勇 |
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| 作者单位： | 西安医科大学人体解剖学教研室
(姬西团，周敬德，赵根然，马兆龙)，西安医科大学人体解剖学教研室(刘勇) |
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| 摘 要： | 本文用组织化学方法,选择能反映血管壁糖代谢3个途径及平滑肌能量利用的5个关键酶,在同一显微镜下对正常SD系不同月龄组大鼠海马血管的酶代谢进行了半定量研究。结果为乳酸脱氢酶活性随着大鼠月龄及血管口径的增加而增强,琥珀酸脱氢酶及细胞色素氧化酶示轻度反应,葡萄糖—6—磷酸脱氢酶呈轻度至中度活性,钙激活三磷酸腺苷酶在动脉及微动脉示极强阳性,静脉示强阳性,毛细血管呈中度至强阳性。讨论了海马血管壁代谢酶的变化与海马血管病的关系。
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| 关 键 词： | 海马血管 酶组织化学法 大鼠 |
A HISTOCHEMICAL STUDY ON METABOLISM IN THE WALLS OF AGING RATS' HIPPOCAMPAL VESSELS |
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| Ji Xituan,et al.A HISTOCHEMICAL STUDY ON METABOLISM IN THE WALLS OF AGING RATS'''' HIPPOCAMPAL VESSELS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(3). |
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| Authors: | Ji Xituan |
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| Institution: | Department of Anatomy |
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| Abstract: | We investigated five enzymes of three metabolic pathways and an index of utilization of generated adenosine triphosphate of smooth muscular contraction. Five enzymes in the vessel walls were seniquantitatively evaluated in the aging rats(SD), Using histochemical method and bright-field microscopy. Lactate dehydrogenase showed significant reactivity which increased with vessel diameter and age in hippocampus. Succinate dehydrogenase and cytochrome oxidase showed little reactivity in hippocampal vessel in all age groups tested. Glucose-6-phosphate dehydrogenase reaction showed slight to moderate reaction. Myosin ATPase reactivity was high in the hippocampal vessels, arteries and arterioles showed very strong reaction, veins showed strong reaction, capillary showed moderate to strong reaction. And then we discussed the relationship between vascular disease and these enzymes in hippocampus. |
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| Keywords: | hippocampus vessls enzyme histochemical method rats |
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