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1.
Kashin- Beck Disease (KBD) is an endemicchronic osteoarthropathy affecting about2 .5mil-lion residents with over30 millions at risk in Chi-na[1] .The disease is mainly distributed in a distinctwide beltwith low selenium running obliquely fromthe Northeast to the Southwest of China.Most ofthe inhabitants in areas with KBD are in low seleni-um nutrition status resulting in low selenium con-tent in hair,blood and urine[2 ] .Biochemical studiesshowed that hydroxyproline in urine of childrenwi… 相似文献
2.
EFFECTSOFCEREALSFROMKASHIN-BECKDISEASEENDEMICAREAONFIBRILLOGENESISINVITROOFCARTILAGECOLLAGENTYPEⅡINRATSFuZhihou;ZhangShiyuan(... 相似文献
3.
STUDY ON THE EFFECT OF T-2 TOXIN AND SELENIUM ON CD44 EXPRESSION IN THE CULTURED HUMAN FETAL CHONDROCYTES IN VITRO 总被引:1,自引:0,他引:1
KBD (Kashin BeckDisease)isasevere ,en demicosteoarthrosisandthepathogenesisofitisstillapendentproblem[1] .WiththestudyofetiologyofKBD ,thehypothesisofselenium deficiencyinthesurroundingandfoodcontaminatedbyfungaltoxinisanoticeableone .The pathologicalfeaturesofKBDarethedegenerationandnecrosisofthearticu larcartilage ,disorderofmetabolismofcartilagematrix .Thestudyontheosteoarthrosissuggeststhatthereductionoftheaggregationandincreaseofdeg radationofaggrecanareinitialaffairsifcartilagehasdeg… 相似文献
4.
Kashin BeckDisease(KBD)isasevere,en demicosteoarthrosis,butitspathogenesisisstilla pendentproblem.Withregardtoetiologyanalysis,mycotoxinhypothesisandlow seleniumhypothesis havebeenstudiedmoreinChina[1].Thepathologi calfeaturesofKBDarethedegenerationandnec… 相似文献
5.
EFFECTOFCO-SUPPLEMENTATIONOFVITAMINEANDSELENIUMONNORMALANDMALIGNANTCELLPROLIFERATIONHuWenliang;LiuLihua;AnthonyTDiplock.(Depa... 相似文献
6.
InordertoinvestigatethemechanismofidiopathicPerthesdisease,alotoftheorieshavebeenproposed.Butmostofthemlaidparticularemphasisontheosteopathology,hemorrheology,biomechanicsandchondropathology',.,'.Therehasbeenfewstudyonthechondricfunction,biochemicalchangeandit'srolesinidiopathicPerthesdisease.Generallythebiochemicalchangesofcartilageareinitialalterationinboneandjointaffection.Therefore,wecarriedoutthisstudytodetecttheproteoglycancontentinaffectedcartilageandHAlevelsinsynovialfluidandserumand… 相似文献
7.
AngiotensinⅡ (AngⅡ ) playsanimportantroleintheregulationofbloodpressure[1 ] .Theac tionofAngⅡismediatedmainlybystimulationoftheangiotensintype 1(AT1 )receptorandinvolvesintheactivityofcatecholaminergicsystem .Im munostainingstudieshaveindicatedthattheAT1 re ceptorexistsonthecatecholaminergicneurons[2 ] .AdministrationofAngⅡintorat’sbrainincreasedtheconcentrationsofdopamine ,epinephrine ,andnorepinephrineinthebrain[3 ] .Althoughanatomicalandfunctionalevidencessupporttheinteractionbe twe… 相似文献
8.
Resveratrolhasbeenfoundinmanyplantsandhasalotofvaluableeffectsuchasanti tumor,anti inflam mation ,treatmentofcardio vasculardiseases[1] .Themechanismisrelatedtothequenchingoflipidperoxida tion[2 ,3] .Manypapersreportedthatresveratrolwasex tractedfromgrape .Howev… 相似文献
9.
EFFECTOFSIBELIUMONHYPOXICCULTUREDNEURONSFROMNEWBORNRATSCEREBRALCONTEXINVITRO(刘小红)(陈征起)(和光祖)LiuXiaohong;ChenZhengqi;HeGuangzu;... 相似文献
10.
Kashin BeckDisease(KBD)isachronic ,trans formative ,endemicosteoarthrosis ,pathologicallycharacterizedbychondrocytenecrosisofjointcarti lagedeeplayerandepiphysealplatecartilagehyper trophiclayer .Duringthecourseofetiologystudy ,manyscholarshavefoundthatimmunedisorderdoexistin patientswithKBD ,forexample ,the“DLD”(Death Life Death) phenomenoninchon drocytenecrosisandnecrolysis ,andthe“chondro cytegobbets”responses .Sincethe 1980 ,immunestatusofKBDwasfitfullyinvestigated .Acommonconcl… 相似文献
11.
EFFECTOFIRONSUPPLEMENTONSERUMLEVELSOFT3,T4,TSH,GHANDINSULININCHILDRENWITHIRONDEFICIENCYXiaoYanfeng;YinJing;ZhengChunli;(Departme... 相似文献
12.
Traceelementsareimportantnutri-tioussubstancesforgr0wthofchildren.Ithasbeenrep0rtedthatzincdeficiencyisthecause0fgrowthretardation,dwarfisminchildren.Thec0rrelation'0flevel0fzinc,calciumwiththegr0wthofhealtllychildren,howeverFasn0tbeenclearlyin-vestigated.Inthispaper,thecorrelationofheightandweight0fchildrenwithzinc(Zn),calcium(Ca)statusisanalysedandtheeffect0fzincsupplementongrowthofchildrenisinvestigated,accordingt0anobservati0n0n456healthychildrenaged3~6yearsinXi'an.MATERIALSANDMET… 相似文献
13.
EFFECTS OF CHRONIC STRESS ON THE ACTIVITIES OF SOD, GSH-Px AND MDA LEVEL IN FEMALE RATS‘ BRAIN 总被引:1,自引:0,他引:1
“CityStressSyndrome” ,suchasanxiety ,memoryrecessionandneurasthenia ,isbecominga globalphenomenon .O’Brienreportedthat prolongedstressmightcause permanentbraindamage[1] .Quervain’sresearchesindicatedthatchronicstresscouldimprovememorydeficiencymediatedbyhipp… 相似文献