THE PROTECTIVE EFFECTS OF THE TOTAL SAPONIN OF DIPSACUSASPEROIDES ON THE APOPTOSIS OF HIPPOCAMPAL NEURONSINDUCED BY β-AMYLOID PROTEIN

Alzheimer sdisease(AD)isaneurodegenerativedisease ,whosehallmarksof pathologyaresenileplaques,βamyloidprotein (Aβ)depositionwith inbrain ,neurofibrillarytanglesformationandalotofneuronalloss .Thefactorsthatleadtoneuronallossareofcomplexityandmultiplicity ,includingthetoxicityofAβ,intracellularfreecalciumcon centrationhomeostasisimbalance ,damageofoxidefreeradicals ,andinitiationofmechanismofapop tosis,etal.[1- 3] .Thedetailedmechanismhasnotreachedadefiniteconclusion .Thepreventionandtreat…     

OVERALL CONTENTS OF THE VOLUME

A Solution Model to Protect Mobile Agents Against Malicious Host AttackJulius M.T.Rwakarambi(迈克尔 ) ,XU L iang- xian(徐良贤 )　 (1)……………………………………………………A New Schem e of Integrating NAS with SAN WAN G Zhi- heng(王志恒 ) ,BAI Ying- cai(白英彩 )　 (6 )…………………A Dynam ic Job Scheduling Algorithm for Parallel SystemZH AN G Jian(张　建 ) ,L U X in- da(陆鑫达 ) ,Mohammed A.M.Ibrahim(加　力 )　 (10 )……………………………Fair Preorder for Partial Fair …     

ON THE EXISTENCE OF THE h-RESTRICTED EDGE CONNECTIVITY OF A GRAPH

IntroductionLet G=(V,E) be a finite,simple and undi-rected graph with vertex set V and edge set E.We' ll follow the terminology and notation of Ref.[1 ]and terms not defined here can be found inRefs.[1 ,2 ].A set S of edges of G is called an edgedisconnecting set if G - S is disconnected. Theusual edge connectivityλ(G) of G is the minimumcardinality over the all edge disconnecting sets ofG.Note that,in the above definition,absolutelyno conditions or restrictions are imposed either onthe…     

ONE PROBABLE MECHANISM OF THE LEARNING-MEMORY DAMAGE BY LEAD:THE CHANGES OF NOS IN HIPPOCAMPUS

Leadtoxicityremainsapublicproblemintheworld ,especiallyinthedevelopingcountries.Chronicleadexposurecancauseimpairmentofcog nitivefunctionandsignificantdelaysinbehavioraldevelopment.However ,themechanismsunderly ingtheseimpairmentshavenotbeendefined .Long term potentiation (LTP)isthoughttobeavalidmodeloflearningandmemoryatthelevelofthesynapse[1] .Recently ,nitricoxidesynthase (NOS)hasbeenshowntobeanimportantfactorforforma tionandlastingofLTP[2 ,3 ] .Theremightbesomerelationsamonglead ,LTP…     

THE EFFECT OF EXOGENOUS SURFACTANT ON THE EUSTACHIAN TUBE FUNCTION IN THE GERBIL MODEL OF SECRETORY OTITIS MEDIA

Secretoryotitismedia (SOM )isacommondis easeandasignificantworldhealth problem .Al thoughSOMiswellrecognizedatclinicallevel,itspathogenyispoorlyknown .Theeustachiantubeservesanimportantfunc tioninequalizingpressurebetweenthemiddleearandthenasopharynx .Theeustachiantubeinthenormalstateisclosed ,butintermittentlyopensbytheactionofthetensorvelipalatiniandlevatorvelipalatinimusclesduringswallowing .Absenceofsurfactantoneustachiantubeisoneofimportantreasonsoftheirdysfunction .Thisre searchinject…     

MUTATION OF THE ENDOTHELIN-B RECEPTOR AND THE ENDOTHELIN-3 GENE IN CHINESE SPORADIC CASES OF HIRSCHSPRUNG''''S DISEASE

Hirschsprung’sdisease (HD)isacongenitalmalformationwithanincidenceofonein 50 0 0livenewborns .Theabsenceofintramuralintestinalgan gliaofMeissnerandAuerbachresultsinpoorcoor dinationofpropulsivemovementandhencefunc tionalintestinalobstruction .Patientsaretreatedsur gicallywithremovaloftheaffectedintestine[1 ] .In1994 ,twomajorgenesassociatedwithHDwererecognized .First ,intheRET (Receptortyrosinki nase) gene,thereareinactivatingmutationsiniso latedHD .RETaccountsforupto 2 0 %ofsporadicand…     

THE INHIBITORY EFFECT OF MELATONIN ON THE GROWTH OF HUMAN BLADDER CARCINOMA T24 CELL LINE

Melatonin(Mel) ,anindoleamineprimarilyderivedfromthepinealgland ,issecretedduringthehoursofdarkness.Melactsasahormonalconduc tionof photoperiodinfluencedbytheseasonanddailyphysiologicalrhythms.Thefunctionofmelinhumansisobscure .However ,melhasattainedprominenceasatreatmentfordisturbedcircadianrhythmsandsleeppatterns ,hasenhancedthefunc tionofimmunitysystem[1] andhasinhibitedtumorgrowth[2 ] .Thepreviousstudieshaveindicatedthatmelcombinedwithotheranticancerdrugscanin creasetheefficiencyanddecre…     

ALTERATION OF HB-EGF IN PSORIATIC EPIDERMIS WITH THE TREATMENT OF RETINOID ACID

Retinoidacid (RA)bindingtoitsnuclearre ceptorscouldexertawidevarietyofprofoundef fectsininhibitingproliferationofepidermis ,induc ingdifferentiation ,maintainingthemorphologicalfeatureofnormaltissues ,influencingblastocystde velopment,formationoforgansandtumors .Psori asisischaracterizedbyabnormalkeratinocyteprolif eration ,terminaldifferentiationanddermalangio genesis .Heparinbindingepidermalgrowthfactor likegrowthfactor (HB EGF) ,asamemberofepi dermal growthfactor (EGF )family ,hasbeenpr…     

DEVELOPMENT OF NEW TYPE OF HAZARDLESS FLUXES USED IN THE MELTING OF Mg-ALLOYS

lIntroductionMagnesium,oneofthelighteststructurematerials,hasbeenwidelyappliedinaviation,machineryandautomobilemanufacturing.Withstrongaffinitytooxygenandporosityofitsoxidefilm,magnesiumisapttoreactwithoxy-gen.Thus,duringthemeltofmagnesiumalloys,specialfluxeshavetobeusedtocoverthemelttokeepitfromfurtheroxidizationorevencom-bustionathightemperature,andtorefineandtodegasitandtoremovethedrossfromthemelt[1j.Thewidelyusedfluxesaremainlycomposedofwaterlesscarnallite(MgCl,-KCl)andsomefluoridesandch…     

DAMAGES OF GYPENOSIDES ON THE ULTRASTRUCTURES OF S-180 SARCOMA IN MOUSE

Gypenosides(GP)wasextractedfromGynostemmapentaphyllam(Thunb.)Markc17.LiteraturereportandourlaboratorystudiedresultsshowedthatGPhadsignificantinhibitionactiontomanykindsoftumorstraint23.InordertorevealthemechanismofantitumorofGP,westudiedtheeffectsofGPontheultrastructureofS--180sarcomacellsinmouse.MATERIALSANDMETHODSKun-iningspeciesmouse,weighing22t2g,eithersex,injecteds.c.0.2ml(contained4X105cells)cellsuspendingsolutionofS-180sarcoma,wasrandomizedintofourgroups:Salinecontrol(n'30…     

THE ROLE OF RED NUCLEUS IN THE MODULATION OF SPINAL NOCICEPTIVE TRANSMISSION AND IN NOCICEPTION ELICITED BY MUSCLE SPINDLE AFFERENTS

RNiswellknownasanimportantnucleusinmotorcontrolofextra pyramidalsystem .However ,anatomicalstudieshaverevealedthatasignificantproportionoftherubrospinalfibersterminatesintheventralportionofthedorsalhorn (laminaeⅤ Ⅵ ) ,andinpartoftheintermediatehorn (laminaeⅦ ) .Suchterminaldistributionsuggestthatrubro spinalneuronsmaymodulatetheresponsesofdorsalhornneuronsinvolvedintherelayofsomatosensorycutaneousinformationtomorerostrallevelsofner voussystem .ThereareevidencesthatRNstimula tionaffectsnoc…     

ACETYLCHOLINESTERASE HISTOCHEMISTRY OF THE THALAMUS IN THE PRIMATE

Ａｃｅｔｙｌｃｈｏｌｉｎｅｓｔｅｒａｓｅ(ＡｃｈＥ)ｉｓａｈｙｄｒｏｌｙｔｉｃｅｎｚｙｍｅｗｉｔｈｅｘｔｅｎｓｉｖｅｄｉｓｔｒｉｂｕｔｉｏｎｉｎｔｈｅｃｅｎｔｒａｌｎｅｒｖｏｕｓｓｙｓｔｅｍ ,ａｎｄｉｔｈａｓｆｒｅｑｕｅｎｔｌｙｂｅｅｎｕｓｅｄａｓａｃｈｅｍｉｃａｌｍａｒｋｅｒｆｏｒｔｈｅｓｔｕｄｙｏｆｐｒｅｓｕｍｅｄｃｈｏｌｉｎｅｒｇｉｃｓｔｒｕｃｔｕｒｅｓｉｎｂｒａｉｎ .Ｔｈｅｌｉｔｅｒａｔｕｒｅｓｒｅｐｏｒｔｅｄｔｈａｔｔｈｅｒｅｗａｓａｃｌｏｓｅｒｅｌａｔｉｏｎｓｈｉｐｂｅ ｔｗｅｅｎｔｈ…     

THE COLONIC TRANSIT TEST IN THE ASSESSMENT OF CHRONIC CONSTIPATION

In order to assess colonic motility of chronic constipation, colonic transit test was carried out in 34 patients with chronic constipation and in 20 healthy subjects. 20 radiopaque markers are ingested at 8 am before the day test, and plain abdominal films were obtained at 24 h, 48 h and 72 h. The normal value of colonic transit test was 16(80%), or more markers passed after 72 h. By means of transit time study, 34 constipated patients were classified into 2 groups: 12 normal transit patients and 22 slow transit patients. There was no difference in colonic transit time between normal transit patients and controls (P＞0.05). Patients with slow transit had more markers left in right colon, left colon and rectosigmoid colon at 48 h (P＜0.01, respectively) and 72 h (P＜0.01, respectively). According to the transit index, 22 slow transit patients were divided into 3 types: 10 cases colonic stasis, 8 cases outlet obstruction and 4 cases colorectal stasis. The study suggests that chronic constipated patients have abnormalbilities of colonic transit.     

OVERALL CONTENTS OF THE VOLUME

RobustStabilityandPerformanceComparisonofPIDandPPIControlRENZheng-yun(任正云),ZHANGHong(张　红),SHAOHui-he(邵惠鹤)　(1-1)……………………………Control-RelevantIdentificationTestDesignforOpen-LoopExperimentZHANGLi-qun(张立群),SHAOHui-he(邵惠鹤)　(1-6)……………………………………………………………PredictionofWeldingDeformationofUnderframeCHENJun-mei(陈俊梅),LUHao(陆　皓),WANGJian-hua(汪建华),etal　(1-10)……………………………TechnologyProblemsofLaserCladdingProcedurefori…     

OVERALL CONTENTS OF THE VOLUME

Overlay Share Mesh for Interactive Group Communication with High Dynamic……………………………………WU Yan-hua(吴言华), CAI Yun-ze(蔡云泽), XU Xiao-ming(许晓鸣) ( 1 - 1 )Efficient Protocol-Proving Algorithm Based on Improved Authentication Tests……………………………LI Xie-hua(李谢华), YANG Shu-tang(杨树堂), LI Jian-hua(李建华), et al ( 1 - 9 )A Target-Orientated Marker Image Binarization Method for Orthopaedic Surgical Navigation System………………………YAN Shi-ju(闫士举), …     

THE NINTH EDITORIAL BOARD OF JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY

Chairman XIE Sheng-wu (谢绳武)Vice Chairmen LIN Zhong-qin (林忠钦)ZHANG Wen-jun (张文军)PENG Ying-hong (彭颖红)Editor-in Chief ZHENG Hang (郑 杭)Associate Editor-in-chief GONG Han-zhong (龚汉忠)TAO Shi-di (陶世弟)FANG Hua (方 华)Members ZHANG Sheng-kun (张圣坤) SHEN Wei-ping (沈为平) LIU Xi-la (刘西拉)MIAO Guo-ping (缪国平) LU Chuan-jing (鲁传敬) YANG Jian-min (杨建民)SHEN Hui-shen (沈惠申) XU Jin-quan (许金泉) MENG Guang (孟 光)CAO Xue-wu (曹学武) HUANG Z…     

STUDY ON THE INITIATION AND PROPAGATION OF REHEAT CRACK

11ntroductionTherearestilldifferentviewpointsaboutthemechanismofreheatcracking(alsocalledstress-reliefcrack)inrecentyears.Somescien-tiststhinkthatreheatcrackingismainlycausedbyprecipitationstrengtheningrainduringstress-relieftreatment.Somestressthatreheatcrackingismainlyresultedfromtheintercrystal-linesegregationofsomeharmfulelementswhichmaycauseintercrystallinebrittleness.Andmoreothersprefertoexplaintheinitiationofreheatcrackingwithcreeptheory.Thetheoryaboutcreepruptureincludesstressconcentra…     

IMPROVING THE INTERESTINGNESS OF WEB USAGE MINING

IntroductionWeb usage mining is the application of datamining to the web server's log in order to discoverthe behavior patterns of the web site visitors.Thebehavior patterns found should be highly interest-ing.That is,they should be valid,novel,poten-tially useful,and ultimately understandable[1] .Finding frequently visited page groups is animportant topic in web usage mining.Intuitively,the frequently visited page group ( FVPG) is a setof web pages thatare often requested together by anumbe…     

THE OPTIMALITY CONDITION AND DUALITY OF MULTIOBJECTIVE POSYNOMIAL GEOMETRIC PROGRAMMING

1IntroductionSinceitsinceptionbyZener[1'2JandDuf-fin[3.'1,geometricprogramminghasundergonerapiddevelopment,especiallyaftertheappear-anceofthefirstbookonthesubject['j.Multiob-jectivemathematicalprogrammingisalsoafast-developingsubject.Therehavebeenmanyachievementsinboththeoreticalandappliedas-pects['~'].Considerthemultiobjectiveprogrammingproblem:whereXcrR"(n>l)isaconstraintsetandf:X-R-(m>2)avectorobjectivefunction.WriteR7=(v6R'lv>o}iandletxbeasdefinedaParetoefficientsolutionof(VMP)ifxeXa…