双洎河渡槽动力特性分析

本文使用大型有限元分析软件ANSYS对双洎河渡槽的动力特性进行计算,分别采用了Westergaard方法和Housner方法来模拟水体,计算了在两种水深情况下渡槽动力特性,得出了水深对渡槽动力特性的影响结果,分析了Westergaard方法和Housner方法的差异。所得结果可为该大型渡槽的抗震设计提供依据。     

宣武门地铁车站群洞施工技术及沉降分析

结合地铁四号线宣武门车站的施工,介绍了PBA洞桩法施工的关键技术,对浅埋暗挖群洞施工引起的沉降情况进行了分析,提出控制地表沉降的有效方法,为类似施工工法提供借鉴。     

5S在集装箱码头现场管理中的应用

世界各国的集装箱码头在如何提高作业效率和降低事故发生率方面都面临着巨大的挑战。高效率、低事故发生率是每个集装箱码头生产管理所追求的的目标。而将5S管理应用到集装箱码头的现场生产管理中,定会达到理想的效果。 5S起源于日本.是指在生产现场中通过整理、整顿、清扫、清洁和修养等5项操作要求对人员、机械、工艺等生产要素进行有效管理,从而起到改善生产环境、降低生产成本、提高作业效率、鼓舞员工士气、保证安全生产的作用。由这5项操作要求日语原文,用拉丁字母表示拼音时,都以“S”为首字母,所以统称为5S管理。     

光纤直放站的设计与施工

新长铁路北起江苏省北部的新沂市并与陇海铁路接轨，南至浙江省的长兴县与宣杭铁路接轨，全长638km，采用数字无线集群解决调度及公务通信。图1为新长线无锡西-长兴段数字无线集群系统构成图。在新长铁路中设置有武进、宜兴北、丁山、夹蒲4个基站，宜兴、无锡西2个直放站。但由于江浙两省交界处为山区丘陵地形，基站覆盖困难，需要在弱场强区段的麒麟山隧道、K140处设置光纤直放站达到场强覆盖，解决通信盲区问题。[第一段]     

地基土抗剪强度与极限平衡条件的评价分析

在确定地基土的抗剪强度的基础上 ,运用材料力学中平面应力状态的理论对无粘性土和粘性土均进行了极限平衡条件的评价分析 ,运用该分析方法进行工程实例计算 ,计算结果表明该方法较准确、可靠。     

Distribution of nitric oxide synthase, nerve growth factor receptor and interstitial cells of Cajal in hirschsprung's disease and its significance

Objective To investigate the distribution of nitric oxide synthase (NOS), nerve growth factor receptor (NGFR) and interstitial cells of Caial (ICCs) in Hirschsprung's disease (HD). Methods The distribution of NOS,NGFR and ICCs was studied by using NADPH diaphoruse histochemistry, immanohistochemistry with a monoclonal antibody to human NGFR and the specific polycloual antibody against c-kit in 8 normal controls and 10 cases of HD.Results NOS and NGFR were abundantly present in the myenteric plexus and in the nerve fibers of musculature. ICCs were intensively distributed in the surface of circular musculature and around the myenteric plexus to form a network in normal control colon. In contrast, NOS and NGFR were scarce or absent in the myenteric plexus and in the nerve fibers of musculature, while the hypertrophic nerve trunks were NGFR positive, ICCs were scarcely distributed and the network was disrupted in the aganglionic colon in HD. Conclusion These findings suggest the Involvement of NOS,NGFR and ICCs in the patbophysiology of HD.     

基质金属蛋白酶-2及其抑制因子TIMP-2 在脑胶质瘤中的表达及意义

目的探讨基质金属蛋白酶-2(MMP-2)及其抑制因子TIMP-2的表达及其与脑胶质瘤恶性程度之间的关系。方法采用免疫组化SP法检测并比较了67例不同级别胶质瘤组织和10例正常脑组织中MMP-2和TIMP-2蛋白的表达情况。结果随着肿瘤恶性程度的增加,MMP-2蛋白表达增高而TIMP-2蛋白表达降低。结论MMP-2及TIMP-2对胶质瘤恶性程度的评估有重要的意义。     

Depression and oxidative damage in TNM stage Ⅲ patients with poorly differentiated gastric adenocarcinoma

Objective To investigate the association between psychological stress and oxidative damage in TNM stage Ⅲ patients with poorly differentiated gastric adenecarcinoma (GA). Methods One hundred and six patients with newly diagnosed poorly differentiated GA were assessed using the Hamilton Depression Rating Scale (HAMD), Zung Self-rating Depression Scale (SDS), Zung Self-rating Anxiety Scale (SAS), Symptom Checklist 90 (SCL-90), activities of daily living (ADL) and other multiple-item qnestionnaires. Oxidative-stress-related parameters in serum and the expression of DNA repair genes were monitored during a pretreatment period. Results The patients were divided into depression and nondepression groups (Groups A and B, respectively) based on a HAMD score cutoff of 20. The mean SDS, SAS, SCL-90, ADL and passive coping scores were higher in Group A, whereas social support and quality of life were lower. Serum total antioxidant capacity, eatalase, superoxide dismutuse concentrations and anti-superoxide anion capacity (A-ASC) were significantly decreased in Group A, whereas serum malondialdehyde (MDA) and 8-hydroxy-deoxyguanosine (8-OHdG) levels were significantly increased. Pearson correlation analysis revealed that depression was pesitively correlated with MDA, SAS, SCL-90 and ADL, but negatively correlated with A-ASC. Furthermore, real-time PCR revealed that the expression levels of hOGG1 and APEX1 were increased in Group A. Conclusion Psychological stress might be related to impaired antioxidant system in patients with GA, and it presents the first evidence of the involvement of oxidative DNA damage in the pathogenesis of depression.     

功能状态下无牙颌患者髁状突的应力分布研究

目的构建无牙颌包括下颌骨的颞下颌关节(TMJ)三维有限元模型;探讨戴用全口义齿无牙颌患者在牙尖交错位紧咬牙时颞下颌关节髁状突的应力分布特征。方法以活体人颅为标本,采用螺旋CT断层扫描技术,图像数字化处理等方法在计算机上构建模型,然后在载荷状态下,利用ANSYSV8.0软件进行运算分析。结果建立了无牙颌下颌骨和颞下颌关节三维有限元模型,并在此模型后牙相应位点加载、运算、分析显示:髁突近颈部应力力值明显大于近顶区;前、后斜面由外向内力值逐渐减小;外、内侧由前向后力值逐渐减小,前斜面、外侧上1/2(近髁突顶)区域压应力占主导地位,下1/2(近颈区)区域以拉应力为主,下外侧为主要应力集中区;后斜面及内侧上1/2以拉应力为主,下1/2以压应力为主。结论戴用息止间隙为2mm的全口义齿无牙颌患者,髁状突各区域拉、压应力并存,但每个区域应力分布特征及水平有较大差异;前斜面外侧即关节功能区应力水平明显高于其他区域,符合正常人TMJ功能的特点。     

基于卡尔曼滤波的挖泥船电网谐波监测系统的研究

高次谐波造成挖泥船疏浚生产效率低下、能耗增加、环境污染恶化,为了疏浚船舶的交货质量及正常使用,必须先对挖泥船电网谐波进行监测,再对其进行抑制。本文针对挖泥船电网谐波监测的技术问题,结合挖泥船特定的工况海况,采用卡尔曼滤波(Kalman Filtering,KF)算法,构建挖泥船电网谐波监测系统,具有使用效率高、监测精度高、成本低且适用范围较广等特点。