γ-氨基丁酸在发育期大鼠视皮层长时程增强中的作用

目的　探讨γ 氨基丁酸 (GABA)在发育期大鼠视皮层诱导长时程增强 (LTP)中的作用。方法　应用视皮层脑片电生理技术 ,在大鼠视皮层脑片Ⅳ层刺激而在Ⅱ /Ⅲ层记录场电位 ,在第 2、3、5周龄的大鼠脑片中诱导LTP ,并比较发育过程中LTP的发生率以及GABA在诱导LTP中的作用。结果　在第 5周龄的大鼠脑片中诱导的LTP发生率明显低于第 2及第 3周龄的大鼠。GABAA受体拮抗剂Picrotoxin能够提高第 5周龄的大鼠LTP的发生率 ,但对于第 2及第 3周龄LTP无作用。结论　GABA对于视皮层发育关键期之前LTP的诱导并无易化作用 ;但对于发育关键期后的LTP有抑制作用     

改性乳化沥青稀浆封层车辙修补技术在高速公路的应用

以合徐高速公路改性乳化沥青稀浆封层修补车辙工程为背景,介绍了改性乳化沥青稀浆封层车辙修补技术的特点、工程材料、施工工序、实施效果等,并对经济和社会效益进行了分析。     

公交专用道的运行状态及对社会车道的影响

本文提出了一种分析已有公交专用道运行状态的方法.通过计算公交车道和社会车道上的饱和度,来确定公交车道和社会车道的服务水平,并结合公交专用道上各车型所占比例,分析公交专用道的运行情况及其对社会车道的影响,指出存在的问题和可能的改进措施.     

轻型薄壁墩台施工质量控制

本文论述了轻型薄壁墩台施工中的质量控制.     

硒对培养人肝细胞的毒性作用

原代培养人胚肝细胞，观察外加不同剂量亚硒酸钠对肝细胞生长代谢的影响。结果表明，当培养液中硒的作用浓度增至1．156×10－6mol／L时，肝细胞聚缩、脱落，丙氨酸转氨酶外释增多，白蛋白合成减少，存活率下降。提示过量硒具有明显的肝细胞毒性作用。     

55岁以上自然人群中帕金森病患者认知功能障碍的临床研究

目的　了解 55岁以上自然人群中帕金森病 (Parkinson sdisease ,PD)患者认知功能障碍的发生情况。方法　以流行病学调查资料为基础 ,采用非配对的病例对照研究方法 ,分析 55岁以上自然人群中PD患者认知功能障碍的发生率 ,评估认知功能障碍发生的相对危险性。结果　 55岁以上自然人群中 ,PD组和非帕金森病 (noParkinson sdis ease,NOPD)组认知功能障碍的发生率分别为 2 7.78%、5.55% ;年龄调整的发生率分别为 16.2 0 %、9.87%。与同一自然人群中NOPD组比较 ,PD组发生认知功能障碍的危险性明显增高 ,但主要增加低年龄组 (55～ 74岁 )中老年人发生认知功能障碍的危险性 (OR =8.59,95%CI :3 .13～ 2 3 .80 ) ;而且PD是低年龄中老年人发生认知功能障碍和痴呆的独立危险因素 (OR =6.2 7,95%CI :2 .3 5～ 19.2 7;OR =5.50 ,95%CI :1.52～ 19.94)。年龄调整的MMSE分值的均值PD组明显低于NOPD组 (P <0 .0 0 1)。结论　PD主要增加低年龄 (55～ 74岁 )中老年人认知功能障碍发生的危险性 ,而且PD认知功能障碍是疾病本身所致     

船舶电力信息网络脆弱性分析

船舶电力信息网络的脆弱性分析对确保船舶电网安全、稳定、高效的运行有着重要意义。本文以复杂网络理论为基础,对船舶电力信息网络的脆弱性进行了研究。首先对某一具体的船舶电力信息网络拓扑结构进行抽象,然后在此基础上运用复杂网络理论计算船舶电力信息网络节点脆弱性和链路脆弱性,由此找出整个网络中最脆弱的部分。分析结果表明,该研究可为船舶电力信息网络的优化设计提供依据,并且在在拓扑结构方面着手对信息网络进行了优化提高。     

空心四面块体促淤堤近底水动力特性试验研究*

依据长江口某促淤工程的设计条件及物理模型试验方法对空心四面块体促淤堤近底水动力特性开展研究。结果表明：1）近底紊动强度最大值所在位置、近底水平时均流速最小值所在位置以及近底水平时均流动方向的转变位置基本重合;2）对于某种具体堤型而言,在相同单宽流量条件下,随着相对水深的变化（至少在本文试验范围内）,其紊动强度最大值所在位置比较稳定;3）与抛石加护面块体促淤堤相比,透水性较好的堤身结构近底紊动强度最大值所在位置会更加远离堤轴线,可使局部冲刷坑更加远离堤轴线,对堤身结构稳定有益。     

Design and validation of a slender guideway for Maglev vehicle by simulation and experiment

Normally, Maglev (magnetic levitation) vehicles run on elevated guideways. The elevated guideway must satisfy various load conditions of the vehicle, and has to be designed to ensure ride quality, while ensuring that the levitation stability of the vehicle is not affected by the deflection of the guideway. However, because the elevated guideways of Maglev vehicles in South Korea and other countries fabricated so far have been based on over-conservative design criteria, the size of the structures has increased. Further, from the cost perspective, they are unfavourable when compared with other light rail transits such as monorail, rubber wheel, and steel wheel automatic guided transit. Therefore, a slender guideway that does have an adverse effect on the levitation stability of the vehicle is required through optimisation of design criteria. In this study, to predict the effect of various design parameters of the guideway on the dynamic behaviour of the vehicle, simulations were carried out using a dynamics model similar to the actual vehicle and guideway, and a limiting value of deflection ratio of the slender guideway to ensure levitation control is proposed. A guideway that meets the requirement as per the proposed limit for deflection ratio was designed and fabricated, and through a driving test of the vehicle, the validity of the slender guideway was verified. From the results, it was confirmed that although some increase in airgap and cabin acceleration was observed with the proposed slender guideway when compared with the conventional guideway, there was no notable adverse effect on the levitation stability and ride quality of the vehicle. Therefore, it can be inferred that the results of this study will become the basis for establishing design criteria for slender guideways of Maglev vehicles in future.