硒对培养人肝细胞的毒性作用

原代培养人胚肝细胞，观察外加不同剂量亚硒酸钠对肝细胞生长代谢的影响。结果表明，当培养液中硒的作用浓度增至1．156×10－6mol／L时，肝细胞聚缩、脱落，丙氨酸转氨酶外释增多，白蛋白合成减少，存活率下降。提示过量硒具有明显的肝细胞毒性作用。     

55岁以上自然人群中帕金森病患者认知功能障碍的临床研究

目的　了解 55岁以上自然人群中帕金森病 (Parkinson sdisease ,PD)患者认知功能障碍的发生情况。方法　以流行病学调查资料为基础 ,采用非配对的病例对照研究方法 ,分析 55岁以上自然人群中PD患者认知功能障碍的发生率 ,评估认知功能障碍发生的相对危险性。结果　 55岁以上自然人群中 ,PD组和非帕金森病 (noParkinson sdis ease,NOPD)组认知功能障碍的发生率分别为 2 7.78%、5.55% ;年龄调整的发生率分别为 16.2 0 %、9.87%。与同一自然人群中NOPD组比较 ,PD组发生认知功能障碍的危险性明显增高 ,但主要增加低年龄组 (55～ 74岁 )中老年人发生认知功能障碍的危险性 (OR =8.59,95%CI :3 .13～ 2 3 .80 ) ;而且PD是低年龄中老年人发生认知功能障碍和痴呆的独立危险因素 (OR =6.2 7,95%CI :2 .3 5～ 19.2 7;OR =5.50 ,95%CI :1.52～ 19.94)。年龄调整的MMSE分值的均值PD组明显低于NOPD组 (P <0 .0 0 1)。结论　PD主要增加低年龄 (55～ 74岁 )中老年人认知功能障碍发生的危险性 ,而且PD认知功能障碍是疾病本身所致     

船舶电力信息网络脆弱性分析

船舶电力信息网络的脆弱性分析对确保船舶电网安全、稳定、高效的运行有着重要意义。本文以复杂网络理论为基础,对船舶电力信息网络的脆弱性进行了研究。首先对某一具体的船舶电力信息网络拓扑结构进行抽象,然后在此基础上运用复杂网络理论计算船舶电力信息网络节点脆弱性和链路脆弱性,由此找出整个网络中最脆弱的部分。分析结果表明,该研究可为船舶电力信息网络的优化设计提供依据,并且在在拓扑结构方面着手对信息网络进行了优化提高。     

空心四面块体促淤堤近底水动力特性试验研究*

依据长江口某促淤工程的设计条件及物理模型试验方法对空心四面块体促淤堤近底水动力特性开展研究。结果表明：1）近底紊动强度最大值所在位置、近底水平时均流速最小值所在位置以及近底水平时均流动方向的转变位置基本重合;2）对于某种具体堤型而言,在相同单宽流量条件下,随着相对水深的变化（至少在本文试验范围内）,其紊动强度最大值所在位置比较稳定;3）与抛石加护面块体促淤堤相比,透水性较好的堤身结构近底紊动强度最大值所在位置会更加远离堤轴线,可使局部冲刷坑更加远离堤轴线,对堤身结构稳定有益。     

Design and validation of a slender guideway for Maglev vehicle by simulation and experiment

Normally, Maglev (magnetic levitation) vehicles run on elevated guideways. The elevated guideway must satisfy various load conditions of the vehicle, and has to be designed to ensure ride quality, while ensuring that the levitation stability of the vehicle is not affected by the deflection of the guideway. However, because the elevated guideways of Maglev vehicles in South Korea and other countries fabricated so far have been based on over-conservative design criteria, the size of the structures has increased. Further, from the cost perspective, they are unfavourable when compared with other light rail transits such as monorail, rubber wheel, and steel wheel automatic guided transit. Therefore, a slender guideway that does have an adverse effect on the levitation stability of the vehicle is required through optimisation of design criteria. In this study, to predict the effect of various design parameters of the guideway on the dynamic behaviour of the vehicle, simulations were carried out using a dynamics model similar to the actual vehicle and guideway, and a limiting value of deflection ratio of the slender guideway to ensure levitation control is proposed. A guideway that meets the requirement as per the proposed limit for deflection ratio was designed and fabricated, and through a driving test of the vehicle, the validity of the slender guideway was verified. From the results, it was confirmed that although some increase in airgap and cabin acceleration was observed with the proposed slender guideway when compared with the conventional guideway, there was no notable adverse effect on the levitation stability and ride quality of the vehicle. Therefore, it can be inferred that the results of this study will become the basis for establishing design criteria for slender guideways of Maglev vehicles in future.     

Experimental study on piston- and sloshing- mode moonpool resonances

An experimental study was performed on the piston- and sloshing-mode moonpool resonances of offshore structures. Two different geometries were considered to investigate the flow characteristics in a plain moonpool and a moonpool with a cofferdam. To examine the efficiency of a cofferdam for reducing the flow in a moonpool, three cofferdam geometries were tested. The plain moonpool presented violent flows as a result of the piston- and sloshing-mode resonances. However, the moonpool with the cofferdam introduced violent sloshing waves instead of the ascent and descent of the water column in the piston-mode moonpool resonance. Among three different cofferdam geometries, the model with a right triangle facing to the left on the top of the cofferdam was most effective in reducing the flow in the moonpool when compared with the other models.     

里程延长型电动汽车实现方法探究

为了延长电动汽车的续驶里程,在动力系统中加入了动力辅助单元(APU)。介绍了不同的APU组成和相应的控制策略、延长里程的方式和相应的实验结果并得出结论,证明该方法的有效性与实用性。     

瞬态瑞雷波法在地基固结效果检测中的应用

基于软土固结中剪切波速增值与固结度的关系理论,介绍了将瑞雷波测试技术与室内土工试验成果相结合,检测分析软土地基固结效果的方法.将该检测方法应用于路基工程中,并与原位孔隙水压力监测成果对比分析,说明该方法是可靠的.     

汶川地震后对我国结构工程抗震的几点思考

通过前两位作者前后两次赴汶川地震灾区进行考察调研,获取了震害的第一手资料。首先阐述了汶川地震的特点,分析了结构工程特别是桥梁工程震害产生的原因;研究了桥型与抗震性能的关系,提出在不同场地和不同条件下应采用不同的桥型、高烈度地震区的适宜桥跨结构型式应进行深入研究;探讨了桥梁结构的抗震设防标准问题,建议对重要性公路桥梁,采用中震不坏的设计原则;讨论了概念设计与抗震构造措施对桥梁抗震的重要性;提出应重视减隔震耗能技术在桥梁工程中的应用;根据国外的经验,建议对桥梁结构的抗震评价与加固技术进行深入的探讨和研究;探讨了我国在灾害的应急决策机制、防灾减灾政策和技术研究等方面存在的问题;最后,针对目前我国结构抗震中存在的问题,提出了相应的建议。     

BSG混合动力轿车动力系统参数设计及试验研究

介绍了BSG混合动力轿车动力系统的结构及工作原理,对发动机、BSG电机、蓄电池以及传动系传动比进行了参数设计,并对BSG电机不参与工作和参与工作两种状态下轿车的动力性、燃油经济性和排放性能进行了对比试验.试验结果表明,BSG电机参与工作时BSG混合动力轿车的动力性、燃油经济性和排放性能均有显著改善.