T_H1 AND T_H2 CELL ANTIGEN RECEPTORS IN EXPERIMENTAL LEISHMANIASIS

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Impact of information technology on public transport fares data

The work described was undertaken as part of the CASSIOPE project in the EC DRIVE programme. A range of fare collection procedures in public transport is described, and the importance of these for data collection by operators is stressed. It is suggested that such data management could be standardized and to this end four case studies were carried out in different European cities. Data models were built for each city, and these models are merged into a preliminary version of a generalized model. The need and uses for such a fare collection data model is explained.     

Mathematical Modelling of Vibrations and Loading of Railway Tanks Taking into Account the Liquid Cargo Mobility

Dynamics and loading of railway tank cars transporting liquid cargo are investigated. The approach based on the mechanical-pendulum analogy for the liquid cargo mobility simulation is proposed. Hydrodynamic parameters of the mechanical analogy are determined using the solution of the boundary-value problem for the liquid cargo vibrations in a cavity with the tank boiler shape. The fitting of the developed mathematical models is proved by comparison of calculated results and test data. Vibration characteristics and loading of tank-cars under their shunt collisions and motion along straight and curved track in trains are evaluated. It is shown that as a rule the liquid cargo mobility has an essential influence on tank dynamic properties.     

The dynamics of traffic assignment and traffic control: A theoretical study

The paper considers traffic assignment, with traffic controls, in an increasingly dynamic way. First, a natural way of introducing the responsive policy, P_o, into steady state traffic assignment is presented. Then it is shown that natural stability results follow within a dynamical version of this static equilibrium model (still with a constant demand). We are able to obtain similar stability results when queues are explicitly allowed for, provided demand is constant. Finally we allow demand to vary with time; we consider the dynamic assignment problem with signal-settings now fixed. Here we assume that vehicles are very short and that deterministic queueing theory applies, and show that the time-dependent queueing delay at the bottleneck at the end of a link is a monotone function of the time-dependent input profile to the bottleneck. We have been unable to obtain results when dynamic demand and responsive signal control are combined.     

Coupled transport-reaction pathways and distribution patterns between siliciclastic-carbonate sediments at the Ria de Vigo

This paper examines the linkages between the space-distribution of grain sizes and the relative percentage of the amount of mineral species that result from the mixing process of siliciclastic and carbonate sediments at the Ria de Vigo (NW of Spain).The space-distribution of minerals was initially determined, starting from a detailed mineralogical study based on XRD-Rietveld analysis of the superficial sediments. Correlations between the maps obtained for grain sizes, average fractions of either siliciclastic or carbonates, as well as for individual-minerals, were further stabilised. From this analysis, spatially organized patterns were found between carbonates and several minerals involved in the siliciclastic fraction. In particular, a coupled behaviour is observed between plagioclases and carbonates, in terms of their relative percentage amounts and the grain size distribution.In order to explain these results a conceptual model is proposed, based on the interplay between chemical processes at the seawater–sediment interface and hydrodynamical factors. This model suggests the existence of chemical control mechanisms that, by selective processes of dissolution-crystallization, constrain the mixed environment's long-term evolution, inducing the formation of self-organized sedimentary patterns.     

Effect of fatigue strain range on properties of high-strength structural steel

Ship hulls are built with stiffened steel plates and experience continuous fatigue load cycles when in service. Mechanical properties of the steel are expected to change due to the application of these cyclic loads. Therefore, the mechanical properties of the material at various levels of fatigue damage need to be understood. This paper presents two test series that were conducted to determine the effect of two different strain ranges (2000 and 3000 micro strains) of fatigue cycles on the mechanical properties of high-strength structural steel. The test results indicate that the cycle-dependent behaviours of the material can cause a slight increase or a significant decrease in the yield strength when compared to its virgin state. However, the ductility of the steel does not change much as the strain cycle increases.     

Effects of information in road transport networks with recurrent congestion

This paper aims to gain more insight into the implications of information provision to drivers on the performance of road transport networks with recurrent congestion. For this purpose, a simulation program consisting of three components has been written. The first component is the traffic simulation model, the second component is the information provision mechanism, and the third component monitors the behavioural decision-making process of the drivers, which is modelled using a utility-based satisficing principle. Three types of information provision mechanisms will be considered: information based upon own-experience, after-trip information and real-time en route information. The findings in this paper, obtained in a hypothetical context, underline the important relationship betweenoverreaction, thelevel of market penetration and thequality of the information. High quality information allows a high level of market penetration, while low quality information, even when provided at low levels of market penetration, induces overreaction. Furthermore, real-time en route information is in particular beneficial during the process leading to a steady state; it reduces the variance in travel time considerably. The paper concludes with a discussion on the market potential of motorist information systems when commercially marketed.     

Wave impact on a horizontal elastic plate

The objective is to find slamming-induced local stresses in the steel or aluminum wetdeck of a multihull vessel. This is studied theoretically by representing the wetdeck as a beam model and accounting for dynamic hydroelastic effects. Two numerical methods are used, one being a simplified asymptotic solution. Satisfactory agreement between the two methods is reported. Experimental drop tests of horizontal elastic plates of steel and aluminum are also reported, and the results from the experiments agree well with the numerical computations. This study reveals, both numerically and experimentally, that slamming-induced local stresses are strongly influenced by dynamic hydroelastic effects. The maximum bending stresses are insensitive to where waves hit, the curvature of the waves, and maximum pressures. Measured maximum pressures are very sensitive to external conditions, and cannot be used as a measure of maximum local bending stresses. A simple procedure for local design stresses due to wetdeck slamming is outlined.     

The coastal edge of the Northeast Water polynya in spring 1993

Multidisciplinary, marine ecological observations were conducted at the shallow water edge of the Northeast Water in June, 1993. Although variable in size and shape, a small polynya was constantly present at Eskimonaes, at the fast-ice edge of Ingolfsfjord. A shallow stratified layer developed at the water sufface at negative water and air temperatures—an effect of sea ice melting in cold water early in the season. Nutrients were recorded in considerable quantities, although by mid July NO₃ had become depleted. The chlorophyll and phytoplankton maxima at 8–12 m depth had peak values of 2 mg chl a m⁻³, typical for Arctic algal blooms. The phytoplankton included over 90 species and was dominated by the Fragillariopsis group. Zooplankton was poor in biomass and density, but over 23 taxa were found, with the copepods Oithona similis and Pseudocalanus acuspes being numerically dominant. Sedimentation was approximately 0.2 g dry weight m⁻² d⁻¹ and suspended matter concentrations ranged from 4 to 19 mg l⁻¹. The benthos was represented by hard bottom forms only, with a surprisingly dense cover of macrophytes. Juvenile sea urchins (Strongylocentrotus droebachiensis), brittle stars (Ophiocten sericeum) and amphipods were dominant. Higher trophic levels were represented by benthic feeders, such as eiders and walruses. The area observed was more similar to high Arctic fjord ecosystems than to the offshore central Northeast Water polynya.     

Eddies around Madagascar — The retroflection re-considered

The Agulhas Current with its retroflection and attendant eddy-shedding is the cause of some of the greatest mesoscale variability in the ocean. This paper considers the area to the south and east of Madagascar, which provides some of the source waters of the Agulhas Current, and examines the propagating sea surface height signals in altimetry and output from a numerical model, OCCAM. Both show bands of variability along the axis of the East Madagascar Current (EMC) and along a zonal band near 25°S. Sequences of images plus associated temperature data suggest that a number of westward-propagating eddies are present in this zonal band. The paper then focuses on the region to the south of the island, where ocean colour and infra-red imagery are evocative of an East Madagascar Retroflection. The synthesis of data analysed in this paper, however, shows that remotely observed features in this area can be explained by anticyclonic eddies moving westward through the region, and this explanation is consistent with numerical model output and the trajectories of drifting buoys.