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841.
以人胃癌细胞株为实验对象,采用MTT显色法在体外观察了金属类抗癌药物氯化镓与人α-干扰素的协同抑制作用。结果显示:单独加入α-干扰素无明显抑制作用,而与氯化镓同时加入则有明显的抑制作用,尤其是当先用α-干扰素或氯化镓孵育72h后,再交换加药其协同抑制作用更大。提示:在应用氯化镓治疗胃癌病人时可同时合用干扰素治疗,或先用α-干扰素一段时间再用氯化镓治疗其疗效可能更好。  相似文献   
842.
Fundamental Issues in Suspension Design for Heavy Road Vehicles   总被引:8,自引:0,他引:8  
Heavy road vehicles play an important role in the economy of many countries by providing an efficient means of transporting freight. Such vehicles can also have a significant impact on safety, the infrastructure and the environment. The design of the suspension affects the performance of the vehicle in terms of ride, infrastructure damage, suspension working space, energy consumption, rollover stability, yaw stability, braking and traction. The published literature on suspension design for heavy road vehicles is reviewed. It is found that extensive knowledge exists, but that there are areas where improved understanding is needed. Areas identified as fundamental issues requiring attention include ride discomfort criteria, secondary suspensions, and controllable suspensions. Two issues in particular are examined in detail: suspension tuning and suspension configuration. In the tuning of suspension parameter values for vibration performance, numerical optimisation techniques have been used extensively, but generic tuning strategies have not been widely developed. Modal analysis is proposed as a technique for gaining the insight into vehicle vibration behaviour necessary to enable tuning strategies to be devised. As an example, the technique is applied to the pitch-plane vibration of a tractor-semitrailer. In analyses of new suspension configurations or concepts, comparison with alternative concepts is not always made. Lack of such comparisons makes the selection of an optimum concept difficult. Analysis of alternative concepts using simple mathematical models, and comparison of their performance using common criteria, is advocated for enabling informed selection of an optimum. An example involving two alternative roll control systems is used to demonstrate the issue.  相似文献   
843.
阐述了机车橡胶堆旁承横向刚度计算的基本原理,提出了一种新的计算方法,并经过了实验验证,另外还分析了影响计算准确性的主要因素。  相似文献   
844.
1957~1987年我院共收治恶性滋养细胞肿瘤342例,发生子宫穿孔26例。其中绒毛膜癌147例,穿孔者16例,占10.9%;侵蚀性葡萄胎195例,穿孔10例,占5.1%。其主要症状为阴道流血、阵发性腹痛或腹部剧痛,下腹部有压痛、反跳痛及移动性浊音。21例行急诊手术,术后3天开始化疗。死亡3例,均系绒癌Ⅳ期患者。23例经手术加化疗后治愈。  相似文献   
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846.
Urban transportation is identified as a functional element in the broader context of urban facilities and services. From this point of view, the relative merits of separate information systems for transportation planning and general urban planning, as contrasted to unified systems for all urban management functions, are discussed. The overriding need to make the most effective use of urban resources argues strongly for the unification of urban information systems to the greatest possible extent consistent with the special data requirements of various functional programs. The need to identify and correlate data items for very small areal units and to keep current records of the constantly shifting patterns of social and economic activities in urban areas present difficult, but not insurmountable technical problems. However, the most serious barrier to the development and implementation of comprehensive urban information systems is concluded to be institutional, rather than technical, in nature.  相似文献   
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850.
The absence of formal career-development programmes and the apparent low priority given to the development of human resources in the ports of developing countries has led to a severe shortage of suitably qualified and experienced managers. At the centre of this problem lies the formidable barriers to the establishment of a local training capability to meet the diverse and often specialized needs of this industry. This paper examines the nature and scale of the management-training requirements of the ports of developing countries. Further, it briefly describes the background to UNCTAD's role in the field of management training and outlines the objectives of its training strategy for the 1980s. An important component of this strategy is the 'Improving port performance project which is designed to prepare structured learning materials using audio-visual techniques and is proposed as one solution to establishing a local training capability in developing countries.  相似文献   
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