有限元分析法在OSAHS疾病个性化治疗方案中的可行性研究

目的通过定量描述呼吸气流流场分布情况,探索有限元分析法在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)疾病诊断、治疗及术后评估中的可行性。方法对1例重症OSAHS患者进行睡眠状态CT检查,将数据以Dicom格式保存后导入Mimics软件进行三维重建,Geomagic软件进行曲面拟合,Pro/e中完成对呼吸道进出口的修改,使用Fluent软件进行仿真计算。结果 1对OSAHS患者上呼吸道数值模拟结果可以看出,手术前流场内压力和速度变化最明显的位置是鼻咽腔,主要位于软腭平面,流场速度为22.91m/s,压力梯度变化最明显处为-186.32Pa。2此患者在计算机模型中模拟咽腔扩宽,主要是软腭平面。在临床中实施的手术方案为悬雍垂腭咽成型术、双侧扁桃体切除术联合双下鼻甲骨折外移术。模拟术后最大气流速度为19.39m/s,压力梯度变化最明显处为-150.9Pa,其发生在会厌上缘位置。结论有限元分析能够初步量化OSAHS患者呼吸道阻塞位点,为患者手术方式的选择及术后效果评估提供比较参数,在临床中具有可行性。     

Twist和VEGF在上皮性卵巢癌中的表达

目的探讨Twist及VEGF在卵巢癌发生发展中的作用及其与临床病理特征的关系。方法采用免疫组化SP法检测Twist及VEGF蛋白在80例上皮性卵巢癌组织中的表达情况,并选取10例正常卵巢组织作为对照。结果在80例上皮性卵巢癌组织中,Twist及VEGF蛋白均表达于细胞质中,其阳性表达率分别是85%(68/80)、86.25%(69/80),明显高于正常卵巢组织,差异均有统计学意义(P<0.01)。Twist和VEGF表达与上皮性卵巢癌临床分期、病理分级、淋巴结转移相关(P<0.01),与年龄、病理类型无关(P>0.05)。在上皮性卵巢癌中,Twist与VEGF蛋白的表达呈正相关(r=0.646,P<0.01)。结论 Twist及VEGF在上皮性卵巢癌的发生、发展和侵袭中有重要作用。     

完整街道理念下的城市道路横断面规划

完整街道设计理念注重维护所有道路活动者的空间权利,重视人行道、自行车道、公交专用车道设计以及对路侧步行空间的协同考虑,有利于纠正国内城市道路设计偏重小汽车交通的误区。首先,突破国内现行道路红线管理范畴,将道路空间规划对象扩展至建筑前区。然后,在分析国外完整街道设计内容的基础上,探讨国内完整道路横断面规划控制原则体系。最后,以天津市道路横断面设计实践为例,分析完整街道实施进展与现存问题,以期推动完整街道理念在国内的推广与落实。     

泡沫温拌沥青混合料压实温度室内研究

为确定泡沫温拌沥青混合料的室内压实温度,选择泡沫沥青Sup20混合料与道路石油沥青Sup20混合料进行室内的旋转压实试验,对比不同温度下成型试件的体积指标,确定泡沫温拌的压实温度,并且选择泡沫沥青的粘温曲线以及路用性能进行验证.结果表明:粘温曲线与体积指标确定的压实温度一致,泡沫沥青混合料的路用性能均满足规范要求,所以泡沫温拌沥青Sup20混合料的室内压实温度为130℃.     

利用AGM求解粘弹性地基刚性梁的非线性控制微分方程（英文）

In the present paper a vibrational differential equation governing on a rigid beam on viscoelastic foundation has been investigated. The nonlinear differential equation governing on this vibrating system is solved by a simple and innovative approach, which has been called Akbari-Ganji’s method(AGM). AGM is a very suitable computational process and is usable for solving various nonlinear differential equations. Moreover, using AGM which solving a set of algebraic equations, complicated nonlinear equations can easily be solved without any mathematical operations.Also, the damping ratio and energy lost per cycle for three cycles have been investigated. Furthermore, comparisons have been made between the obtained results by numerical method(Runk45) and AGM. Results showed the high accuracy of AGM. The results also showed that by increasing the amount of initial amplitude of vibration(A), the value of damping ratio will be increased, and the energy lost per cycle decreases by increasing the number of cycle. It is concluded that AGM is a reliable and precise approach for solving differential equations. On the other hand, it is better to say that AGM is able to solve linear and nonlinear differential equations directly in most of the situations. This means that the final solution can be obtained without any dimensionless procedure.Therefore, AGM can be considered as a significant progress in nonlinear sciences.     

三峡水库蓄水后宜都水道演变及航道变化

依据蓄水前后原型观测资料,分析了三峡工程蓄水前后宜都河段——三峡枢纽下游的低水分汊河段的河势和河床冲淤变化情况及其对航道的影响,并对该河段的演变趋势进行了预测。结果表明,来沙量减少使宜都水道冲刷,沙泓上浅区冲刷下切,而下浅区以冲滩为主,石泓深泓冲刷下降,南阳碛冲刷缩小,分流格局有发生变化的趋势。沙泓上浅区航道条件改善,但下浅区航道展宽左摆,发展下去不利于航道维护。     

武桥水道水动力特性与潜洲演变研究

武桥水道枯水期碍航与汉阳边滩的发育程度直接相关,而汉阳边滩的发育又与潜洲演变紧密相连.采用定床模型试验结合原观资料分析的方法,分析武桥水道河段水流运动特性、潜洲年内年际的演变规律以及两者之间的内在联系.结果表明:武汉河段周界条件和水流运动规律使得本河段汛期水流动力轴线顺直,潜洲至大桥间水流动力轴线居中靠左:而枯水期水流动力轴线弯曲,在潜洲头部和尾部形成斜向水流,水流动力轴线在潜洲尾部以下由左侧过渡到右侧.不同流量水流动力特性的变化直接决定了年内潜洲的冲淤变化规律:洪水期潜洲淤积,头部上延;尾部下挫;而枯水期冲刷,头部后退,尾部上提.     

Discourse of maritime forms (Check lists)

Check lists represent a very important tool within the International Safety Management Code, aimed at the regular and thorough assessment of the safety on board ships along with the operation of their parent companies. There seems to be only a few academic articles studying the communicative and rhetorical aspects of these maritime forms explaining why they are written in the way they are, especially in the light of their users who constitute a specific discourse community. The structure of a sample of representative lists is presented, as these check lists do not differ from the forms used by other European shipping companies. After interviews with the seafarers (deck and engine officers) to whom the check lists were administered, the conclusion was reached that they prefer short and unambiguous forms. In addition, a correlation about the language competence of the crew members on board ship was found: the simpler the discourse of the check list, the lower the responsibility of the crew member on board. Further, investigation into these complex language patterns focuses on the practical benefits.     

Examination of relationships between urban form,household activities,and time allocation in the Atlanta Metropolitan Region

A substantial body of research is focused on understanding the relationships between socio-demographics, land-use characteristics, and mode specific attributes on travel mode choice and time-use patterns. Residential and commercial densities, inter-mixing of land uses, and route directness in conjunction with transportation performance characteristics interact to influence accessibility to destinations as well as time spent traveling and engaging in activities. This study uniquely examines the activity durations undertaken for out-of-home subsistence; maintenance, and discretionary activities. Also examined are total tour durations (summing all activity categories within a tour). Cross-sectional activities are obtained from household activity travel survey data from the Atlanta Metropolitan Region. Time durations allocated to weekdays and weekends are compared. The censoring and endogeneity between activity categories and within individuals are captured using multiple equations Tobit models.The analysis and modeling reveal that land-use characteristics such as net residential density and the number of commercial parcels within a kilometer of a residence are associated with differences in weekday and weekend time-use allocations. Household type and structure are significant predictors across the three activity categories, but not for overall travel times. Tour characteristics such as time-of-day and primary travel mode of the tours also affect traveler’s out-of-home activity-tour time-use patterns.     

和谐HX_D1型大功率交流电力机车空气制动系统

介绍HXD1型大功率交流电力机车制动系统的构成,并对其风源系统和制动控制系统的工作原理及主要部件进行了详细阐述。