REGULATION OF PRODUCTION OF PARATHYROID HORMONE－RELATED PEPTIDE （PTHrP） AND EXPRESSION OF ITS mRNA IN A HUMANLIVER－DERIVED CE

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A traffic flow simulator for short‐term travel time forecasting

This paper presents an off‐line forecasting system for short‐term travel time forecasting. These forecasts are based on the historical traffic count data provided by detectors installed on Annual Traffic Census (ATC) stations in Hong Kong. A traffic flow simulator (TFS) is developed for short‐term travel time forecasting (in terms of offline forecasting), in which the variation of perceived travel time error and the fluctuations of origin‐destination (O‐D) demand are considered explicitly. On the basis of prior O‐D demand and partial updated detector data, the TFS can estimate the link travel times and flows for the whole network together with their variances and covariances. The short‐term travel time forecasting by O‐D pair can also be assessed and the O‐D matrix can be updated simultaneously. The application of the proposed off‐line forecasting system is illustrated by a numerical example in Hong Kong.     

The influence of the Agulhas Current on the adjacent coastal ocean: possible impacts of climate change

The dynamics of the coastal ocean along the southeastern coast of Africa is dominated by a strong and intense western boundary current, the Agulhas Current. With a near-uniform, narrow continental shelf and a steep shelf slope that stabilizes this current, the trajectory of the Agulhas exhibits great stability. The only substantial perturbation occurs with the irregular passage of a Natal Pulse, a soliton meander. The initiation of this meander at the Natal Bight is due to a barotropic instability when the intensity of the landward border of the current exceeds a certain threshold value. This may come about with natural fluctuations in the current or with the adsorption of deep-sea eddies onto the current. Under a climate change scenario of altered wind stress curl over the South Indian Ocean it is conceivable that the threshold for the triggering of a Natal Pulse will occur more frequently. This will lead to a situation where the current axis on average lies further offshore. The possible consequences of such a situation on the rainfall of the coast, on the ecology of estuaries and the coastal ocean, and on the socio-economics of the region is discussed.     

Active Roll Control for Passenger Cars

The development of a mathematical model of a limited bandwidth hydro-pneumatic suspension that is incorporated into a vehicle handling model is described. The combined model is used to evaluate a suitable control strategy for eliminating body roll during a cornering manoeuvre. The philosophy behind the roll control strategy has been to use feedback measurements of the body motions which do not compromise the ride control. A study of the influence of the position of the body motion feedback transducer on the effectiveness of the system to reduce the body roll is presented. Non-linear modelling of the suspension components for a 0.8g cornering manoeuvre has revealed performance limitations. Conclusions are drawn as to the effectiveness of the control scheme.     

Equilibria of bilateral taxi–customer searching and meeting on networks

This paper proposes an equilibrium model to characterize the bilateral searching and meeting between customers and taxis on road networks. A taxi driver searches or waits for a customer by considering both the expected searching or waiting time cost and ride revenue, and a customer seeks a taxi ride to minimize full trip price. We suppose that the bilateral taxi–customer searching and meeting occurs anywhere in residential and commercial zones or at prescribed taxi stands, such as an airport or a railway station. We propose a meeting function to spell out the search and meeting frictions that arise endogenously as a result of the distinct spatial feature of the area and the taxi–customer moving decisions. With the proposed meeting function and the assumptions underlying taxi–customer search behaviors, the stationary competitive equilibrium achieved at fixed fare prices is determined when the demand of the customers matches the supply of taxis or there is market clearing at the prevailing searching and waiting times in every meeting location. We establish the existence of such an equilibrium by virtue of Brouwer’s fixed-point theorem and demonstrate its principal operational characteristics with a numerical example.     

Red-light cameras at intersections: Estimating preferences using a stated choice model

Red-light cameras placed at intersections have the potential to increase safety, but they are often viewed as an invasion of privacy. Preferences for these cameras were explored using a stated choice model that presents key attributes of camera placements. Stated choice models involve careful experimental design, akin to experimental control in laboratory settings. A variety of design approaches were used, settling on a composition of the choice sets people face in the survey. To illustrate the approach, an internet survey was used with a convenience sample containing a high percentage of college students. The results show that while not the case independently, as the number of cameras and fines for violators are simultaneously increased, the preferences for one particular red light cameras program are likely to improve.     

Route choice of cyclists in Zurich

This paper presents the first route choice model for bicyclists estimated from a large sample of GPS observations and overcomes the limitations inherent in the generally employed stated preference approach. It employs an improved mode detection algorithm for GPS post-processing to determine trips made by bicycle, which are map matched to an enriched street network. The alternatives are generated as a random sample from an exhaustive, but constrained search. Accounting for the similarity between the alternatives with the path-size factor the MNL estimates show that the elasticity with regards to trip length is nearly four times larger than that with respect to the share of bike paths. The elasticity with respect to the product of length and maximum gradient of the route is small. No other variable describing the routes had an impact. The heterogeneity of the cyclists is captured through interaction terms formulated on their average behaviour.