In-vitro and in-vivo electrical characteristics of a penetrating microelectrode array for optic nerve electrical stimulation

The Chinese C-Sight team aims to restore vision to blind patients by means of stimulating the optic nerve with a penetrating microelectrode array. A biocompatible, implantable microwire array was developed having four platinum-iridium shafts, each 100 μm in diameter. This penetrating microwire array is described in this paper, including its fabrication techniques and its in-vitro electrical characteristics. Every set of four shafts was spaced 0.4mm from center to center, comprising two short shafts that were 0.3mm long and two that were 0.9mm long. This design was intended to stimulate ganglion cell axons at different depths within the optic nerve. In-vitro electrochemical impedance testing results showed that the impedance at 1 kHz ranged from 8 to 10 kΩ at room temperature. The voltage responses of the arrays to current pulse stimulation indicated a charge-injection capacity of 210 μC/cm². Finally, in-vivo acute animal experiments showed that the amplitude of the electrically evoked potentials (EEPs) measured in primary visual cortex could be as large as 100 μV upon direct stimulation of the optic nerve.     

公路飞机跑道净空要求分析探讨

为了保证飞行安全,基于我军现有作战飞机的使用条件,分析现行公路飞机跑道净空规定存在的问题,从公路飞机跑道净空影响因素、净空要求出发,参照现行有关标准、规范的净空规定,提出了公路飞机跑道净空区组成和要求,进行了指标来源分析,为公路飞机跑道的建设和净空保护提供了技术依据.