海事行政处罚过程中适用简易程序的必要性分析

海事行政处罚是海事行政管理部门法定职责中的重要组成部分,行政处罚法是其保障执法合法性以及合理性的重要依据.2021年新修订的《行政处罚法》对简易程序进行了修改,在海事行政处罚中适用简易程序对于提高案件办结效率、提升执法满意度有重大意义.通过分析简易程序的特点、适用必要性以及目前在海事行政执法中适用存在的困难,提出可在海...     

高速公路零征地加筋拓宽路堤监测分析

为掌握高速公路零征地加筋拓宽路堤施工和运营过程中特性,对其进行了系统的监测和分析。监测为期2年,监测项目包括路基侧向水平位移、土压力、孔隙水压力等。监测表明,各监测指标的变化主要发生在拓宽路堤施工期与完工后3个月内,其后各监测指标变化较小;采用粉喷桩处理软土地基时,粉喷桩为刚性桩,桩与桩间土不是协调变形,以粉喷桩为主承受上部荷载。分析结果表明:设计方案和施工方案较好,能保证拓宽工程的变形和稳定性要求;零征地加筋拓宽路堤具有较高的稳定性和安全性;为避免拓宽路基的不均匀沉降导致路面开裂,对于拓宽路基宜采用先进行一段时间的堆载预压,然后再修筑路面的施工方法。     

公交线路对双车道交通流的影响分析

采用元胞自动机模型对具有公交线路的双车道混合交通系统进行建模和模拟分析. 通过绘制系统的基本图和右车道上车辆占有率分析了公交线路对双车道车流演化特性以及运行效率的影响,并针对港湾式和非港湾式两种停靠方式的优劣进行比较. 研究结果显示,系统中存在四个车流演化特性不同的密度区域;系统中公交车数量增多会导致最大流量降低;港湾式停靠站的公交线路系统对车流的影响小,系统流量大,优于非港湾式停靠站的公交线路系统.     

CRTSⅡ型板式无砟轨道轨道板力学性能试验研究

通过七块CRTSⅡ型无砟轨道轨道板的静载和疲劳试验,发现轨道板在开裂前基本处于弹性状态,其控制截面实测应变值与实体单元、板单元有限元模型的理论计算结果较为吻合,而与初等梁理论的计算结果在轨下截面偏差较大;轨道板的静力强度均满足规范要求,但疲劳强度需进一步加强,施工过程中应加强对预应力工序的控制。     

超大跨径钢斜拉桥的温度荷载调研与温度效应分析

以苏通大桥为背景,调研各国规范对斜拉桥温度作用的相关规定,进而研究超大跨径钢斜拉桥的温度静力响应。研究将斜拉桥的温度作用分为体系温差、索梁（塔）温差、主梁温度梯度、主塔温度梯度四个方面分别讨论,利用考虑几何非线性影响的有限元软件ANSYS计算分析斜拉桥的温度效应及各构件对温度的敏感性。分析结果可以为今后同类桥梁的设计或计算提供参考和依据。     

基于MC9S12HZ256的汽车仪表步进电机控制

介绍了MC9S12HZ256微控制器的电机控制模块（MC）和失步检测模块（SSD）,提出了使用该模块控制汽车仪表步进电机的方法,给出了控制软件的流程图。通过所研制的汽车组合仪表对步进电机驱动控制和归零控制进行了调试,结果表明,步进电机运行准确、性能可靠。     

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道路拥挤定价收入再分配研究是道路拥挤定价发展中迫切需要解决的实践难题和理论研究的前沿性课题. 本文综述了国内外道路拥挤定价收入再分配相关的社会福利、公众支持和收入再分配方式等方面理论研究发展历程和最新进展,并给出了我国城市道路交通推行该政策的建议. 国内外研究和实践表明,需要在优先考虑提升交通运输效率的基础上,从解决道路拥挤定价政策所产生的福利分配不公平问题和提高公共认知与支持角度出发,制定和实施合理可行的道路拥挤定价收入再分配策略和配套措施,才有助于增强道路拥挤定价政策实施的可行性和有效性,从而更好地改善道路拥挤状况,提高道路运输效率.     

Effects of Panax notoginseng saponins on hydrogen peroxide-induced apoptosis in cultured rabbit bone marrow stromal cells

Objective To investigate the effects of Panax notoginseng saponins (PNS) on hydrogen peroxide (H2O2)-induced apoptosis in cultured rabbit bone marrow stromal cells (BMSCs). Methods BMSCs from 3-month-old New Zealand rabbits were isolated and cultured by the density gradient centrifugation combined with adherent method. The cultured BMSCs were divided into three groups: normal control, H2O2 treatment (100μmol/L), and PNS pretreatment (0.1g/L). Intracellular reactive oxygen species (ROS) levels as the index of oxidative stress were measured by using 2'7'-dichlorodihydrofluorescein diacetate. Flow cytometry was used to observe the apoptosis of BMSCs by staining with annexinV-FITC/PI. The protein expression of Bax in BMSCs was analyzed by Western blotting. Activity of caspase-3 enzyme was measured by spectrofluorometry. Results Pretreatment with PNS significantly decreased intracellular ROS level induced by H2O2 (P<0.01). PNS markedly attenuated H2O2-induced apoptosis rate from 38.68% to 19.24%(P<0.01). PNS reversed H2O2-induced augmentation of Bax expression. Furthermore, PNS markedly reduced the altered in activity of caspase-3 enzyme induced by H2O2(P<0.01). Conclusion PNS has a protective effect on hydrogen peroxide-induced apoptosis in cultured rabbit BMSCs by scavenging ROS and decreasing Bax expression and caspase-3 activity.     

Effects of erigeron breviscapus （Vant.） Hand-Mazz pretreatment on pathology and oxyradical level following spinal cord ischemia-reperfusion injury in rabbits

Objective To investigate the effects of erigeron breviscapus (Vant.) Hand-Mazz (erigeron breviscapus) pretreatment on pathology and oxyradical level in the spinal cord after ischemia-reperfusion (I/R) injury in rabbits. Methods A total of 40 New Zealand white rabbits were randomly divided into three groups: sham-operation group with 10 rabbits treated with only abdominal aorta exposure without occlusion, control group with 15 rabbits that underwent ischemia for 50 minutes and treated with matched saline, and experimental group with 15 rabbits that underwent ischemia for 50 minutes and treated with erigeron breviscapus (9mg/kg) injection before ischemia. Malondialdehyde (MDA) level and superoxide dismutase (SOD) activity in the spinal cord were examined at 6 and 24 hours after I/R, respectively. The morphological changes and the number of the spinal cord anterior horn motor neurons were observed and counted under the light microscope and electron microscope, respectively. Results The level of MDA was markedly decreased and SOD activity was increased in the experimental group compared with those in the control group (P<0.01). Compared with that in the control group, the number of motor neurons in the experimental group significantly increased at 24h after I/R (P<0.01) and the morphous of the motor neurons improved. Conclusion Erigeron breviscapus can reduce oxyradical production and the apoptosis of nerve cells, and protect nerve tissue structure and function after spinal cord I/R.     

高职院校思想政治理论课与校园文化有机结合的路径探索

文章认为思想政治理论课与校园文化建设具有目标的一致性、内容的交叉性和形式的互补性,完全应当而且可以实现二者的有机结合,并从领导体制、有效载体、组织形式、师资保障四个方面提出了如何实现这种有机结合的切实可行的途径。