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51.
Urban arterial performance evaluation has been broadly studied, with the major focus on average travel time estimation. However, in view of the stochastic nature of interrupted flow, the ability to capture the characteristics of travel time variability has become a critical step in determining arterial level of service (LOS). This article first presents a stochastic approach that integrates classic cumulative curves and probability theories in order to investigate delay variability at signalized intersections, as a dominant part of the link travel time variability. This serves as a basis for arterial travel time estimation, which can be obtained through a convolution of individual link travel time distributions. The proposed approach is then applied in the estimation of travel time along one arterial in Shanghai, China, with abundant automatic vehicle identification (AVI) data sources. The travel time variability is evaluated thoroughly at 30-min intervals, with promising results achieved in comparison to the field measurements. In addition, the estimated travel time distributions are utilized to illustrate the probability of multiple LOS ranges, namely, reliability LOS. The results provide insights into how we might achieve a more reliable and informative understanding of arterial performance. 相似文献
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目的建立兔眼房水中环孢霉素A缓释微球的高效液相测定方法,考察在不同给药剂量下兔眼房水中的药物代谢特性,为该药预防后发性白内障提供理论依据。方法兔眼行晶体囊外摘除,左眼前房及囊袋内注射环孢素微球,右眼给予空白微球作对照,采用高效液相色谱法监测给药后4周内兔眼房水中环孢霉素A的浓度。色谱柱为反相C18硅胶柱,柱温为60℃,流动相为乙腈-水(67∶33),检测波长210nm。结果兔眼房水中环孢霉素A的浓度在0.13-1.25mg/L范围内呈良好线性关系(r=0.9951),最低检测浓度0.13mg/L,回收率95.91%,日间和日内精密度均小于5.0%。缓释微球的释药速率适中,兔眼前房给药后可在2周内维持较高浓度,高低两种给药剂量下,环孢霉素A的吸收半衰期(t1/2Ka)和血浆清除速率(CL)经检验无统计学差异,药时曲线下面积(AUC)和峰浓度(Cmax)与剂量之间线性相关。结论环孢素A缓释微球在兔眼内有较高的生物利用度,实验期内可达到抑制后发性白内障的有效浓度。 相似文献
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阐述了地质超前预报的必要性和重要性,介绍了PUSLE-EKKO系列地质雷达系统构成及探测原理,举例说明PUSLE-EKKO地质雷达在公路隧道建设中的应用。 相似文献
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In order to study the diffusion law of grouting slurry in the water-rich sand layer under flowing water conditions, a grouting test model consisting of a main test system, a grouting system, and a measurement system was developed. And for detecting the diffusion scope of the grouts, a new resistivity method was proposed. It is found that the relationship between grouting pressure and grouting rate during the test is strong. Under hydrodynamic conditions, the grouting slurry diffuses elliptically. Due to gravity and the effect of the upper water flow, the center of gravity of the ellipsoid is below the grouting outlet, and the grouting effectively improves the physical and mechanical properties of water-rich sand bodies. At the same time, the resistivity method has a good application effect on the detection of grouting diffusion range. The range of slurry diffusion obtained by the resistivity method is basically consistent with the boundary of the stone body after excavation, indicating that the resistivity method is reliable for detection of grouting range in dynamic water-rich sand layer. © 2018, Editorial Office of "Modern Tunnelling Technology". All right reserved. 相似文献
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