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251.
大鼠海马神经元自发放电对皮下注射福尔马林的反应 总被引:1,自引:0,他引:1
采用玻璃微电极细胞外记录法,观察了清醒完整大鼠海马神经元自发放电对皮下注射福尔马林的反应。结呆显示,在海马CA2/CA3区可记录到痛兴奋、痛抑制和非痛敏三种神经元。同侧前爪皮下注射福尔马林后,痛兴奋神经元的自发放电显著增多,而痛抑制神经元的自发放电显著减少,这种变化在给予福尔马林后30min左右达到最大值,在60min左右恢复到对照水平;但在给予福尔马林后,非痛敏神经元的自发放电无明显变化。以上实验结果提供了在福尔马林痛模型中,海马在痛感受或痛反应过程中发挥一定作用的电生理证据。 相似文献
252.
铁道车辆通过辙叉时的垂向动力模拟计算 总被引:2,自引:3,他引:2
在车辆-轨道垂向系统统一模型的基础上,提出铁道车辆-辙叉相互模型。对道岔结构作一定的简化处理,针对道岔垂向几何不平顺,运用轮轨系统耦合动力学理论,模拟计算得到车辆通过道岔辙叉时的轮轨冲击力以及车体、辙叉、岔枕和道床等振动响应。模拟结果显示:辙叉叉心处的不平顺空间,是直接影响轮轨冲击力的部位,它可以引起较大的轮轨冲击力,并引起车辆与轨下基础结构振动。 相似文献
253.
Carlos Jerome Lawrence A. Howard Ezgi Uzel Jameela R. Androulidakis 《WMU Journal of Maritime Affairs》2017,16(1):89-98
Protection against on-ship infectious disease—whether due to mishap or to harmful purpose—faces special situational problems. Sometimes, when infection levels on board have reached threshold levels, emergency actions are required. Often, the most thorough strategies for responding to threat are not feasible. A rapid first-stage test (RFT) is a fast, minimally invasive procedure used to rule out from possible infection a large percentage of an infection-threatened group. Prevention and control of on-ship infection need to combine various interconnected tactics. When timely criterion tests are not possible, the medical team must adopt fast alternative measures. The methods used to summarize protection against on-ship infectious agents included a scientific literature review and a web search. The fields of the review were maritime, health, and technology sources. Special attention was paid to material dealing with risks and threats of on-ship penetration by infectious agents, on-ship infection prevalence thresholds, and rapid diagnostic screens. The Bayes rule and the law of large numbers were applied to the analysis, for large on-ship populations, of RFT indications of crossing of an infection prevalence threshold. The increasing risk of serious on-ship infection—either accidental or purposeful—calls for a multi-layered protection approach. RFTs are a key part of the outer layer of such a defense. Well-designed and well-administered RFTs provide several advantages for defense against on-ship infection: low-cost, non-invasive, fast, and focuses on a drastically smaller number of infection possibilities. 相似文献
254.
Michael Ekow Manuel 《WMU Journal of Maritime Affairs》2017,16(3):473-483
Traditional seafarer training has always focused on the acquisition and use of practical skills. The prevailing view is that, while this approach addresses a degree of cognitive skills, it focuses on and gives much more emphasis to the acquisition of hands-on practical skills for the performance of specific tasks. On the other hand, academic education has been seen to be much more focused on the development of in-depth analytical and critical thinking skills; cognitive skills that are less reliant on hands-on task-oriented training, but stress critical reading and discussion. The global trend in maritime education and training is increasingly to link an essentially vocational education that provides specific and restricted competence outcomes with more general or deeper academic components leading to an academic qualification. This trend has led to some dilemmas for curriculum development, for training legislation in a global industry, and for achieving desired learning outcomes in a professional setting (in the shipping industry). This paper discusses some of the challenges arising from this trend and the opportunities the trend offers. 相似文献
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Full-scale globalisation of trade has been accompanied by a progressive liberalisation of maritime transport. The proliferation of open registries has created a situation in which Port State Control (PSC) has become much more effective than the feeble or non-existent control exercised by those States. This study has been conducted on the influence of the professional profile of inspectors on inspection results. The objective of our paper was to evaluate the impact of PSC inspectors’ professional profile by conducting a case study of the Spanish Maritime Administration. The paper concludes with a discussion of the correlation between deficiencies detected and professional profiles. 相似文献
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