基于内力包络的桥梁健康监测数据分析

对基于内力包络的桥梁健康监测数据进行了分析研究.首先,介绍了内力包络的方法;然后,对实桥健康监测数据进行了分析,采用校验系数包络法、挠度包络法、容许应力包络法对其进行了进一步分析;最后,得到内力包络法对桥梁健康监测数据集桥梁健康状况的相应结论.该分析方法,可为同类桥梁健康监测数据的分析及桥梁健康状况的评价提供一定的依据.     

乙型肝炎病毒基因型检测及其与肝功能的关系

目的 探讨乙型肝炎病毒基因型与肝功能的关系.方法 采用微板核酸分子杂交ELISA法检测93例不同临床类型的乙型肝炎患者的基因型并同时测定肝功能.结果 93例不同临床类型乙型病毒性肝炎患者中,B型24例(25.81%),C型59例(63.44%),D型5例(5.38%),混合型5例(B/D 3例,C/D 2例,占5.38%).93例不同临床类型的乙型肝炎患者中,以C基因型为主,其次为B基因型,部分以D型和混合型存在,无A、E、F型.按照慢性乙型肝炎、亚急性重型肝炎、肝硬化的顺序,C基因型的检出率逐渐增多,B基因型的检出率逐渐减少.肝癌患者C基因型的检出率没有依次增高.C基因型各型乙型肝炎患者的ALT、AST、TBIL均高于B型,ALB低于B型,但差别无统计学意义.结论 西安地区病毒性肝炎以C基因型为主,部分以B、D及混合型存在,未发现A、E、F型.除肝癌外,C型的检出率随临床类型的加重而增多.     

Screening of hepatocyte proteins binding to NS5ABP37 protein by yeast-two hybrid system

Objective To investigate the biological function of NS5ABP37 and to look for proteins interacting with NS5ABP37 protein in hepatocytes. Methods We constructed bait plasmid expressing NS5ABP37 protein of hepatitis C virus (HCV) by cloning the gene of NS5ABP37 protein into pGBKT7, then the recombinant plasmid DNA was transformed into yeast AH109 (α type). The transformed yeast AH109 was mated with yeast Y187 (α type) containing liver cDNA library plasmid in 2×YPDA medium. Diploid yeast was plated on synthetic dropout nutrient medium (SD/-Trp-Leu-His-Ade) containing X-α-gal for selection and screening. After extracting and sequencing of plasmids from positive (blue) colonies, we made a sequence analysis by bioinformatics. Results We screened twenty-five proteins binding to NS5ABP37, including Homo sapiens cyclin Ⅰ (CCNI) gene, Homo sapiens matrix metallopeptidase 25 (MMP25) and Homo sapiens talin 1. Conclusion The yeast-two hybrid system is an effective method for identifying hepatocyte proteins interacting with NS5ABP37 of HCV. And the biological function of NS5ABP37 may be associated with glycometabolism, lipid metabolism and apoptosis.     

高温高压液压脉动综合性能试验台的设计

为了满足企业的测试技术要求,文章提出了应用计算机监控系统的高温高压液压脉动综合性能试验台的设计方案,采用了PQE5P6溢流阀和电液伺服元件等性能良好的元器件,解决了测试数据的采集和抗干扰技术,开发了在Windows平台上操作的测试软件,实现了对测试参数的自动纪录、分析、曲线绘制、显示、打印和集中的控制等功能。     

色彩在沥青类路面铺装中的运用

色彩是彩色铺装的灵魂。简要介绍色彩的基本属性和特性,分析色彩的意向和用途,阐述、归纳现阶段一些沥青类彩色路面的主流着色方案和铺装方案,以期对广大彩色路面设计研究人员提供帮助。     

Belt routing and safety assessment through computer simulation

Most of the research on safety belt systems has involved crash simulation that only considered a dynamic human model. However, belt routing analysis, usually known as comfort level estimation, is also an important factor in safety belt design, considering that serious injuries of the abdominal region result from the infiltration of a belt into the neck or the chest. Thus, safety belt evaluations using kinematic human models are also needed. In this paper, a belt fit simulation method is suggested. Using the proposed process, both comfort and safety analyses can be performed under the same conditions continuously, and thus the safety belt design parameters, such as the location of anchor points, dummy posture and etc., can be evaluated. In conclusion, this computer process enables a belt system design to reduce injuries.     

Grain refinement in bearing steels using a double-quenching heat-treatment process

A double-quenching (D/Q) process is proposed for heat-treating high carbon-chromium bearing steels to improve the fatigue properties through refinement of the microstructure. The new heat treatment method has two steps: The first step is a nitrocarburizing process that results in high surface hardness and lowers the transformation temperature. The second step is the same as in the conventional quenching process but can be conducted at a considerably lower temperature than in conventional quenching. The microstructure in the material that is caused by the D/Q heat treatment is much finer than in the conventional Q/T (quenching and tempering) process. In order to quantify the performance of the proposed heat-treatment process, various mechanical property tests are carried out. The rolling contact fatigue life of double-quenched bearing steels was eight times higher than in bearing steels that were treated by conventional Q/T.     

变速器齿轮传递误差分析与优化

介绍了一种降低变速器啸叫的方法,即通过齿轮修形降低齿轮传递误差.本文分析某变速器第5挡齿轮的传递误差,发现传递误差值偏大,并且齿面载荷分布不合理.根据齿面载荷分布对齿轮进行了修形,修形后齿面单位长度载荷从484 N/mm降低到了339 N/mm,传递误差值从5.17 μm降低到0.12μm,为变速器啸叫问题的改善提供了依据.     

机非混行环境下驾驶员行为建模及仿真

运用冲突点法分析了自行车对机动车驾驶员行为的影响,将冲突模型转化为一种特殊的车辆跟驰或车道变换来研究,并进行了机非混行复杂环境下驾驶员行为的仿真建模和试验验证.结果表明:用冲突点法进行驾驶员行为仿真,其结果与实际观测数据基本一致,试验结果的拟合率和误差率都在理想范围内;冲突点法是机非混行环境下驾驶员行为建模的可行方法.研究结果为深入分析多源信息刺激下驾驶员协同行为提供了理论基础.     

下承式钢管混凝土拱桥稳定性研究

以某下承式钢管混凝土拱桥为工程背景,对成桥阶段自重作用下结构的稳定性进行研究.在线弹性稳定分析中,使用4种方法对拱肋结构刚度进行模拟,所得的稳定系数随拱肋计算刚度而不同,且变化幅度较大.建议把失稳分析同变形计算结合考虑,并偏安全地取较小的稳定系数.在非线性稳定分析中,采用钢管混凝土统一理论来考虑拱肋的材料非线性,并引入几何缺陷的影响.双非线性分析表明拱肋的几何非线性效应不明显,引起结构失稳的主要因素是材料非线性.