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121.
LEISHMANIAPROMASTIGOTESEVADEINTERLEUKIN12INDUCTIONBYMACROPHAGESANDSTIMULATEABROAD RANGEOFCYTOKINESFROM CD_(4)~(+)TCELLSDURINGI...  相似文献   
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In view of their excellent mechanical properties, workability and heat treatment characteristics, MDN 138 & MDN 250 have been widely used in missile, rocket and aerospace industries. With light weight and high performance characteristics HE 20 aluminium alloy acts as an important material in defence and aerospace applications. The galvanic corrosion behaviour of the metal combinations HE 20 / MDN 138 and HE 20 / MDN 250, with 1:1 area ratio, has been studied in natural seawater using the open well facility of CECRI’s Offshore Platform at Tuticorin for a year. The open circuit potentials of MDN 138, MDN 250 and HE 20 of the individual metal, the mixed potential and galvanic current of the couples HE 20 / MDN 138 and HE 20 / MDN 250 were periodically monitored throughout the study period. The calcareous deposits on MDN 138 and MDN 250 were analysed using XRD. The results of the study reveal that that HE 20 has offered required amount of protection to MDN 138 & MDN 250.  相似文献   
123.
Full-scale globalisation of trade has been accompanied by a progressive liberalisation of maritime transport. The proliferation of open registries has created a situation in which Port State Control (PSC) has become much more effective than the feeble or non-existent control exercised by those States. This study has been conducted on the influence of the professional profile of inspectors on inspection results. The objective of our paper was to evaluate the impact of PSC inspectors’ professional profile by conducting a case study of the Spanish Maritime Administration. The paper concludes with a discussion of the correlation between deficiencies detected and professional profiles.  相似文献   
124.
This paper presents a probabilistic delay model for signalized intersections with right‐turn channelization lanes considering the possibility of blockage. Right‐turn channelization is used to improve the capacity and to reduce delay at busy intersections with a lot of right‐turns. However, under heavy traffic conditions the through vehicles will likely block the channelization entrance that accrues delay to right‐turn vehicles. If the right‐turn channelization gets blocked frequently, its advantage in reducing the intersection delay is neglected and as a result the channelization lane becomes inefficient and redundant. The Highway Capacity Manual (HCM) neglects the blockage effect, which may be a reason for low efficiency during peak hours. More importantly, using HCM or other standard traffic control methods without considering the blockage effects would lead to underestimation of the delay. To overcome this issue, the authors proposed delay models by taking into account both deterministic and random aspects of vehicles arrival patterns at signalized intersections. The proposed delay model was validated through VISSIM, a microscopic simulation model. The results showed that the proposed model is very precise and accurately estimates the delay. In addition, it was found that the length of short‐lane section and proportion of right‐turn and through traffic significantly influence the approach delay. For operational purposes, the authors provided a step‐by‐step delay calculation process and presented approach delay estimates for different sets of traffic volumes, signal settings, and short‐lane section lengths. The delay estimates would be useful in evaluating adequacy of the current lengths, identifying the options of extending the short‐lane section length, or changing signal timing to reduce the likelihood of blockage. Copyright © 2016 John Wiley & Sons, Ltd.  相似文献   
125.
Using the UK National Travel Survey from 2002 to 2006, this paper investigates the influence of households’ residential self-selectivity, parents’ perceptions on accessibilities and their travel patterns on their children daily travel mode share. In doing this, this study introduces a model structure that represents the complex interactions between the parents’ travel patterns, their perceptions on public transport services and their reported residential self-selectivity reasons and the children travel mode shares. This structure is analysed with structural equation modelling. The model estimation results show that parents’ residential self-selectivity, parents’ perceptions and satisfactions on accessibilities and their daily travel patterns significantly influence the children’s daily travel mode shares. However, the effects are not uniform across household members. This study has revealed that households’ residential self-selectivity behaviours have more correlations with the children’s non-motorised mode shares, whilst the parents’ perceptions and satisfactions on transport infrastructure and public transport service qualities have more correlations with parents’ mode shares. The results also confirm that parents’ non-motorised modes use in travelling is highly correlated with the children’s physically active travel mode shares. However, at the same time, the results also show that the effects of mothers’ car use to the children travel mode shares is more apparent than fathers’.  相似文献   
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Accurate and efficient contact models for wheel–rail interaction are essential for the study of the dynamic behaviour of a railway vehicle. Assessment of the contact forces and moments, as well as contact geometry provide a fundamental foundation for such tasks as design of braking and traction control systems, prediction of wheel and rail wear, and evaluation of ride safety and comfort. This paper discusses the evolution and the current state of the theories for solving the wheel–rail contact problem for rolling stock. The well-known theories for modelling both normal contact (Hertzian and non-Hertzian) and tangential contact (Kalker's linear theory, FASTSIM, CONTACT, Polach's theory, etc.) are reviewed. The paper discusses the simplifying assumptions for developing these models and compares their functionality. The experimental studies for evaluation of contact models are also reviewed. This paper concludes with discussing open areas in contact mechanics that require further research for developing better models to represent the wheel–rail interaction.  相似文献   
129.
Improper clamping of wiper arms can cause problems in the operation of the wiper. An excessive clamping force can cause damage to the wiper arm head. On the other hand, an insufficient clamping force can cause self-loosening of the nut. Given the lack of direct research on the clamping force of the fastener in wiper assembly, this study verifies the existing clamping performance of the fastener in windshield wiper assembly by theoretical and experimental methods. The theoretical calculation results show that all the clamping performance are satisfied under the general snow load condition. However, under the critical load condition, maximum assembly preload and safety margin against slipping are in disagreement with the standard values. This problem is solved by increasing the strength grade of the bolt. The experimental results show a reducing tendency of the clamping force during the snow durability test. However, this reducing clamping force during the 60,000 test cycles is acceptable. In the case of nut reusing more than two times possibly cause a problem of its loosening because of insufficient clamping force. Therefore, it is recommended that the nut should not be reused more than two times.  相似文献   
130.
In diesel engine, spray penetration is usually changed by in-cylinder gas flow. Accurate prediction on diesel spray with gas flow is important to the optimal design of diesel fuel injection system. This paper presents a theory investigation focusing on the penetration of diesel spray with gas flow. In order to understand the effect of gas flow on the penetration of diesel spray, a one-dimensional spray model is developed from an idealized diesel spray, which is able to predict the spray behavior under different gas flow conditions. The ambient gas flow is simplified as ideal flow that has only constant flow velocity along x-axial and y-axial directions of spray. The x-axial and y-axial directions are respectively defined as along and vertical spray directions. The main assumption is that the y-axial direction gas flow has no effect on the penetration of spray along x-axial direction. The principles of conservation of mass and momentum are used in the derivation. Momentum of in-cylinder air flow is also taken into consideration. Validation of the model at stable condition is achieved by comparing model predictions with experimental measurements of diesel spray without gas flow from Naber's experiments. Furthermore, CFD simulations on penetration of diesel spray with gas flow were performed with the commercial code AVL-fire. The onedimensional model is validated by the penetration results with gas flow from CFD calculation. Results show that a reasonable estimation of the spray evolution can be obtained for both with and without ambient gas flow conditions.  相似文献   
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