原位自生(TiC+TiB)/Ti6Al4V在300℃干滑动摩擦磨损机制

选用颗粒状TiC和条状TiB复合增强的钛基复合材料,在300℃环境温度和不同载荷下的干滑动摩擦磨损行为及其磨损机制进行研究.利用SEM、ESS、XRD等分析手段,对磨损面、剖面,磨屑等进行观察与分析;总体上复合材料磨损率降低,且增强相含量高的磨损率也低,摩擦系数小而稳定.磨损表面存在氧化物,存在磨屑脱落后的痕迹,从磨损...     

双电机电动助力转向系统在无人驾驶小型客车上的应用

介绍双电机电动助力转向系统的组成、功能,以及其在4m无人驾驶客车上的应用情况.     

纯电动客车特殊工况下传动系NVH的性能试验研究

对某10 m纯电动客车传动系进行加速和制动工况下的NVH性能试验研究,为纯电动客车的NVH性能改善提供参考.     

DIFFERENTIAL EXPRESSION OF GENES IN OMENTAL FAT OF NORMAL WEIGHT AND OBESE SUBJECTS AND OBESE DIABETIC PATIENTS USING cDNA MICROARRAY

Objective To identify genes differentially expressed in omental fat of normal weight subjects,obese subjects and obese diabetic patients. Methods Using a high-density cDNA microarray, gene expression profile of omental fat from normal weigh subjects, obese subjects and obese diabetic patients were compared.Results Totally, 119 and 257 genes were up-regulated in obese subjects and obese diabetic patients respectively,while 46 and 58 genes were down-regulated. A total of 77 genes, including PDK4, which switched from carbohydrate to fatty acids as the primary source of fuel, were up-regulated in both obese and obese diabetic patients, while 8 genes, including key enzymes in lipid synthesis, such as HMG-CoA synthase, fatty acid synthase and stearoyl-CoA desaturase, were down-regulated in both groups. Tyrosine-3-monooxygenase/tryptophan 5-monooxygenase activation protein θ ( YWHAZ) , a negative regulator for insulin signal transduction, was up-regulated only in obese diabetic patient, but not in normal-glycemic obese subjects. Conclusion The study demonstrated that decrease of lipogenesis along with increase of fatty acids oxidation of adipose tissue could be a common cause of insulin resistance in obesity and type 2 diabetes, while block of insulin signal transduction may trigger the transition from obesity to diabetes. Further exploration of these genes will be useful in the understanding of the pathogenesis of obesity and diabetes.     

INTRAOPERATIVE LOCALIZATION OF CORTICAL MOTOR EVOKED POTENTIALS IN CENTRAL SULCUS LESIONS

Objective To study direct cortical electrical stimulation technique for the recording of motor evoked potentials under general anesthesia in central sulcus lesions. Methods The largest N20-P25 response was recorded from postcentral gyrus by intraoperative monitoring of cortical motor evoked potentials in 10 patients with intracranial lesions near or in the central area. The muscles of upper extremity in all patients were activated by delivering stimulus to cortical areas continuously. Moving the cortical electrodes forward, the largest P20-N25 response, SEP phase reversal,was obtained as a motor center stimulus. In this site of cortex, a short train stimulation elicited reproducible muscle action potentials that could be observed from the oscilloscope without averaging.Results MEPs can be recorded, pre- and post-operatively, without motor deficits of upper limbs in all patients.Conclusion This technique seems to be preferable for intraoperative localization of motor evoked potentials in central sulcus lesions under total intravenous anesthesia.     

SIMPLE METHOD OF PUNCHING AND RE-LOCATING TISSUES FOR MANUAL CONSTRUCTION OF TISSUE MICROARRAY

A series of human tissue samples and cultured cell lines were formalin-fixed and paraffin-embedded. Specimen cylinder ( 1.2 - 1.8mm) were punched by a modified bone marrow biopsy needle and arrayed on a recipient paraffin block. Microscopic analysis on the sections from this tissue microarray (TMA) block demonstrated that the spots of tissues and cells were well preserved, and the cultured cell samples were successfully embedded from 5 × 104 to 2 × 105 in number. These TMA sections were also suitable for immunohistochemistry and RNA in situ hybridization.     

Effects of Dynamic Changes in Ultrasound Attenuation and Blood Perfusion on Lesion Formation of Multiple focus Pattern during Ultrasound Surgery

A nonlinear finite-element program was developed to simulate the dynamic evolution of coagulation in tissue considering temperature and thermal-dose dependence of the ultrasound attenuation and blood perfusion rate.The effects of these dynamic parameters on the lesion formation were investigated in the particular case of ultrasound hepatic ablation with bi-focus intensity pattern.The results of simulations were compared that incorporate dynamic changes of ultrasound attenuation and perfusion and results that neglect these effects.The result shows that thermal-dose-dependent ultrasound attenuation is the dominating factor in the full dynamic model.If the dynamic ultrasound attenuation is ignored, a relatively significant underestimation of the temperature rise appears in the focal plane and the region next to the focal plane, resulting in an underestimation in predicting diameter of coagulation.Higher heating intensity leads to greater underestimation.     

Secure Authentication of WLAN Based on Elliptic Curve Cryptosystem

The security of wireless local area network (WLAN) becomes a bottleneck for its further applications. At present, many standard organizations and manufacturers of WLAN try to solve this problem. However, owing to the serious secure leak in IEEE802.11 standards, it is impossible to utterly solve the problem by simply adding some remedies. Based on the analysis on the security mechanism of WLAN and the latest techniques of WLAN security, a solution to WLAN security was presented. The solution makes preparation for the further combination of WLAN and Internet.     

Investigation of Wall Pressure Fluctuations in a Turbulent Boundary Layer by Large Eddy Simulation

Large eddy simulation (LES) was used to investigate the space-time field of the low Mach number, fully developed turbulent boundary layer on a smooth, rigid flat plate. The wall-pressure field simulated by LES was analyzed to obtain the pressure statistics, including the wall-pressure root-mean square, skewness and flatness factors, which show the wall pressure distribution was not Gaussian. The profile of the auto-power spectral density and the contour of the streamwise wavenumber-frequency spectral density of wall-pressure were plotted. The "convection ridge" can be observed clearly and the convection velocity can be calculated from the location of the convection peak.     

论技术创新的风险利益原理与金融支持的必要性

本文研究认为,技术创新的动力基础在于其风险利益。即技术创新风险本质上是一种风险利益,经济主体之所以愿意承担技术创新巨大的风险,原因就在于技术创新背后巨大的风险利益。而这一理论,为技术创新金融支持等制度安排提供了依据与设计指导。基于上述分析本文建立了包含金融要素的技术创新动力机制模型。