DESIGN OF A DIGITAL SIGNATURE SCHEME BASED ON FACTORING AND DISCRETE LOGARITHMS

Objective Focusing on the security problem of authentication and confidentiality in the context of computer networks, a digital signature scheme was proposed based on the public key cryptosystem. Methods Firstly,the course of digital signature based on the public key cryptosystem was given. Then, RSA and ELGamal schemes were described respectively. They were the basis of the proposed scheme. Generalized ELGamal type signature schemes were listed. After comparing with each other, one scheme, whose Signature equation was (m r)x=j s modФ(p) , was adopted in the designing. Results Based on two well-known cryptographic assumptions, the factorization and the discrete logarithms, a digital signature scheme was presented. It must be required that s“ was not equal to p‘q“ in the signing procedure, because attackers could forge the signatures with high probabilities if the discrete logarithms modulo a large prime were solvable. The variable public key “e“ is used instead of the invariable parameter “3“ in Ham‘s signature scheme to enhance the security. One generalized ELGamal type scheme made the proposed scheme escape one multiplicative inverse operation in the signing procedure and one modular exponentiation in the verification procedure.Conclusion The presented scheme obtains the security that Harn‘s scheme was originally claimed. It is secure if the factorization and the discrete logarithms are simultaneously unsolvable.     

THE GENE EXPRESSION OF BDNF IN NORMAL RABBIT RETINA

Objective To investigate the distribution of brain-derived neurotrophic factor(BDNF) protein in the rabbit retina. Methods Immune response material in the retina was observed using BDNF antibody by the method of immunohistochemistry. Results BDNF gene expression was mainly found in the RGCs, also in innernuclei cells and outernuclei cells in rabbit retina. Conclusion RGC is not only the target cell of BDNF, but also express the BDNF protein. BDNF from multi-sources participates in the regulation of RGCs.     

结节性痒疹皮损中P物质、降钙素基因相关肽的表达

目的　探讨降钙素基因相关肽 (CGRP)、P物质 (SP)在结节性痒疹发病中的作用。方法　采用免疫组化SABC法 ,检测 30例结节性痒疹患者的皮损、非皮损区以及 15例正常人皮肤中CGRP和SP的分布和表达。结果　CGRP和SP在结节性痒疹皮损全层皮肤中均有表达 ,呈环胞膜着色 ;在正常表皮和非皮损区中有轻度表达 ;在结节性痒疹皮损区CGRP和SP表达 ,与正常对照及未受累皮肤比较有显著性差异 (P <0 .0 1)。结论　神经多肽与结节性痒疹的发病有关 ,其可能通过免疫介导促进疾病的形成发展     

β淀粉样肽1～42单克隆抗体的制备

目的　制备稳定分泌β -淀粉样肽 1～ 4 2 (Aβ1-42 )单克隆抗体的杂交瘤细胞 ,产生高效价抗体。方法　通过基因工程技术 ,将Aβ1-42 基因融合于乙肝核心抗原 (HBcAg)的主要免疫优势区 (MIR) ,制备Aβ和HBcAg的融合蛋白 ,免疫BALB/c小鼠 ,取脾细胞与SP2 / 0细胞融合 ,筛选能稳定分泌Aβ1-42 单克隆抗体的杂交瘤细胞。结果　得到两株能稳定分泌Aβ1-42 单克隆抗体的杂交瘤细胞 ,Aβ1-42 单克隆抗体的Ig亚类为IgG3 。结论　制备得到的Aβ1-42 单克隆抗体特异性强 ,效价高     

大鼠耳蜗α_(1D)L-型电压门控钙通道组织特异性异构体的剪切方式及其意义

目的　研究α1DL 型电压门控钙通道基因在大鼠耳蜗的剪切 (splicing )方式及其意义。 方法　以显微解剖取材的大鼠耳蜗基底膜为起始材料 ,利用外显子特异性 (exon specific)引物的RT PCR扩增和序列测定确定耳蜗表达的α1DL 型电压门控钙通道的剪切方式。结果　耳蜗表达的α1D钙通道cDNA剪切部位发生在功能域Ⅰ、Ⅱ之间的细胞内连接区和羧基末端。结论　大鼠耳蜗存在α1D钙通道组织特异性的剪切异构体 ,选择性剪切可能是内耳基因表达调控的重要机制     

Dynamic investigation on composite flexible multi-body system considering thermal effect

The dynamic performance of composite flexible multi-body system under the simultaneous action of thermal fields and driving constraint is analyzed. Based on strain-displacement relation of the Mindlin plate theory which includes transverse shear deformation, and considering thermal effect, variation equations of laminated plate are derived by the principle of virtual work. The finite element method is used for discretization. According to kinematics constraint relation, dynamic equations for spatial slider-crank system are established. Simulation results show that spatial deformation (torsion deformation) appears in the multi-layered composite slider-crank mechanism which is simulated with planar motions. Furthermore, the influence of coupling between thermal expansion and flexible deformations of non-symmetrical composite plates on the large overall motion under the uniform temperature field is investigated. Finally, significant change in constraint force due to the spatial deformation is shown.     

Feasibility study for the application of air inflated membrane structure in China National Stadium

China National Stadium, also known as “Bird’s Nest”, is the main stadium of the 29th Olympic Games in Beijing in 2008, which has successfully held not only the Opening and the Closing ceremonies but also the track and field events. A new problem of rain preventing is brought out to improve the utilization of the Bird’s Nest after the Olympic Games. The scheme of installing an air inflated membrane at the opening of the steel structure is proposed in this paper to solve the rainproof problem of the Bird’s Nest. The form-finding and mechanical analyses of the air inflated membrane are carried out. Comparison between the mechanical performance and dynamical character before and after installing the air inflated membrane structure is given. To verify the analysis results, based on the practical structure of the Bird’s Nest, a test of a 1:20 model membrane is worked out.     

Face recognition via adaptive image combination

Dimension reduction and manifold learning are the two most popular feature extraction methods. The two methods focus on spatial locality as a guiding principle to find a low-dimensional basis for describing high-dimensional data, but no bases or features are more spatially localized than the original image pixels. So, adaptive image combination is presented to represent a class by a combined sample. The combined sample is a linear combination of original samples in the same class. Adaptive image combination (AIC) find the best combination coefficients by minimizing the intrapersonal distance and maximizing the interpersonal distance. Experimental results show that AIC is effective.     

Novel mesh technique and its application in the wind field simulation for flexible spatial structure

In this paper, novel mesh techniques are proposed for wind field simulation of flexible spatial structure. For mesh generation, an interpolation strategy is presented to obtain a mesh system with variable density. Two spatial structure examples are used to examine the efficiency and applicability of this technique. Then based on the structured mesh system generated by the technique, the mesh nodal coordinates are updated to adapt the moving boundary conditions by means of the mapping interpolation functions and some examples are given to verify the effectiveness. Furthermore, the constrained counterforce distribution technique and projection interpolation strategy are developed to implement the data exchange on the interaction surface of wind and structure. Finally, the computational accuracy is numerically validated.     

Numerical analysis and experimental study of the effect of workpiece thickness on flow field in laser cutting

Based on Navier-Stokes equation and renormalization group (RNG) onflow model, the 3D symmetrical impinging jet model of laser cutting is established by adopting a taper nozzle and a convergence nozzle. Numerical simulation of gas flow in laser cutting is used to investigate the effect of workpiece thickness on flow field of assist gas in cutting slot. The isolines of static pressure as well as the distributions of static pressure and velocity are analyzed in details with different workpiece thickness, and the trend of dynamics characteristics of gas jet is shown in the study. For taper nozzles and convergence nozzles, the dynamic structure of assist gas being close to the lower surface of workpiece is exacerbated while the cutting quality and cutting efficiency become worse with the increasing of workpiece thickness. The parallel degree between assist gas and the axis of convergence nozzle is better than that of taper nozzle after the gas goes out of the nozzles. Two typical subsonic nozzles are designed for the cutting experiment at the end of the paper.