Modeling research on manufacturing execution system based on large-scale system cybernetics

A cybernetics model of manufacturing execution system(MES CM) was proposed and studied from the viewpoint of cybernetics.Combining with the features of manufacturing system, the MES CM was modeled by"generalized modeling"method that is discussed in large-scale system theory.The mathematical model of MES CM was constructed by the generalized operator model, and the main characteristics of MES CM were analyzed.     

A data model applied to the knowledge-based ICAS

Image-guided computer aided surgery system (ICAS) contributes to safeness and success of surgery operations by means of displaying anatomical structures and showing correlative information to surgeons in the process of operation. Based on analysis of requirements for ICAS, a new concept of clinical knowledge-based ICAS was proposed. Designing a reasonable data structure model is essential for realizing this new concept. The traditional data structure is limited in expressing and reusing the clinical knowledge such as locating an anatomical object, topological relations of anatomical objects and correlative clinical attributes. A data structure model called mixed adjacency lists by octree-path-chain (MALOC) was outlined, which can combine patient's images with clinical knowledge, as well as efficiently locate the instrument and search the objects' information. The efficiency of data structures was analyzed and experimental results were given in comparison to other traditional data structures. The result of the nasal surgery experiment proves that MALOC is a proper model for clinical knowledge-based ICAS that has advantages in not only locating the operative instrument precisely but also proving surgeons with real-time operation-correlative information. It is shown that the clinical knowledge-based ICAS with MALOC model has advantages in terms of safety and success of surgical operations, and help in accurately locating the operative instrument and providing operation-correlative knowledge and information to surgeons in the process of operations.     

Analysis and improvement of authenticatable ring signcryption scheme

We show that the Zhang-Yang-Zhu-Zhang identity-based authenticatable ring signcryption scheme is not secure against chosen plaintext attacks.Furthermore, we propose an improved scheme that remedies the weakness of the Zhang-Yang-Zhu-Zhang scheme.The improved scheme has shorter ciphertext size than the Zhang-Yang-Zhu-Zhang scheme.We then prove that the improved scheme satisfies confidentiality, unforgeability, anonymity and authenticatability.     

Power network parameter estimation method based on data mining technology

The parameter values which actually change with the circumstances, weather and load level etc.produce great effect to the result of state estimation. A new parameter estimation method based on data mining technology was proposed. The clustering method was used to classify the historical data in supervisory control and data acquisition (SCADA) database as several types. The data processing technology was impliedto treat the isolated point, missing data and yawp data in samples for classified groups. The measurement data which belong to each classification were introduced to the linear regression equation in order to gain the regression coefficient and actual parameters by the least square method. A practical system demonstrates the high correctness, reliability and strong practicability of the proposed method.     

The role of interleukin-8 produced by tumor induced fibroblasts in the development of cutaneous melanoma

Objective To determine the role of interleukin-8 (IL-8) produced by tumor induced fibroblasts in the development of cutaneous melanoma. Methods B16 melanoma cells induced L929 fibroblasts phenotype was transdifferentiated to myofibroblasts (MF) by co-culture in vitro. MF was monitored by morphology and immunophenotype for a-SMA. The level of IL-8 was detected by ELISA. The effect on B16 cell proliferation rate was estimated using MIT method in vitro. Melanoma implanting model was constructed in C57 mice. Results L929 MF phenotype could be modulated by B16 melanoma cells-derived transforming growth factor-β1 (TGF-β1) and elevated the levels of IL-8. L929 MF did not influence the B16 melanoma cells viability in vitro, but shortened the time of tumor formation and increased the incidence rates of tumors in C57 implanting model mice. Conclusion Fibroblasts can be activated by tumor cells and produce IL-8, which acts as an inflammatory cytokine promoting the development of cutaneous melanoma.     

Effect of ABCA1-V771M polymorphism on plasma lipid levels and its relationship with coronary atherosclerotic heart disease

Objective To explore the risk association of ABCA1-V771M polymorphism with coronary heart disease (CHD) in Hart nationality in Northwest of China. Methods With case-control study, ABCA1-V771M polymorphism was detected in 204 unrelated Hart nationality people in Northwest of China, and all the subjects by coronary angiography were grouped into 106 cases and 98 controls. The genotypes and alleles frequency distribution of ABCA1-V771M polymorphisms were analyzed by PCR-RFLP analysis, and the clinical statistics of serum lipids were compared and its effects of ABCA1-V771M polymorphism on the plasma lipid levels and coronary atherosclerotic heart disease were analyzed. Results The genotypic frequencies of ABCA1-V771M polymorphism matched well under Hardy-Weinberg equilibrium (P>0.05), V and M allelic frequencies were 33.3% and 66.7%. In comparison with VV VM genotype carriers, MM genotypes carriers had much lower plasma levels of HDL-C (P<0. 001) and much higher plasma levels of TG (P<0. 05). M allelic frequency in CHD group was significantly higher than V allelic frequency (P<0. 05). M allele was related with more severity of atherosclerosis in the coronary artery than V allele (P<0.05). However, there was no obvious difference in the incidence of AMI among carriers with three genotypes of ABCA1-V771M polymorphism (P>0.05). Conclusion ABCA1-V771M polymorphism was not only associated with the plasma levels of HDL-C and TG, but also related to the susceptibility and severity of coronary atheroselerotic heart disease. Moreover, M771 allele appeared to be atherogenie among Han population in Northwest of China.     

沙棘果油及沙棘籽油对大鼠放射性皮肤损伤的影响

目的观察沙棘果油及沙棘籽油对大鼠放射性皮肤损伤的影响。方法实验用深部X线治疗机,每次以3000 cGy的剂量,照射两次,造成大白鼠臀部放射性皮肤损伤。待动物症状明显后,将Ⅱ度皮肤损伤的动物随机分为6组,即阴性对照组、沙棘果油高剂量组、沙棘果油低剂量组、沙棘籽油高剂量组、沙棘籽油低剂量组以及阳性对照组。沙棘果油及籽油高剂量组,每天在损伤部位涂药两次,而其低剂量组每天涂药一次,阴性对照组每天涂灭菌的注射用水一次,阳性对照组每天涂Solcoseryl-Jelly软膏一次。结果肉眼观察结果显示,连续用药10d后,沙棘果油、籽油及Sol-coseryl-Jelly组动物的局部红斑、水肿明显减轻,创面分泌物明显减少,用药2周后,上述症状明显消退,与阴性对照组比较,明显好转;另外,沙棘果油、籽油及Solcoseryl-Jelly组的创面愈合时间明显缩短。光学显微镜观察结果显示,沙棘果油、籽油及Solcoseryl-Jelly组的皮肤损伤明显减轻,炎症反应亦明显减轻,创面修复明显。电子显微镜观察结果显示,阴性对照组的超微结构明显受损,而沙棘果油、籽油及Solcoseryl-Jelly组的损伤明显减轻。结论沙棘果油及沙棘籽油对大鼠放射性皮肤损伤有明显的治疗作用。     

护栏高度变化对防撞能力影响研究

护栏高度由于路面加铺罩面而降低,使得其安全防护性能受到影响。利用LS-DYNA有限元分析软件对不同高度下波形梁护栏进行了碰撞仿真实验,量化分析了护栏高度降低与其安全防护能力关系,确定了护栏防撞性能不能满足规范要求的临界高度值。对沿海高速公路原有护栏提出改造方案,并运用计算机仿真证明其符合规范规定。     

海工产品拖拉滑移装置设计

为解决海工产品移位的难题,对海工产品的拖拉滑移技术进行研究,提出了一种拖拉滑移装置。该装置将定滑轮组集成于专用滑块上,即可进行海工产品的拖拉滑移作业。实际应用效果较好。