城市轨道交通线网突发应急事件分类分级模型研究

在现有城市轨道交通突发应急事件分类分级的基础上,对线网突发应急事件分类分级模型进行研究,提出了一种分类分级的三元组模型.对模型中应急事件的类型、关联度、等级等变量,以及模型特点进行了分析.该模型具有系统性、动态性并有利于功能的柔性分解,是智能信息推拉模式的线网应急指挥综合信息系统平台建设的基础.     

L－双Fuzzy拓扑空间中的Lindelof性质

本文以远域理论为工具引入了Ｌ－双Ｆｕｚｚｙ拓扑空间中的Ｌｉｎｄｅｌｆ性质,讨论了这类空间的一些性质。证明了Ｌｉｎｄｅｌｆ性质是闭遗传的、双强同胚不变量,最后给出了在弱诱导拓扑空间中,Ｌｉｎｄｅｌｆ性质的几个等价条件。      

柴胡皂苷d对大鼠实验性肝癌形成的预防作用

目的研究柴胡皂苷d(saikosaponin-d,SSd)对大鼠实验性肝癌形成的预防作用。方法采用间断小剂量二乙基亚硝胺(diethylnitrosamine,DEN)灌胃诱发大鼠肝癌模型,将90只清洁级雄性SD大鼠随机分为5组:正常对照组(10只)、肝癌模型组(20只)、SSd大、中、小剂量组(2.0、1.5、1.0 mg/kg,各20只),SSd治疗组在建立肝癌模型的同时,腹腔注射不同剂量的SSd,实验16周后停止给药,实验第18周处死所有大鼠,比较各组大鼠体重的改变,检测血清肝功指标丙氨酸氨基转移酶(alanine aminotransferase,ALT)、天门冬氨酸氨基转移酶(aspartate aminotransferase,AST)、碱性磷酸酶(alkaline phosphatase,ALP)、γ-谷氨酰转肽酶(γ-glutamyltransferase,GGT)、α-L-岩藻糖苷酶(alpha-L-fucosidase,AFU),并进行肝脏病理组织学检查。结果SSd各剂量组与肝癌模型组比较,血清各项肝功指标水平明显下降,差异有统计学意义,特别是SSd大剂量组(P<0.01);同时SSd治疗组与肝癌模型组相比,肝脏病理组织学镜下观察,癌细胞分化程度高,异型性低。结论SSd对大鼠实验性肝癌形成具有一定的防治作用。     

THE INVESTIGATION OF DIFFERENT POPULATION＇S TRANSFUSION-TRANSMITTED VIRUS-DNA IN SHAANXI PROVINCE

Objective To investigate transfusion transmitted virus (TTV) infection among population of different groups in Shaanxi Province. Methods A nested polymerase chain reaction (PCR) with primers from ORF1 of TTV genome was established to detect TTV-DNA in serum of the patients. Results TTV-DAN was detected in the sera of 3 of 50 cases of general population(6％), 2 of 30 cases of vocational blood donors(6.7%),21 of 97 cases with Type B hepatitis (21. 6％), 9 of 35 cases of Type C hepatitis (25. 7％),and 23 of 40 cases with non-A～ non-G hepatitis (57.5 ％ ). Conclusion There is TTV infection among general population in Shaanxi Province. TTV may be an impor- tant agent to cause non-A～non-G hepatitis. And the patients with HBV or HCV can have overlapping TTV infection.     

THE INVESTIGATION OF DIFFERENT POPULATION

［1］Nishizawa T, Okamoto H, Konishik, et al. A novel DNA Virus (TTV) associated with elevated transami-nase levels in post transfusion hepatitis of unknown eti-ology. Biochem Biophys Res Commun, 1997,741 : 92［2］Okamoto H,Nishization T, Kato N, et al. Molecular cloning and characterization of a novel DNA virus (TTV) associated with post-transfusion hepatitis of un-known etiology. Hepatology Research, 1998,10: 1［3］Leary TP ,Muerhoff AS,Simons JN, et al. Sequence and genomic organization of GBV-G:a novel member of the flaviviridae associated with human non-A-E hepatitis. J Med Virol, 1996,48 : 60［4］Alter HJ. The cloning and clinical implications of HGV and HGBV-C. NEJM,1996,334 : 1536［5］Miyakawa Y. Mayumi M. Hepatitis G virus:a true hep-atitis virus or and accidental tourist? NEJM, 1997,336 :795［6］Alter HJ,Nakatsuji Y, Melpolder J, et al. The inci-dence of transfusion-associated hepatitis G virus infec-tion and its relation to liver disease. NEJM, 1997,336: 747［7］Kao JH, Chen W, Chen PJ, et al. TT virus infection in patients with chronic hepatitis B or C :influence on clini-cal, histological and virological features, J Med Virol,2000,60(4) : 387     

正常成人神经传导远端复合肌肉动作电位参数值正常范围的建立

目的确定正常成人神经传导远端复合肌肉动作电位(CMAP)末端潜伏时和波幅的正常值范围,为诊断周围神经病提供依据。方法对245例正常健康志愿者的正中神经、尺神经、胫神经及腓总神经进行常规神经传导速度测定,分析其末端潜伏时和波幅,其结果按照不同年龄段、性别、体重、左右侧肢体分别进行统计学分析。结果性别、体重、左右侧肢体对远端CMAP参数值的影响无明显统计学差异。年龄是最主要的影响因素,40岁前后变化最大,主要影响的是各神经远端CMAP的波幅和正中神经末端潜伏时,表现为随着年龄的增大,波幅逐渐减低,末端潜伏时逐渐延长。结论正常成人远端CMAP各参数的正常值范围按40岁前后两个年龄段确定比较合理和实用。     

Association between the -1562 C/T polymorphism in the MMP-9 promoter and phenotype of esophageal squamous cell carcinoma in northern Chinese population

Objective To conduct a case-control study on the association of the nucleotide polymorphisms in the promoter region of the matrix metalloproteinase-9 (MMP-9) gene with phenotype of esophageal cancer. Methods All subjects were unrelated residents in northern regions of China. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was used to determine the MMP-9 genotypes. Results The overall distribution of genotypes in the patients was not different from that in the controls (OR=0.77, 95% CI=0.45-1.34; P=0.36). There were no significant differences between the patients and the control subjects in terms of the distributions of sex and age, smoking status, alcohol dependence, pickled diet status, or history of environmental exposure. The patients were further examined with stratifications by age, sex, grade, depth of tumor invasion, lymphatic invasion, venous invasion and TNM staging. The results showed no pronounced association among the stratifications. Conclusion There is no significant association between the MMP-9 single nucleotide polymorphism genotypes and phenotype of esophageal cancer.     

一种地铁路网应急事件分类分级方法

对现有动态模糊分类分级算法进行了分析,在轨道交通线网突发事件分类分级模型的基础上,利用层次分析和模糊决策相结合的方法,提出了一种适于地铁路网应急事件的动态模糊分类分级方法.该方法使用自学习的思想,主要包括确定关键因素综合模糊权重、动态获取关键因素值并分类分级,以及利用状态转移概率矩阵进行动态分类分级预测三部分,实现了应急事件的动态分类分级.最后给出了案例应用.     

滚筒式沥青混合料搅拌设备现场监测方法

本文根据滚筒式沥青搅拌设备的工作特点,提出了对其生产过程及生产质量的监控要求,叙述了生产现场对该设备的监控方法,特别介绍并分析了利用沥青混合料最大密度快速测定沥青含量(或油石比)方法的必要条件及可行性.     

中国西部40县农村3岁以下儿童喂养状况及影响因素分析

目的　了解中国西部贫困农村儿童的喂养特点 ,发现其存在的喂养缺陷 ,以寻找适当的干预措施 ,从而增进当地儿童的营养状况。方法　对中国西部五省区 4 0个县的农村儿童进行了抽样调查 ,共访问了 730 2户家庭。将所有资料采用EPI6 .0软件建立数据库及检错程序 ,采用两次录入法 ,用SPSS 10 .0统计软件完成所有统计分析。结果　 4 0个县儿童的喂养方式存在明显缺陷。 4个月的纯母乳喂养率较低 ;辅食的添加不合理 ,主要表现为蛋白类食品的添加严重不足 ;持续授乳直至 12个月的比例为 5 1.7% ;与国际推荐的科学喂养方式差距很大。影响当地儿童喂养方式的因素很多。民族、父母的受教育程度、家庭的收入情况、家庭孩子数及孩子的排行均明显影响到儿童的喂养行为。健康教育对儿童喂养有明显改善作用。结论　通过健康教育 ,普及科学喂养知识 ,将有助于改善西部地区儿童的喂养状况