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131.
Web page classification is an important application in many fields of Internet information retrieval, such as providing directory classification and vertical search. Methods based on query log which is a light weight version of Web page classification can avoid Web content crawling, making it relatively high in efficiency, but the sparsity of user click data makes it difficult to be used directly for constructing a classifier. To solve this problem, we explore the semantic relations among different queries through word embedding, and propose three improved graph structure classification algorithms. To reflect the semantic relevance between queries, we map the user query into the low-dimensional space according to its query vector in the first step. Then, we calculate the uniform resource locator (URL) vector according to the relationship between the query and URL. Finally, we use the improved label propagation algorithm (LPA) and the bipartite graph expansion algorithm to classify the unlabeled Web pages. Experiments show that our methods make about 20% more increase in F1-value than other Web page classification methods based on query log. 相似文献
132.
Computer-aided hip surgery planning and implant design applications require accurate segmentation of femoral head and proximal acetabulum. An accurate outer surface extraction of femoral head using marching cubes algorithm remains challenging due to deformed shapes and extremely narrow inter-bone regions. In this paper, we present an automatic and fast approach for segmentation of femoral head and proximal acetabulum which leads to accurate and compact representation of femoral head using marching cubes algorithm. At first, valley-emphasized images are constructed from original images so that valleys stand out in high relief. Otsu’s multiple thresholding technique is applied to seperate the images into bone and non-bone classes. Region growing method and threedimensional (3D) morphological operations are performed to fill holes in the bone. In the reclassification process, the bone regions are further segmented, and the boundaries of the bone regions are further refined based on Bayes decision rule. Finally, marching cubes algorithm is applied to reconstruct a 3D model and extract the outer surface of femoral head and proximal acetabulum. Experimental results show that this method is an accurate segmentation technique for femoral head and proximal acetabulum and it can be applied as a tool in medical practice. 相似文献
133.
他汀类调脂药和ACEI对急性冠脉综合征患者血清中炎性指标的影响 总被引:1,自引:0,他引:1
目的 观察他汀类调脂药和血管紧张素转化酶抑制剂 (angiotensin convertingenzymeinhibitor ,ACEI)对急性冠脉综合征患者血清中炎性指标的影响。方法 选取急性冠脉综合征 (acutecoronarysyndrome ,ACS)患者 6 0例 ,随机分为调脂治疗组和ACEI+调脂治疗组 ,在 4个月后进行随访。采用酶联免疫法测定上述病例和对照血清中一些炎性指标的水平 ,并进行统计学分析。结果 血清中某些炎性因子在ACS组中高于对照组 ,并在随访时明显降低。 4个月后所有炎性指标在调脂治疗组和ACEI+调脂治疗组之间均无显著性差异。结论 血清中某些炎性因子的水平可以作为诊断和预测ACS发生的敏感指标 ,并反应病情的稳定情况 ;ACEI药物在短期内对炎性反应的作用不明显 相似文献
134.
白细胞介素-12对哮喘患者Th细胞的作用 总被引:2,自引:0,他引:2
目的 观察白细胞介素 12 (IL 12 )对哮喘患者辅助性T淋巴细胞 (Th)的分化和细胞因子分泌的影响 ,探讨IL 12对哮喘治疗的机制及应用。方法 从哮喘患者外周血分离出单核细胞和CD4 + T(Th)细胞 ,单核细胞被尘螨变应原刺激活化后同CD4 + T细胞分别与 1μg·L-1和 5 μg·L-1IL 12共培养 ,对照组不加IL 12。 72h后收集培养上清 ,ELISA法检测IL 4、IL 5和IFN γ的生成量。培养细胞用荧光标记的单克隆抗体染色 ,流式细胞仪 (FCM)检测细胞内特异性细胞因子。结果 与对照组相比 ,实验组IL 4、IL 5的产生量明显减少 ,IFN γ的产生量显著增加 (P <0 .0 1) ,而且这种变化趋势在 1μg·L-1、5 μg·L-1IL 12间也有统计学差异 (P <0 .0 5 )。实验组Th1/Th2向Th1方向漂移 ,Th1/Th2增加 (P<0 .0 1)。结论 IL 12可调节Th的分化方向及不同类型细胞因子的分泌 ,并在一定浓度范围内呈量效依赖性。提示IL 12可作为一种新的哮喘治疗途径 相似文献
135.
甲状腺癌组织端粒酶逆转录酶和P53基因表达及其临床意义 总被引:3,自引:0,他引:3
目的 探讨端粒酶逆转录酶 (hTERT)和P5 3基因与甲状腺癌的发生、发展及预后的关系以及它们的相互关系。方法 应用免疫组织化学SP法检测 6 0例甲状腺癌、10例正常甲状腺组织、10例结节性甲状腺肿及 10例甲状腺腺瘤组织中hTERT和P5 3的表达。结果 hTERT和P5 3阳性率在甲状腺癌中增高 (P <0 .0 5 ) ;hTERT与P5 3阳性率在未分化癌、有淋巴结转移或Ⅲ、Ⅳ期病例中增高 (P <0 .0 5 ) ;hTERT表达与P5 3表达具有相关性 (P <0 .0 5 )。结论 hTERT与P5 3的过度表达在甲状腺癌的发生发展过程中具有重要作用 ,P5 3突变在转录水平上调控hTERT基因的表达 ,激活端粒酶可能是甲状腺癌发生发展的重要阶段 ;hTERT和P5 3在甲状腺癌中表达的变化可用于评估其生物学行为和判断预后。 相似文献
136.
抑郁症患者血清甲状腺激素水平变异分析 总被引:11,自引:0,他引:11
目的 了解血清甲状腺激素水平与抑郁症的关系。方法 对 6 4例门诊及住院抑郁症患者中双相抑郁障碍 34例、单相抑郁障碍 30例治疗前后血清三碘甲状腺原氨酸 (T3 )、甲状腺素 (T4)和促甲状腺激素 (TSH)进行检测 ,同时以30名健康志愿者作为对照组。治疗前后应用汉密尔顿抑郁量表 (HAMD)和Montgomery Asbery抑郁量表 (MADRS) ,评定抑郁症状的严重程度。结果 患者组治疗前后T3 [(1.98± 0 .5 2 )nmol·L-1,(1.90± 0 .5 8)nmol·L-1]均明显高于对照组 [(1.5 8± 0 .2 7)nmol·L-1],单相抑郁障碍患者治疗后T4[(93.4 1± 2 9.4 1)nmol·L-1]低于治疗前 [(10 4± 2 0 .2 4 )nmol·L-1],并恢复到正常范围 ,HAMD和MADRS评分也随之明显下降。结论 提示抑郁症患者甲状腺激素水平改变与症状的消失有关 ,甲状腺激素异常是继发于情绪障碍 ,双相抑郁障碍与单相抑郁障碍在病因学方面可能不同。 相似文献
137.
Objective To investigate the distribution of brain-derived neurotrophic factor(BDNF) protein in the rabbit retina. Methods Immune response material in the retina was observed using BDNF antibody by the method of immunohistochemistry. Results BDNF gene expression was mainly found in the RGCs, also in innernuclei cells and outernuclei cells in rabbit retina. Conclusion RGC is not only the target cell of BDNF, but also express the BDNF protein. BDNF from multi-sources participates in the regulation of RGCs. 相似文献
138.
介绍了秦皇岛港煤五期工程投入生产以来,在设备管理和保养方面的一些具体方法。指出加强对码头设备维护保养,对提高作业效率和企业竞争力的重要意义。 相似文献
139.
WIT Electronic Fuel System Co., Ltd. has developed a new fuel injector, the Electronic In-line Pump (EIP) system, designed to meet China's diesel engine emission and fuel economy regulations. It can be used on marine diesel engines and commercial vehicle engines through different EIP systems. A numerical model of the EIP system was built in the AMESim environment for the purpose of creating a design tool for engine application and system optimization. The model was used to predict key injection characteristics under different operating conditions, such as injection pressure, injection rate, and injection duration. To validate these predictions, experimental tests were conducted under the conditions that were modeled. The results were quite encouraging and in agreement with model predictions. Additional experiments were conducted to study the injection characteristics of the EIP system. These results show that injection pressure and injection quantity are insensitive to injection timing variations, this is due to the design of the constant velocity cam profile. Finally, injection quantity and pressure vs. pulse width at different cam speeds are presented, an important injection characteristic for EIP system calibration. 相似文献
140.