广西交通科技资源共享平台建设探讨

文章针对广西交通科技项目管理系统现状,分析了建设交通科技资源共享平台的必要性,阐述了交通科技资源共享平台建设的关键技术、创新点及主要内容,指出该共享平台的建设可改善和提高交通运输科技项目质量及监管水平。     

关于大学生心理健康教育课程的几点思考

大学生心理健康教育课程教学的目的是培养学生健康的心理和良好的心理素质,使其在思想认识、知识和技能三个层面学有所获。课程教学应遵循理论与实践相结合、教师讲授与学生体验相结合,通过课堂讲授、小组讨论与典型案例分析、心理素质训练与拓展等体验式教育方法进行教学;采用理论效果评估与实际操作效果评估相结合的方式对课程效果进行评估。     

Reliability Modeling and Maintenance Policy Optimization for Deteriorating System Under Random Shock

Performance degradation and random shock are commonly regarded as two dependent competing risks for system failures. One method based on effective service age is proposed to jointly model the cumulative effect of random shock and system degradation, and the reliability model of degradation system under Nonhomogeneous Poisson processes (NHPP) shocks is derived. Under the assumption that preventive maintenance (PM) is imperfective and the corrective maintenance (CM) is minimal repair, one maintenance policy which combines PM and CM is presented. Moreover, the two decision variables, PM interval and the number of PMs before replacement, are determined by a multi-objective maintenance optimization method which simultaneously maximizes the system availability and minimizes the system long-run expect cost rate. Finally, the performance of the proposed maintenance optimization policy is demonstrated via a numerical example.     

高压共轨高速电磁阀自升压双电源驱动方法研究

在对现有高压共轨高速电磁阀驱动电路进行分析的基础上,提出了一种基于电磁阀自身的自升压方式,一方面把高速电磁阀关闭时本身储存的电能回收到储能电容中,另一方面在两缸工作间隙利用电磁阀线圈作为升压电路电感对储能电容进行能量补充,保证储能电容上的电压达到一个稳定状态。电路在保证实现双电压快速驱动的同时,使驱动结束的能量得到有效回收,同时省去外接专用升压电路所需要的电感部件,减小了电源电路的体积和设计成本,并且电控单元印制线路板的电磁兼容性设计易于保证。应用该方法对某高压共轨部件高速电磁阀进行试验,匹配出驱动参数,并进行稳定性试验验证,结果表明该方法能够满足工程应用需求。     

基于GPS载波相位信号确定运动体姿态的关键技术

应用GPS载波相位信号确定运动体姿态,针对二维两天线系统情况,设计了姿态测量系统的硬件结构及算法流程框图,文章介绍了GPS姿态测量的关键技术：GPS姿态观测方程、整周模糊度的解算、误差的消除。从系统设计角度证明了技术的可行性。     

浅谈工程设计对公路建设投资的影响和相应对策

通过工程设计对公路建设投资影响的分析,阐明了工程设计是影响建设投资的主要因素之一,并通过实例证明了合理选择设计方案和采用技术标准等办法是控制投资的一条有效途径,而合理选择设计方案和技术标准又受到各种因素的影响和限制,对影响合理选择设计方案的原因进行了具体分析,并就此提出了几点相应对策,供同行们参考.     

哈绕城高速公路东北段松花江大桥主桥设计方案研究

该松花江大桥为绕城高速公路东北段跨越松花江的一座特大桥,本文介绍了该桥三个桥型方案,并从结构受力、施工难易程度、耐久性、工程经济等方面进行比选提出推荐方案。     

彩色多普勒超声在动态监测移植肝及其并发症中的应用

目的探讨彩色多普勒超声在动态监测肝移植术后血流动力学变化及并发症诊治中的应用价值。方法回顾我中心107例原位肝移植术后应用彩色多普勒超声资料,汇总后行统计学分析。结果肝移植术后早期门脉流速较正常对照组升高,而肝动脉流速降低,后逐渐恢复正常。107例中发现肝动脉血栓形成2例(1.87%),肝动脉狭窄5例(4.67%),门脉血栓形成3例(2.80%),肿瘤复发7例(6.54%),诊断为急性排斥反应18例次(16.82%),慢性排斥反应10例次(9.34%),胸腔积液105例(98.13%),腹腔积液65例(60.74%),假性动脉瘤1例,胰漏1例,胆道感染4例(3.74%),胆道狭窄4例(3.74%),胆漏5例(4.67%),胆总管结石1例。结论彩色多普勒超声在动态监测肝移植术后血流动力学变化及并发症诊治中具有重要的临床意义。     

Study on T lymphocyte subsets and NK cells in patients with Graves＇ disease combined with type 2 diabetes

Objective To investigate changes in T lymphocyte subsets and NK cells in patients with simple Graves' disease (GD)and Graves' disease combined with type 2 diabetes mellitus (GD/T2DM). Methods Fifteen cases of GD/ T2DM were selected from our hospital from November 2001 to November 2004. Before and after therapy thyroid function, thyroglobulin antibody (TGA), thyroid microsomal antibody (TMA) and blood glucose level were measured, and T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) and NK cells (CD56) were measured by immunofluorescence double labeling monoclonal antibody and flow cytometry, respectively. At the same time, comparison was made with simple GD (15 cases), T2DM (15 cases) and healthy control (20 cases). Results Before therapy, CD4/CD8, CD4 and NK cells in GD/T2DM were less than normal, and there was no significant difference in comparison with simple GD (P<0.05). In T2DM group, only CD4/CD8 and CD4 were less than those of healthy controls (P<0.05). When thyroid function recovered after 1 to 3 months of methimazole treatment in both GD/T2DM and simple GD groups, various indexes recovered, which were more obvious in simple GD. Conclusion Immune hypofunction of GD may be the key to the immune abnormality of GD/T2DM, which is more significant than that of simple GD or T2DM. The recovery of thyroid function and immune abnormality is not consistent, and the recovery of GD is more significant than that of GD/T2DM.     

2型糖尿病患者一级亲属正常糖代谢人群胰岛素抵抗分析

目的探讨2型糖尿病(T2DM)患者糖耐量正常的一级亲属胰岛β细胞功能及胰岛素抵抗情况,并分析胰岛素抵抗的相关因素。方法选取T2DM患者糖耐量正常的一级亲属63例,根据胰岛素抵抗指数分为胰岛素抵抗组及非抵抗组;选取30例健康体检者作为正常对照组。对所选的93例对象进行血压、血糖、胰岛素、血脂的测定,并计算稳态模型胰岛素抵抗指数(HOMA-IR)及胰岛β细胞功能指数(HOMA-β)。结果①糖尿病患者一级亲属组与对照组相比,胰岛素水平、HOMA-IR、HOMA-β明显升高(P<0.05);②胰岛素抵抗组体质指数、舒张压、甘油三酯、餐后血糖、HOMA-β明显高于胰岛素非抵抗组(P<0.05);③相关分析示胰岛素抵抗与体质指数、舒张压、甘油三酯、餐后胰岛素呈正相关(P<0.01,P<0.05),与空腹血糖、餐后血糖、空腹胰岛素、收缩压、胆固醇无显著相关性(P>0.05)。结论T2DM患者一级亲属存在胰岛β细胞代偿性的高分泌,早期已经出现胰岛素敏感性的下降和胰岛素抵抗。胰岛素抵抗与体重增加、舒张压升高及甘油三酯的升高有关。提示对糖尿病患者一级亲属应严格控制体重、血压及血脂,对减少T2DM具有积极意义。