在大学生中开展礼育是构筑和谐社会的重要环节

现代高校德育在市场经济大潮中困惑重重,德育内容与现实脱节,大学生的道德知行分离现象严重,一些不和谐现象发人深思。“礼”是人类文明最基本的特征和最重要的标志之一。“礼”不仅仅是用来交际的手段,更是一种成于内而形于外的文化积淀。今天的在校大学生将是明天国家的中坚,他们的行为举止不仅反应一个国家的文明程度,同时也将对社会产生良好的示范作用。在大学生中大力开展礼育将是构筑和谐社会的重要环节。     

船用D36钢焊接工艺

根据现代船舶发展,船用高强度钢也逐步用在船体结构的制造中,文章以D36钢为例,结合高强度钢的特点从焊接材料选择、焊前准备、焊接过程、焊后检验等方面详细介绍焊接工艺过程及焊接质量控制中应该注意的问题,总结出实际生产中高强度钢的焊接工艺。     

以市场需求为导向的高职物流专业教学改革思考

文章分析了我国物流企业人才需求现状和高职物流专业教学现状,从课程体系、实践教学和师资队伍三个方面提出了以市场需求为导向的高职物流专业教学改革的思路。     

纯电动客车特殊工况下传动系NVH的性能试验研究

对某10 m纯电动客车传动系进行加速和制动工况下的NVH性能试验研究,为纯电动客车的NVH性能改善提供参考.     

钢壳沉管端钢壳三维姿态验收测量技术

在钢壳沉管隧道施工中,钢壳管节浇筑前后的验收主要是对端钢壳进行三维姿态测量,主要包括端钢壳面板(端面板)平整度、端钢壳横向垂直度(水平偏角)和竖向倾斜度(竖向偏角),目的是保证沉管精确地沉放安装。根据深中通道沉管隧道端钢壳施工验评标准,要求端钢壳总体测量精度达到mm级,难度较大。为满足测量精度,采用了一种钢壳沉管三维姿态测量技术,主要是利用高精度全站仪+全圆法观测软件+MATLAB数学软件对钢壳沉管端钢壳三维姿态进行测量并处理分析各项数据指标,评定端钢壳在钢壳管节浇筑前后的精度,同时能确保工序之间合理衔接。     

落石撞击桥墩计算模型研究现状与展望

为了对桥墩进行科学的落石撞击验算及防落石撞击设计,分类整理了国内外相关研究成果,从落石撞击力的静力计算方法、简化动力计算方法、桥墩损伤特征及影响因素等方面进行了分析论述,为桥墩落石撞击验算及防落石撞击设计提供参考。对落石撞击力及结构撞击响应计算提出了建议和展望。     

NOVEL SPLICING MUTATION OF COL1A1 GENE CAUSING OSTEOGENESIS IMPERFECTA TYPE I IN CHINESE PEDIGREE

Objective To detect the peculiar mutation in a Chinese family with osteogenesis imperfecta,COL1A1 and COL1A2 being analysed. Methods A genome screen was undertaken covering COL1A1 at 17q21-22 and COL1A2 at 7q22.1. The Linkage ( Version 5.1 ) was used for 2-point analysis. DNA sequencing was used to screen and identify the mutation. Results A linkage to the markers on chromosome 17q21-22 was observed. Sequence analysis of COL1A1 revealed a splicing mutation ( IVS8-2A ＞ G) that converted the 3' end of intron 8 from AG to GG. Conclusion This mutation ( IVS 8-2A ＞ G) is novel, and has not yet been registered in the Human Type Ⅰ and Type Ⅲ Collagen Mutations Database.     

DIFFERENTIAL EXPRESSION OF GENES IN OMENTAL FAT OF NORMAL WEIGHT AND OBESE SUBJECTS AND OBESE DIABETIC PATIENTS USING cDNA MICROARRAY

Objective To identify genes differentially expressed in omental fat of normal weight subjects,obese subjects and obese diabetic patients. Methods Using a high-density cDNA microarray, gene expression profile of omental fat from normal weigh subjects, obese subjects and obese diabetic patients were compared.Results Totally, 119 and 257 genes were up-regulated in obese subjects and obese diabetic patients respectively,while 46 and 58 genes were down-regulated. A total of 77 genes, including PDK4, which switched from carbohydrate to fatty acids as the primary source of fuel, were up-regulated in both obese and obese diabetic patients, while 8 genes, including key enzymes in lipid synthesis, such as HMG-CoA synthase, fatty acid synthase and stearoyl-CoA desaturase, were down-regulated in both groups. Tyrosine-3-monooxygenase/tryptophan 5-monooxygenase activation protein θ ( YWHAZ) , a negative regulator for insulin signal transduction, was up-regulated only in obese diabetic patient, but not in normal-glycemic obese subjects. Conclusion The study demonstrated that decrease of lipogenesis along with increase of fatty acids oxidation of adipose tissue could be a common cause of insulin resistance in obesity and type 2 diabetes, while block of insulin signal transduction may trigger the transition from obesity to diabetes. Further exploration of these genes will be useful in the understanding of the pathogenesis of obesity and diabetes.     

INTRAOPERATIVE LOCALIZATION OF CORTICAL MOTOR EVOKED POTENTIALS IN CENTRAL SULCUS LESIONS

Objective To study direct cortical electrical stimulation technique for the recording of motor evoked potentials under general anesthesia in central sulcus lesions. Methods The largest N20-P25 response was recorded from postcentral gyrus by intraoperative monitoring of cortical motor evoked potentials in 10 patients with intracranial lesions near or in the central area. The muscles of upper extremity in all patients were activated by delivering stimulus to cortical areas continuously. Moving the cortical electrodes forward, the largest P20-N25 response, SEP phase reversal,was obtained as a motor center stimulus. In this site of cortex, a short train stimulation elicited reproducible muscle action potentials that could be observed from the oscilloscope without averaging.Results MEPs can be recorded, pre- and post-operatively, without motor deficits of upper limbs in all patients.Conclusion This technique seems to be preferable for intraoperative localization of motor evoked potentials in central sulcus lesions under total intravenous anesthesia.     

有效压缩比及再循环废气对直喷汽油机燃油消耗的影响

针对一款2.0 L自然吸气缸内直喷汽油机,通过调整配气相位,试验研究了有效压缩比和外部EGR对发动机燃油消耗的影响.研究结果表明:有效压缩比对燃油消耗率影响显著,降低有效压缩比,能够抑制爆震,改善燃油消耗.试验所选工况范围内,低有效压缩比相对高有效压缩比方案燃油消耗率降低2.7％,热效率提升1个百分点,但低有效压缩比情...