舒林酸对结肠癌细胞SW480FasL蛋白表达及诱导淋巴细胞凋亡的影响

目的在体外通过细胞培养,探讨舒林酸对结、直肠癌发生、发展的化学预防机制。方法应用Western blot法检测舒林酸作用前后SW480细胞FasL蛋白表达的变化;应用流式细胞术检测舒林酸作用前后SW480细胞诱导淋巴细胞凋亡率的变化。结果舒林酸处理后较处理前SW480细胞FasL蛋白表达明显降低,而且FasL蛋白表达随舒林酸作用浓度增加显著降低;随舒林酸作用浓度升高,SW480细胞诱导淋巴细胞凋亡率明显降低,不同浓度组比较均有显著性差异(P<0.01)。结论舒林酸降低结肠癌SW480细胞FasL蛋白表达,使SW480细胞诱导Jurkat细胞凋亡率降低,可能是其对结、直肠癌发生、发展的化学预防机制。     

制动条件下连挂救援动车组车钩垂向偏转行为

为了研究连挂救援动车组在制动条件下产生的冲击,建立了不同编组形式下的动车组动力学模型。考虑实际的车钩运动关系和缓冲器迟滞特性,建立了钩缓装置的动力学模型。制定了连挂救援动车组的运行安全阈值,分析了紧急制动时动车和钩缓系统的动力学响应,研究了直线工况下车钩的动态偏转行为与动车编组形式、制动减速度和车钩自由转角等参数对动车组运行安全性的影响。计算结果表明:A类动车组连挂救援B类动车组,直线上制动时连挂断面的压钩力和车钩点头角分别达到799.4kN和11.5°,钩尾框托梁垂向力和车端垂向相对位移分别达到136.2kN和126.2mm,明显超过允许限值,即80kN和95mm,车钩力垂向分量会造成车体点头和轮重减载现象,从而导致局部结构破坏和车间运动干涉。当制动档位降到7级或车钩自由点头角低至4°时,钩尾框前箱托梁垂向力低于限值,而车端垂向相对位移超过限值;当制动档位降到6级或车钩自由点头角低至2°时,可保证车端垂向相对位移低于允许值。     

Load distribution on the hull-leg connection components of a jack-up

The jacking pinions and rack chocks of the fixation system of a jack-up sustain tremendous load in the elevated condition, especially when there exists a remarkable non-uniformity of the load distribution. Failures of these structural components may lead to disastrous consequence of the jack-up. Despite the importance of these components, it is difficult to give an accurate prediction of the load distribution on these components in engineering application due to the complex nonlinear interaction mechanism, which is influenced by the relative stiffness of the components, leg-guide clearance and backlash. Previous studies mainly focus on the global performance of the jack-up and pay little attention to the load distribution on the pinions and chocks. The strength of the jacking system is often guaranteed by the manufacturer for an estimate load level, which brings in uncertainty to the safety of the jack-up. The characteristics of the hull-leg interaction are discussed in this paper, and a simplified method using gap elements is proposed. The nonlinear structural analyses are carried out for a specific jack-up using the proposed method and the three-dimensional finite element method(FEM) with contact algorithm. The proposed method is proved accurate and effective for the engineering application. The characteristics of the load distribution of the specific jack-up are discussed, and the conclusions are presented.     

控制G2021油罐地基变形的方法

针对G2021油罐地基的特点,通过复合地基的稳定性与变形分析,采用控制振冲碎石桩的密度,掌握充水预压的水量和时间进行固结处理地基,使差异变形满足了要求。     

On constructing certificateless proxy signature from certificateless signature

In proxy signature schemes, an original signer A delegates its signing capability to a proxy signer B, in such a way that B can sign message on behalf of A.The recipient of the final message verifies at the same time that B computes the signature and that A has delegated its signing capability to B.Recently many identity-based(ID-based) proxy signature schemes have been proposed, however, the problem of key escrow is inherent in this setting.Certificateless cryptography can overcome the key escrow problem.In this paper, we present a general security model for certificateless proxy signature scheme.Then, we give a method to construct a secure certificateless proxy scheme from a secure certificateless signature scheme, and prove that the security of the construction can be reduced to the security of the original certificateless signature scheme.     

超声波-铁氧体法处理含铬废水的实验研究

本实验使用超声波-铁氧体法对含铬废水进行处理,通过考察硫酸亚铁用量、pH值、H2O2用量、超声波的辐射时间和辐射功率对含铬废水铬去除率以及铁氧体磁性的影响,设计超声波-铁氧体法处理含铬废水的最佳操作条件.结果表明,随着硫酸亚铁用量的增加,Cr6 的去除率增大,最佳pH为9.0,当Fe2 :Cr6 =6∶1(mol∶mol)、超声波辐射时间和辐射功率分别是30 min和50 W/cm2时,去除率高达到99.9%以上,H2O2用量为1.0~2.0 mL,铁氧体的磁性最强.     

制冷剂/压缩机油与PA6的相容性研究

采用红外光谱分析和热重分析研究了不同规格PA6(聚酰胺6或尼龙6)的区别,不同规格PA6的红外谱图有细微区别,PA6在350℃之前的热失重量不同,可见其增塑剂等小分子的含量不同,这不但影响PA6的耐热老化性能,还会明显影响PA6的挤出工艺和使用性能.通过PA6在制冷剂、压缩机油、制冷剂/压缩机油等介质中的热老化测试和测...